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Studii Catalog

Vitamine si Minerale

 Alive!® Calcium + D3 Gummies

(1)     BirgitHolst, GaryWilliamson, " Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants",
Current Opinion in Biotechnology, Volume 19, Issue 2, April 2008, Pages 73-82

 

Alive!™ Men’s 50+ Ultra

(1)     BirgitHolst, GaryWilliamson, " Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants",
Current Opinion in Biotechnology, Volume 19, Issue 2, April 2008, Pages 73-82.

(2)    Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu et. Al., " AN UP-TO-DATE REVIEW OF RUTIN AND ITS BIOLOGICAL
AND PHARMACOLOGICAL ACTIVITIES", EXCLI Journal 2015;14:59-63 – ISSN 1611-2156.

(3)    Dinesh Kumar; Vikrant Arya; Zulfiqar Ali Bhat; Nisar Ahmad Khan; Deo Nandan Prasad; The genus Crataegus: chemical and pharmacological perspectives; Rev. bras. farmacogn. vol.22 no.5 Curitiba Sept./Oct. 2012 Epub Aug 16, 2012.

(4)   Hai-Rong Yu, Yu-Lian Jiang, Dan-Dan Dong, Guo-Hong Wang; Cardioprotective effects of the total flavonoids of Polygonum cuspidatum Sieb. et Zucc. Root extract on experimental myocardial infarction in mice; Tropical Journal of Pharmaceutical Research; Vol 18, No 2 (2019).Abhinav Sharma , Gregg C. Fonarow , Javed Butler , Justin A. Ezekowitz , and G. Michael Felker; Coenzyme Q10 and Heart Failure, A State-of-the-Art Review; Vol. 9, No. 4; Originally published24 Mar 2016.

 

Alive!™ Men’s Ultra

(1)     BirgitHolst, GaryWilliamson, " Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants",
Current Opinion in Biotechnology, Volume 19, Issue 2, April 2008, Pages 73-82.

(2)    Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu et. Al., " AN UP-TO-DATE REVIEW OF RUTIN AND ITS BIOLOGICAL
AND PHARMACOLOGICAL ACTIVITIES", EXCLI Journal 2015;14:59-63 – ISSN 1611-2156.

(3)    Dinesh Kumar; Vikrant Arya; Zulfiqar Ali Bhat; Nisar Ahmad Khan; Deo Nandan Prasad; The genus Crataegus: chemical and pharmacological perspectives; Rev. bras. farmacogn. vol.22 no.5 Curitiba Sept./Oct. 2012 Epub Aug 16, 2012.

(4)   Hai-Rong Yu, Yu-Lian Jiang, Dan-Dan Dong, Guo-Hong Wang; Cardioprotective effects of the total flavonoids of Polygonum cuspidatum Sieb. et Zucc. Root extract on experimental myocardial infarction in mice; Tropical Journal of Pharmaceutical Research; Vol 18, No 2 (2019).

(5)    Abhinav Sharma , Gregg C. Fonarow , Javed Butler , Justin A. Ezekowitz , and G. Michael Felker; Coenzyme Q10 and Heart Failure, A State-of-the-Art Review; Vol. 9, No. 4; Originally published24 Mar 2016.

 

Alive!™ Women’s 50+ Ultra

(1)  BirgitHolst, GaryWilliamson, " Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants",
Current Opinion in Biotechnology, Volume 19, Issue 2, April 2008, Pages 73-82.

(2) Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu et. Al., " AN UP-TO-DATE REVIEW OF RUTIN AND ITS BIOLOGICAL
AND PHARMACOLOGICAL ACTIVITIES", EXCLI Journal 2015;14:59-63 – ISSN 1611-2156.

 

Alive!™ Women’s Ultra

(1)  BirgitHolst, GaryWilliamson, “ Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants”,
Current Opinion in Biotechnology, Volume 19, Issue 2, April 2008, Pages 73-82.

(2) Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu et. Al., “ AN UP-TO-DATE REVIEW OF RUTIN AND ITS BIOLOGICAL
AND PHARMACOLOGICAL ACTIVITIES”, EXCLI Journal 2015;14:59-63 – ISSN 1611-2156.

 

Alive!™ (fără fier adăugat)

 

(1)BirgitHolst, GaryWilliamson, “ Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants”,
Current Opinion in Biotechnology, Volume 19, Issue 2, April 2008, Pages 73-82.

(2) Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu et. Al., “ AN UP-TO-DATE REVIEW OF RUTIN AND ITS BIOLOGICAL
AND PHARMACOLOGICAL ACTIVITIES”, EXCLI Journal 2015;14:59-63 – ISSN 1611-2156.

 

 

Calcium Citrate Complex

(6) Abhijit Trailokya, Ambrish Srivastava, Milind Bhole, Nitin Zalte, ˝ Calcium and Calcium Salts˝, Journal of The Association of Physicians of India ■ Vol. 65 ■ February 2017

 

Chromium GTF 200 mcg

(7) Darryn Willoughby, Susan Hewlings and Douglas Kalman; Body Composition Changes in Weight Loss: Strategies and Supplementation for Maintaining Lean Body Mass, a Brief Review; Nutrients 2018, 10(12), 1876.

 

Daily D3+K2

(61) https://www.hindawi.com/journals/isrn/2013/898125/
(62) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688475/
(63) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901845/#:~:text=Vitamin%20D%20and%20its%20receptor,in%20tests%20of%20muscle%20performance.
(64) https://pubmed.ncbi.nlm.nih.gov/23744412/
(65) https://www.tandfonline.com/doi/full/10.1080/1028415X.2017.1317395?scroll=top&needAccess=true
(66) Zoch ML, Clemens TL, Riddle RC. New insights into the biology of osteocalcin. Bone. 2016 Jan;82:42-9
(67) van Ballegooijen AJ, Pilz S, Tomaschitz A, et al. The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. Int J Endocrinol. 2017;2017:7454376.
(68) https://pubmed.ncbi.nlm.nih.gov/30791399/
(69) https://cardiab.biomedcentral.com/articles/10.1186/s12933-015-0237-9
(70) https://www.hindawi.com/journals/bmri/2012/634195/
(71) https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2014.3579
(72) https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2015.4096
(73) https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2009.1227
(74) https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2010.1468
(75) https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2012.2714
(76) https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2009.1228
(77) https://sci-hub.se/https://doi.org/10.1016/j.diabres.2017.11.020
(78) https://www.mikronaehrstoffcoach.com/en/micronutrients/micronutrient.vitamin-d.html
(79) https://www.naturalproductsinsider.com/immune-health/potential-vitamins-d-and-k2-immune-system

 

Daily-D3 2000 UI

(37) Ruth E. Grossmann and Vin Tangpricha, “Evaluation of vehicle substances on vitamin D biovailability: A systematic review”, Mol Nutr Food Res. Author manuscript; available in PMC 2011 Feb 3.
(48) https://www.hindawi.com/journals/bmri/2012/634195/
(49) https://pubmed.ncbi.nlm.nih.gov/23744412/
(50) https://www.tandfonline.com/doi/full/10.1080/1028415X.2017.1317395?scroll=top&needAccess=true
(51) https://www.researchgate.net/publication/256460329_Practical_guidelines_for_the_supplementation_of_vitamin_D_and_the_treatment_of_defcits_in_Central_Europe_-_Recommended_vitamin_D_intakes_in_the_general_population_and_groups_at_risk_of_vitamin_D_defic/link/552b82080cf29b22c9c1b6c4/download
(52) https://pubmed.ncbi.nlm.nih.gov/20642395/
(53) https://pubmed.ncbi.nlm.nih.gov/27860257/
(54) http://www.ms.ro/wp-content/uploads/2019/07/Anexa2-Ghid-pentru-evaluarea-statusului-vitaminei-D-la-adulti-1-1.pdf
(55) https://www.frontiersin.org/articles/10.3389/fphys.2019.00194/full
(56) https://www.hindawi.com/journals/isrn/2013/898125/
(57) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688475/
(58) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901845/#:~:text=Vitamin%20D%20and%20its%20receptor,in%20tests%20of%20muscle%20performance.
(59) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465887/
(60) https://cardiab.biomedcentral.com/articles/10.1186/s12933-015-0237-9
(81) Victoria F. Logan, Andrew R. Gray et. AL., " Long-term vitamin D3 supplementation is more effective than vitamin D2 in maintaining serum 25-hydroxyvitamin D status over the winter months", Published online by Cambridge University Press: 11 July 2012

 

Folic Acid

(8) Nancy S. Green, ˝ Folic Acid Supplementation and Prevention of Birth Defects1,2˝, Trans-HHS Workshop:
Diet, DNA Methylation Processes and Health, © 2002 American Society for Nutritional Sciences.

 

Iron Complex +

(9) Marzieh Zargaran, Ebrahim Saadat, Rassoul Dinarvand, Mohammad Sharifzadeh, Farid Dorkoosh; Preparation and Bioavailability Analysis of Ferrous Bis Alanine Chelate as a New Micronutrient for Treatment of Iron Deficiency Anemia; Advanced Pharmaceutical Bulletin; 2016, 6(3), 407-413.
(10) D A Hughes, S E Stuart-Smith, and B J Bain; How should stainable iron in bone marrow films be assessed?
D A Hughes, S E Stuart-Smith, and B J Bain; Journal of Clinical Pathology; 2004 Oct; 57(10): 1038–1040.
(11) Roberto Miniero, Valentina Talarico, Maria Concetta Galati, Laura Giancotti, Paola Saracco and Giuseppe Raiola; Iron Deficiency and Iron Deficiency Anemia in Children; Submitted: March 8th 2018Reviewed: June 27th 2018Published: November 5th 2018.
(12) Madhumita Jagannathan-Bogdan and Leonard I. Zon, ˝Hematopoiesis˝, Development. 2013 Jun 15; 140(12): 2463–2467.

 

Methylcobalamin (Vitamina B12) 5000 mcg

(13) https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/methylcobalamin
(14) Herbert V. Vitamin B12 in Present Knowledge in Nutrition.
17th ed. Washington, DC: International Life Sciences Institute Press, 1996.
(15) Gianluca Rizzo, Antonio Simone Laganà et. Al; Vitamin B12 among Vegetarians: Status, Assessment and Supplementation, Nutrients ; 2016, 8(12), 767; doi:10.3390/nu8120767.

 

OptiZinc® 30 mg

(16) Chien XX, Zafra-Stone S, Bagchi M, Bagchi D. Biodisponibilitatea și proprietățile antioxidante și imunostimulatoare ale metionatului de zinc (combinație zinc-metionină). BioFactors (2006), 27(1-4): 231–244.
(17) Marcelina Parra, Seth Stahl, and Hanjo Hellmann, ˝ Vitamin B6 and Its Role in Cell Metabolism and Physiology˝, Cells. 2018 Jul; 7(7): 84.

 

Potassium 99 mg

(18) Michael S. Stone, Lisa Martyn, Connie M. Weaver, ”Potassium Intake, Bioavailability, Hypertension, and Glucose Control’’, Nutrients. 2016 Jul; 8(7): 444.

 

Selenium 200mcg

(19) Nora M. Griffiths , R. D. H. Stewart , Marion F. Robinson, "The metabolism of [75Se]selenomethionine in four women",
Published online: 25 March 2008.

 

Super Bio Vitamin C

(20) Gene Bruno, ˝Vitamin C & Bioflavonoids", ©2002 Huntington College of Health Sciences

 

Vitamin C 1000mg (adulți) 100 cps

(20) Gene Bruno, ˝Vitamin C & Bioflavonoids", ©2002 Huntington College of Health Sciences
(21) Carr, A. C., & Maggini, S. (2017). Vitamin C and Immune Function. Nutrients, 9(11), 1211. https://doi.org/10.3390/nu9111211
(22) https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
(23) Pehlivan F. E., Vitamin C: An Antioxidant Agent, 2017
(24) Aghajanian, P., Hall, S., Wongworawat, M. D., & Mohan, S. (2015). The Roles and Mechanisms of Actions of Vitamin C in Bone: New Developments. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(11), 1945–1955. https://doi.org/10.1002/jbmr.2709
(25) Devaki S. J., & Raveendran R. L., Vitamin C: Sources, Functions, Sensing and Analysis, 2017, DOI: 10.5772/intechopen.70162
(26) https://www.oralhealthgroup.com/features/vitamin-c-update-implications-periodontal-health-healing/#:~:text=VITAMIN%20C%20IS%20IMPORTANT%20FOR,for%20the%20synthesis%20of%20collagen
(27) May, J. M., & Harrison, F. E. (2013). Role of vitamin C in the function of the vascular endothelium. Antioxidants & redox signaling, 19(17), 2068–2083. https://doi.org/10.1089/ars.2013.5205
(28) Figueroa-Méndez R,, Rivas-Arancibia S., Vitamin C in Health and Disease: Its Role in the Metabolism of Cells and Redox State in the Brain, Frontiers in Physiology, 2015, DOI=10.3389/fphys.2015.00397
(29) Hallberg L, Brune M, Rossander L. The role of vitamin C in iron absorption. Int J Vitam Nutr Res Suppl. 1989;30:103-8. PMID: 2507689.

 

Vitamin C 1000mg (adulți) 30 cps

(20) Gene Bruno, ˝Vitamin C & Bioflavonoids", ©2002 Huntington College of Health Sciences

 

Vitamin C Express

(30). Gitte S. Jensen, Kimberlee A. Redman et. All, “ Antioxidant Bioavailability and Rapid Immune-Modulating Effects After Consumption of a Single Acute Dose of a High-Metabolite Yeast Immunogen: Results of a Placebo-Controlled Double-Blinded Crossover Pilot Study”, JOURNAL OF MEDICINAL FOOD, 14 (X) 2011, 1–9.
(31). https://epicorimmune.com/research/
(32). https://epicorimmune.com/what-is-epicor/#what-is-ecpicor
(33). Sam Possemiers, Iris Pinheiro, An Verhelst, et. Al., “ A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach”, J Agric Food Chem 2013 Oct 2;61(39):9380-92. doi: 10.1021/jf402137r. Epub 2013 Sep 19.
(34). Selma P Wiertsema, Jeroen van Bergenhenegouwen, Johan Garssen, Leon M J Knippels, “ The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies”, Nutrients 2021 Mar 9;13(3):886. doi: 10.3390/nu13030886.

 

Vitamin C Liposomal 500 mg

(35) Pokorski M, Marczak M. et. al., "Ascorbyl Palmitate as a Carrier of Ascorbate into Neural Tissues", Journal of Biomedical Science.
(36) Janelle L. Davis, Hunter L. Paris et. al., ˝ Liposomal-encapsulated Ascorbic Acid: Influence on Vitamin C Bioavailability and Capacity to Protect Against Ischemia–Reperfusion Injury˝, Nutrition and Metabolic Insights 2016:9 25–30 doi:10.4137/NMI.S39764.

 

Vitamin D3 2000 UI 120cps/30 cps

(37) Ruth E. Grossmann and Vin Tangpricha, “Evaluation of vehicle substances
on vitamin D biovailability: A systematic review”, Mol Nutr Food Res. Author
manuscript; available in PMC 2011 Feb 3.

 

Vitamin D3 5000 UI

(37) Ruth E. Grossmann and Vin Tangpricha, “Evaluation of vehicle substances
on vitamin D biovailability: A systematic review”, Mol Nutr Food Res. Author
manuscript; available in PMC 2011 Feb 3.

(38) Seria Protocoale în îngrijirea anemiei și rahitismului la
copil, Ministerul Sănătății, Institutul pentru Ocrotirea Mamei și Copilului, ‘’Prof. Dr. Alfred Rusescu’’.
(39) Studiu: FACTORI REGLATORI AI METABOLISMULUI FOSFOCALCIC ÎN CONDIȚII FIZIOLOGICE ȘI DE BOALĂ. Conducător Științific: Prof. Univ. Dr. Dumitru D. BRĂNISTEANU, Doctorand :Alina-Andreea GÂTU); studiu efectuat pe 93 de pacienți (82 femei și 11 bărbati, cu vârste cuprinse între 23-85 ani), internați în perioada februarie 2014-februarie 2015 în Clinica de Endocrinologie a Spitalului Clinic Județean de Urgente „Sf. Spiridon” Iași, 2017.

 

Vitamin D3 Gummy

(38) Seria Protocoale în îngrijirea anemiei și rahitismului la
copil, Ministerul Sănătății, Institutul pentru Ocrotirea Mamei și Copilului, ‘’Prof. Dr. Alfred Rusescu’’.
(40) https://pubmed.ncbi.nlm.nih.gov/21872800/
(41) Michelle E. Fullard, John E. Duda, “ A Review of the Relationship Between Vitamin D and Parkinson Disease Symptoms”, Front. Neurol., 27 May 2020, Sec. Movement Disorders, Volume 11 - 2020 | https://doi.org/10.3389/fneur.2020.00454
(42) https://rjmp.com.ro/articles/2019.3/RJMP_2019_3_Art-04.pdf
(43) https://www.mdpi.com/2072-6643/10/10/1395
(44) https://www.hsph.harvard.edu/nutritionsource/vitamin-d/
(45) https://www.mdpi.com/1422-0067/23/17/9784

 

Vitamin B-Complex 100

(80) Nootropic Vitamins and Minerals – Essential Nutrients for Optimal Brain Health and Cognitive Function; July 24, 2018.

 

Magnesium 500 mg

 

(101) Etienne Pouteau, Marmar Kabir-Ahmadi et. Al.," Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial", Published: December 18, 2018.
(102) Mary P. Guerrera, Stella Lucia Volpe, Jun James Mao, ˝ Therapeutic Uses of Magnesium˝, American Family Physician , July 15, 2009 V Volume 80, Number 2.

 

Vitamin K-2 100mcg

(59) Leon J. Schurgers, Kirsten J. F. Teunissen et. al., ‘’Vitamin K–containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7’’, The American Society of Hematology, 2007.
(103) Katarzyna Maresz, ‘’ Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health’’, Integr Med (Encinitas). 2015 Feb; 14(1): 34–39.

 

Methyl B-12 (Vitamina B12) 500 mcg

(82) https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
(83) https://www.health.com/vitamin-b12-7252832
(84) https://openoregon.pressbooks.pub/nutritionscience/chapter/9e-energy-metabolism vitamins-minerals/
(85) https://draxe.com/nutrition/vitamin-b12-benefits/
(86)bhttps://link.springer.com/article/10.1186/s12929-016-0241-8
(87) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085763/
(88) https://www.revistagalenus.ro/practica-medicala/homocisteina-si-mutatiile-mthfr-2
(89) https://www.medichub.ro/reviste/psihiatru-ro/implicatiile-polimorfismelor-genei-mthfr-in-etiologia-schizofreniei-id-1107-cmsid-66
(90) https://quatrefolic.com
(91) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616856/
(92) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380836/
(93) https://journals.sagepub.com/doi/pdf/10.1177/0310057X1604400410
(94) https://pubmed.ncbi.nlm.nih.gov/15189115/
(95) https://www.sciencedirect.com/science/article/abs/pii/S1359511323000363
(96) https://www.nhlbi.nih.gov/health/anemia/vitamin-b12-deficiency-anemia
(97) https://pubmed.ncbi.nlm.nih.gov/8914118/
(98) https://www.frontiersin.org/10.3389/conf.fphar.2010.60.00140/event_abstract
(99) https://www.sciencedirect.com/topics/medicine-and-dentistry/mecobalamin
(100) https://pubmed.ncbi.nlm.nih.gov/34791425/

 

Nutritie si Metabolism

 

Glucose Optimizer®

(1) Rajya Lakshmi, Puttagunta Srinivasa Babu; A REVIEW ON LAGERSTROEMIA SPECIOSA; Article in International Journal of Pharmaceutical Sciences and Research 8(11) · November 2017.

(2) Javed Ahamad, Saima Amin; Momordica charantia Linn. (Cucurbitaceae): Review on Phytochemistry and Pharmacology; Article (PDF Available) in Research Journal of Phytochemistry 11(2):53-65 · March 2017.
(3) Jimmy T. Efird, Yuk Ming Choi, Stephen W. Davies, Sanjay Mehra, Ethan J. Anderson, and Lalage A. Katunga; Potential for Improved Glycemic Control with Dietary Momordica charantia in Patients with Insulin Resistance and Pre-Diabetes; Int J Environ Res Public Health. 2014 Feb; 11(2): 2328–2345.
(4) Darryn Willoughby, Susan Hewlings and Douglas Kalman; Body Composition Changes in Weight Loss: Strategies and Supplementation for Maintaining Lean Body Mass, a Brief Review; Nutrients 2018, 10(12), 1876.
(5) Saeid Golbidi, Mohammad Badran, and Ismail Laher, Diabetes and Alpha Lipoic Acid; Front Pharmacol. 2011; 2: 69.
(6) Adi Y. Berman, Rachel A. Motechin, Maia Y. Wiesenfeld & Marina K. Holz; The therapeutic potential of resveratrol: a review of clinical trials; Precision Oncologyvolume 1, Article number: 35 (2017).

 

Sure Stevia

(7) S. K. GOYAL; Samsher; R K Goyal; Stevia (Stevia rebaudiana) a bio-sweetener: A review; International Journal of Food Sciences and Nutrition 61(1):1-10· December 2009.

 

Berberine

(8) https://restorativemedicine.org/library/monographs/berberine/
(9) Xinmei Xu, Huan Yi et. AL., “ Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence”, Biomedicine & Pharmacotherapy, Volume 133, January 2021, 110984
(10) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567055/
(11) https://www.sciencedirect.com/science/article/pii/S1568163711000778
(12) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307759/
(13) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307759/
(14) https://www.sciencedirect.com/science/article/pii/S0753332220303292
(15) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028834/

 

L-Carnitine 500 mg

(15) https://examine.com/supplements/l-carnitine/research/
(16) https://lpi.oregonstate.edu/mic/dietary-factors/L-carnitine
(17) Kei Fukami, Sho-ichi Yamagishi et. Al., ˝Potential Inhibitory Effects of l-Carnitine Supplementation on Tissue Advanced Glycation End Products in Patients with Hemodialysis˝, Rejuvenation Res. 2013 Dec 1; 16(6): 460–466.(18) https://www.verywellmind.com/what-is-acetylcholine-2794810

 

L-Methionine 500 mg

(1)https://www.sciencedirect.com/topics/neuroscience/essential-amino-acids
(2) Roos DH, Puntel RL, Farina M, et al. Modulation of methylmercury uptake by methionine: prevention of mitochondrial dysfunction in rat liver slices by a mimicry mechanism. Toxicol Appl Pharmacol. 2011;252(1):28–35.
(3) http://vorga.org/6-3-280.full.pdf
(4) https://www.ndhealthfacts.org/wiki/Lipotropic_factors
(5) Isabelle Papet, Didier Rémond, Dominique Dardevet, Laurent Mosoni, Sergio Polakof, Marie-Agnès Peyron, Isabelle Savary-Auzeloux, Chapter 21 - Sulfur Amino Acids and Skeletal Muscle, Nutrition and Skeletal Muscle, 2019, Pages 335-363.
(6) Yamagishi Y, Igarashi M, Suzuki A, Suguro S, Hirano SI, Nagaoka I. Evaluation of the effect of methionine and glucosamine on adjuvant arthritis in rats. Exp Ther Med. 2012;4(4):640–644. doi:10.3892/etm.2012.668
(7) Kimio Sugiyama, Yasuo Kushima and Keiichiro Muramatsu, Effects of Methionine, Cystine and Taurine on Plasma Cholesterol Level in Rats Fed a High Cholesterol Diet, Agric. Biol. Chem., 48 (ll), 2897-2899, 1984
(8) Roswitha Siener, Florian Struwe, Albrecht Hesse, Effect of L-Methionine on the Risk of Phosphate Stone Formation, Urology, Volume 98, December 2016, Pages 39-43
(9) THOMAS WILLKE, Methionine Production – a Critical Review.
(10) https://healthfully.com/481316-lack-of-methionine-lysine-in-vegetarian-diets.html

 

NADH 10 mg

(11) https://www.winchesterhospital.org/health-library/article?id=21810
(12) André Rex, Mike‐Percy Hentschke, Heidrun Fink, " Bioavailability of Reduced Nicotinamide‐adenin‐dinucleotide (NADH) in the Central Nervous System of the Anaesthetized Rat Measured by Laser‐Induced Fluorescence Spectroscopy", CPharmacology & Toxicology2002,90, 220–225
(13) WEIHAI YING, " NAD/NADH and NADP/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences", ANTIOXIDANTS & REDOX SIGNALING Volume 10, Number 2, 2008
(14) https://www.webmd.com/vitamins/ai/ingredientmono-1016/nadh

 

Managementul Greutatii

 

Apple Cider Vinegar 500 mg

(1)                   Solaleh SadatKhezri, Atoosa Saidpour, Nima Hosseinzadeh, Zohreh Amiri, Beneficial effects of Apple Cider Vinegar on weight management, Visceral Adiposity Index and lipid profile in overweight or obese subjects receiving restricted calorie diet: A randomized clinical trial, Journal of Functional Foods, Volume 43, April 2018, Pages 95-102.

(2)                  Östman, E., Granfeldt, Y., Persson, L., & Björck, I. (2005). Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. European Journal of Clinical Nutrition, 59(9), 983–988.

(3)                  Boon Kee Beh, Nurul Elyani Mohamad, Swee Keong Yeap, Huynh Ky, Sook Yee Boo, Joelle Yi Heng Chua, Sheau Wei Tan, Wan Yong Ho, Shaiful Adzni Sharifuddin, Kamariah Long, Noorjahan Banu Alitheen, Anti-obesity and anti-infammatory efects of synthetic acetic acid vinegar and Nipa vinegar on highfat-diet-induced obese mice, Scientific Reports, volume 7, Article number: 6664 (2017).

(4)                  Petsiou, E. I., Mitrou, P. I., Raptis, S. A., & Dimitriadis, G. D. (2014). Effect and mechanisms of action of vinegar on glucose metabolism, lipid profile, and body weight. Nutrition Reviews, 72(10), 651–661. doi:10.1111/nure.12125.

 

Cayenne (Ardei-iute) 450 mg

(5)                  Zheng, Jia et al. “Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications.” Bioscience reports vol. 37,3 BSR20170286. 11 May. 2017.

(6)                  Maji, Amal K. and Pratim Banerji. "Phytochemistry and gastrointestinal benefits of the medicinal spice, Capsicum annuum L. (Chilli): a review" Journal of Complementary and Integrative Medicine, 13.2 (2016): 97-122. Retrieved 2 Jul. 2019.

 

Fucoxanthin

(7)                  Ling Huang,Kewei Wen,Xuan Gao, Yonghong Liu, Hypolipidemic effect of fucoidan fromLaminaria japonica in hyperlipidemic rats, Volume 48, 2010 - Issue 4.

(8)                  Jang, Woong Sun, and Se Young Choung. “Antiobesity Effects of the Ethanol Extract of Laminaria japonica Areshoung in High-Fat-Diet-Induced Obese Rat.” Evidence-based complementary and alternative medicine : eCAM vol. 2013 (2013): 492807.

(9)                  Yusrizam Sharifuddin, Yao-Xian Chin, Phaik-Eem Lim, Siew-Moi Phang, Potential Bioactive Compounds from Seaweed for Diabetes Management, Mar. Drugs 2015, 13(8), 5447-5491.

(10)                Storm N. S. Reid, Je-kwang Ryu, Yunsook Kim, and Byeong Hwan Jeon, “The Effects of Fermented Laminaria japonica on Short-Term Working Memory and Physical Fitness in the Elderly,” Evidence-Based Complementary and Alternative Medicine, vol. 2018, Article ID 8109621, 12 pages, 2018.

(11)                 lebedynskaya EA, Makarenkova ID, Lebedynskaya OV, Akhmatova NK, Zvyagintseva TN, [Effect of sulfated polysaccharides from brown seaweed Laminaria japonica on the morfology of lymfoid organs and functional characteristics of immunocompetent cells], Biomed Khim. 2014 Sep-Oct;60(5):581-90

(12)                Park, Jun-Hyeong et al. “Promoting Wound Healing Using Low Molecular Weight Fucoidan in a Full-Thickness Dermal Excision Rat Model.” Marine drugsvol. 15,4 112. 7 Apr. 2017, doi:10.3390/md15040112.

 

Glucomannan 600 mg

(13)                Joyce K. Keithley, Barbara Swanson, Susan L. Mikolaitis, Mark DeMeo, Janice M. Zeller, Lou Fogg, and Jehan Adamji; Safety and Efficacy of Glucomannan for Weight Loss in Overweight and Moderately Obese Adults; Journal of Obesity; 2013; 2013: 610908.

(14)                Nitesh Sood; William L Baker; Craig I Coleman; Effect of glucomannan on plasma lipid and glucose concentrations, body weight, and blood pressure: systematic review and meta-analysis; The American Journal of Clinical Nutrition, Volume 88, Issue 4, October 2008, Pages 1167–1175, https://doi.org/10.1093/ajcn/88.4.1167.

(15)                Chearskul S, Sangurai S, Nitiyanant W, Kriengsinyos W, Kooptiwut S, Harindhanavudhi T; Glycemic and lipid responses to glucomannan in Thais with type 2 diabetes mellitus; Journal of Medical Association of Thiland; 2007 Oct;90(10):2150-7.

 

Green Coffee Bean Extract

(16) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Jul 12, 2013; Last Updated: Sep 26, 2018; Green Coffee Extract; Examine.com; https://examine.com/supplements/green-coffee-extract/

 

Green Tea 500 mg

(17) Ana Paula Oliveira; Amanda Leite Guimarães; Raimundo Gonçalves de Oliveira Junior; Jullyana Quintans; Camellia sinensis (L.) Kuntze: A Review of Chemical and Nutraceutical Properties; NATURAL PRODUCTS: Research Reviews — Volume 4 —, Edition: 1, Chapter: 2, Publisher: Thomson Press India Limited, Editors: Vijay Kumar Gupta, pp.44.

 

Spirulina Micro-Algae 380 mg

(18) Mansoreh Ghaeni and Laleh Roomiani, " Review for Application and Medicine Effects of Spirulina, Spirulina platensis Microalgae", Journal of Advanced Agricultural Technologies Vol. 3, No. 2, June 2016.

(19) Radha Palaniswamy and Chandra Veluchamy, " THERAPEUTIC USES OF SPIRULINA: A REVIEW", International Journal of Current Innovation Research, Vol. 4, Issue, 1(A), pp. 975-979, January, 2018.

(20) Lisiane Fernandes de Carvalho, Juliana Botelho Moreira et. Al., " Novel Food Supplements Formulated With Spirulina To Meet Athletes’ Needs", Braz. arch. biol. technol. vol.60 Curitiba 2017 Epub Oct 05, 2017.

 

Super CitriMax® (Garcinia cambogia)

(21) https://examine.com/supplements/garcinia-cambogia
(22) Rasha HM, Salha A, Thanai A and Zahar A, " The Biological Importance Of Garcinia Cambogia: A review", J Nutr Food Sci 2015, S5.
(23) Ilma kauser, Syed Zaid naqvi et. Al., "Effects of Camellia sinensis and Garcinia cambogia on obesity & its comorbidities – safer alternative then synthetic drugs", Int. J. Pharm. Sci. Rev. Res., 27(2), July – August 2014; Article No. 54, Pages: 319-327.
(24) Yamada T, Hida H, Yamada Y, " Chemistry, physiological properties, and microbial production of hydroxycitric acid", Appl Microbiol Biotechnol. 2007 Jul;75(5):977-82. Epub 2007 May 3.
(25) Eficiența unui extract nou, natural, pe bază de acid hidroxicitric (HCA-SX) și a combinației de HCA-SX, crom legat la nivel molecular cu niacină și extract de Gymnema sylvestre, în controlul greutății pacienților umani: un studiu pilot. Preuss, Harry G., et al. Nutrition Research 24.1 (2004): 45-58.

  

Sistemul Endocrin

 

Adrenal Vitality™

(1) Meghan Dutt; Ishwarlal Jialal; Physiology, Adrenal Gland; Last Update: January 2, 2019.
(2) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Aug 17, 2014; Last Updated: Jun 14, 2018; Eleutherococcus senticosus; Examine.com; https://examine.com/supplements/eleutherococcus-senticosus/
(3) Assessment report on Eleutherococcus senticosus (Rupr. et Maxim.) Maxim., radix; 25 March 2014; EMA/HMPC/680615/2013; Committee on Herbal Medicinal Products (HMPC).
(4)   Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: May 11, 2014; Last Updated: Oct 1, 2018; Astragalus membranaceus; Examine.com; https://examine.com/supplementshttps://examine.com/supplements/astragalus-membranaceus//astragalus-membranaceus/
(5) William L. Green; Effects of 3-nitro-l-tyrosine on thyroid function in the rat: an experimental model for the dehalogenase defect; Journal of Clinical Investigation; 1971 Dec; 50(12): 2474–2484.

 

Asian Ginseng 560 mg

(3)                  Assessment report on Eleutherococcus senticosus (Rupr. et Maxim.) Maxim., radix; 25 March 2014; EMA/HMPC/680615/2013; Committee on Herbal Medicinal Products (HMPC).

(6) Lesley Braun, Marc Cohen, " Herb& Natural Supplements- An evidence-based guide", 3RD EDITION, Ginseng-Korean pg. 509-524.

 

L-Tyrosine 500 mg

(5) William L. Green; Effects of 3-nitro-l-tyrosine on thyroid function in the rat: an experimental model for the dehalogenase defect; Journal of Clinical Investigation; 1971 Dec; 50(12): 2474–2484.(7) Manualul Merck, Editia a XVIII-a; 2006; Hipotiroidismul; pg. 1200-1203.
(8)https://www.webmd.com/vitamins/ai/ingredientmono-1037/tyrosine

 

Thyroid Caps™

(9) https://www.uofmhealth.org/health-library/hn-2851008
(10) https://ibrainandbody.com/essential-nutrients-for-thyroid-function/
(11) Nussey S, Whitehead S. Endocrinology: An Integrated Approach. Oxford: BIOS Scientific Publishers; 2001. Chapter 3, The thyroid gland. Available from: https://www.ncbi.nlm.nih.gov/books/NBK28.
(12) https://www.mayoclinic.org/diseases-conditions/hypothyroidism/symptoms-causes/syc-20350284

 

Kelp 550 mg

(13) Frithjof C. Küpper,a,b,c,d Lucy J. Carpenter,e Gordon B. McFiggans,f Carl J. Palmer,e,g Tim J. Waite,h Eva-Maria Boneberg,b,i Sonja Woitsch,b Markus Weiller,b Rafael Abela,j Daniel Grolimund,j Philippe Potin,k Alison Butler,c George W. Luther, III,h Peter M. H. Kroneck,b Wolfram Meyer-Klaucke,l and Martin C. Feitersm; Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry; Proceedings of the National Academy of Sciences of the United States of America; 2008 May 13; 105(19): 6954–6958.
(14) Mark L. Wells, Philippe Potin, James S. Craigie, John A. Raven, Sabeeha S. Merchant, Katherine E. Helliwell, Alison G. Smith, Mary Ellen Camire, and Susan H. Brawley; Algae as nutritional and functional food sources: revisiting our understanding; Journal of Applied Phycology; 2017; 29(2): 949–982.
(15) Se-Kwon Kim, Ira Bhatnagar; Advances in Food and Nutrition Research; Marine Medicinal Foods; 2011.

 

Sistem Ocular

 

Lutein Eyes™ Advanced

(1) Roberts JE, Dennison J. The Photobiology of Lutein and Zeaxanthin in the Eye. J Ophthalmol. 2015;2015:687173.
(2) https://www.ema.europa.eu/en/documents/herbal-report/draft-assessment-report-vaccinium-myrtillus-l-fructus_en.pdf
(3) Chu W, Cheung SCM, Lau RAW, et al. Bilberry (Vaccinium myrtillus L.) In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 4.
(4) Aly EM, Ali MA. Effects of bilberry on deoxyribonucleic Acid damage and oxidant-antioxidant balance in the lens, induced by ultraviolet radiation. Malays J Med Sci. 2014;21(1):11–18

 

Ultra Zeaxanthin™

(5) Silvio Buscemi, Davide Corleo, Francesco Di Pace, Maria Letizia Petroni, Angela Satriano, and Giulio Marchesini; The Effect of Lutein on Eye and Extra-Eye Health; Nutrients. 2018 Sep; 10(9): 1321.
(6) Kvansakul J, Rodriguez-Carmona M, Edgar DF, Barker FM, Köpcke W, Schalch W, Barbur JL; Supplementation with the carotenoids lutein or zeaxanthin improves human visual performance; Ophthalmic Physiol Opt. 2006 Jul;26(4):362-71.

 

Diviziune Celulara Normala

 

AHCC® plus NAC & Beta Glucan

(1) https://www.vfbioscience.com/product/ahcc/

(2) Kota Shigama, Akihiro Nakaya et. Al., " Alleviating effect of active hexose correlated compound (AHCC) for anticancer drug-induced side effects in non-tumor-bearing mice", Journal of Experimental Therapeutics and Oncology Vol. 0 2009.

(3) Khawaja Muhammad, Imran Bashir and Jae-Suk Choi, " Clinical and Physiological Perspectives of β-Glucans: The Past, Present, and Future", Int J Mol Sci. 2017 Sep; 18(9): 1906.

(4) She-FangYea, Kaoru Ichimura et. Al., " Suppressive effects of Active Hexose Correlated Compound on the increased activity of hepatic and renal ornithine decarboxylase induced by oxidative stress",Life Sciences, Volume 74, Issue 5, 19 December 2003, Pages 593-602

(5) Dan Kenner, Ph.D., L.Ac., " Treatment for Immune Dysfunction from Post-Traumatic Stress Disorder and Chronic Disease with AHCC", Townsend Letter For Doctors, Dec. 2001, pp 68-72.

(6) Randy A. Sansone,Lori A. Sansone, " Getting a Knack for NAC", Innov Clin Neurosci. 2011 Jan; 8(1): 10–14

 

Beta Glucan 200 mg

(3) Khawaja Muhammad, Imran Bashir and Jae-Suk Choi, " Clinical and Physiological Perspectives of β-Glucans: The Past, Present, and Future", Int J Mol Sci. 2017 Sep; 18(9): 1906.

 

Cordyceps

(7) Hui-Chen Lo, Chienyan Hsieh, Fang-Yi Lin, and Tai-Hao Hsu; A Systematic Review of the Mysterious Caterpillar Fungus Ophiocordyceps sinensis in Dong-ChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo) and Related Bioactive Ingredients; Journal of Traditional and Complementary Medicine; 2013 Jan-Mar; 3(1): 16–32; doi: 10.4103/2225-4110.106538.

 

Curcumin 95 500 mg

(8) Gaurisankar S. and Tanya Das; Anti cancer effects of curcumin: cycle of life and death; Cell Division. 2008; 3: 14; Published online 2008 Oct 3. doi: 10.1186/1747-1028-3-14.
(9) Susan J. Hewlings and Douglas S. Kalman; Curcumin: A Review of Its’ Effects on Human Health; Foods. 2017 Oct; 6(10): 92; Published online 2017 Oct 22. doi: 10.3390/foods6100092.
(10) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Feb 5, 2015; Last Updated: May 27, 2019; Curcumin; Examine.com; https://examine.com/supplements/curcumin/#oxidation-and-anti-oxidation

 

Curcumin Phytosome 500 mg

(8) Gaurisankar S. and Tanya Das; Anti cancer effects of curcumin: cycle of life and death; Cell Division. 2008; 3: 14; Published online 2008 Oct 3. doi: 10.1186/1747-1028-3-14.
(9) Susan J. Hewlings and Douglas S. Kalman; Curcumin: A Review of Its’ Effects on Human Health; Foods. 2017 Oct; 6(10): 92; Published online 2017 Oct 22. doi: 10.3390/foods6100092.
(10) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Feb 5, 2015; Last Updated: May 27, 2019; Curcumin; Examine.com; https://examine.com/supplements/curcumin/#oxidation-and-anti-oxidation

 

Essiac®

(11) Ali E Al-Snafi; Department of Pharmacology, College of Medicine, Thi qar University, Nasiriyah, P O Box 42, Iraq; Manuscript No: IJPRS/V3/I1/00115, Received On: 09/03/2014, Accepted On: 17/03/2014; The Pharmacological Importance and Chemical Constituents of Arctium Lappa; A Review; International Journal for Pharmaceutical Research Scholars (IJPRS).
(12) Andrea Vasas; Orsolya Orbán-Gyapai; JuditHohmann; The Genus Rumex: Review of traditional uses, phytochemistry and pharmacology; Journal of Ethnopharmacology; Volume 175, 4 December 2015, Pages 198-228.
(13) Lesley Braun, Marc Cohen; Herbs and Natural Supplements, An evidence based guide, 3rd Edition; 2010; Churchill Livingstone, Elsevier; Slippery Elm; pg. 864-866.

 

IP6 500 mg

(14) Colodny L1, Hoffman RL; Inositol--clinical applications for exogenous use; Alternative Medicine Review; 1998 Dec;3(6):432-47.
(15) Maeba R, et al. Myo-inositol treatment increases serum plasmalogens and decreases small dense LDL, particularly in hyperlipidemic subjects with metabolic syndrome . J Nutr Sci Vitaminol (Tokyo), 2008.
(16) Pizzo A, Laganà AS, Barbaro L. Comparison between effects of myo-inositol and D-chiro-inositol on ovarian function and metabolic factors in women with PCOS. Gynecol Endocrinol 2014;30(3):205-8.

 

Maitake D-fraction®

(17) Eliana Noelia Alonso, María Julia Ferronato, Norberto Ariel Gandini, María Eugenia Fermento, Diego Javier Obiol, Alejandro López Romero, Julián Arévalo, María Emilia Villegas, María Marta Facchinetti & Alejandro Carlos Curino; Antitumoral Effects of D-Fraction from Grifola Frondosa (Maitake) Mushroom in Breast Cancer; Journal of Nutrition and Cancer; Volume 69, 2017 - Issue 1; Pages 29-43 | Received 26 Nov 2015, Accepted 04 Aug 2016, Published online: 28 Nov 2016.
(18) Xirui He, Xiaoxiao Wang, Jiachen Fang, Yu Chang, Ning Ning, Hao Guo, Linhong Huan, Xiaoqiang Huang, Zefeng Zhao; Polysaccharides in Grifola frondosa mushroom and their health promoting properties: A review; International Journal of Biological Macromolecules; Volume 101, August 2017, Pages 910-921.

 

Reishi SE 188mg

(21) Jiang J, Slivova V, Valachovicova T, Harvey K, Sliva D; Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3; International Journal of Oncology; 2004 May;24(5):1093-9.
(22) Sissi Wachtel-Galor, John Yuen, John A. Buswell, and Iris F. F. Benzie; Chapter 9Ganoderma lucidum (Lingzhi or Reishi); A Medicinal Mushroom; Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition; Benzie IFF, Wachtel-Galor S, editors; Boca Raton (FL): CRC Press/Taylor & Francis; 2011.

 

SOD 2000 Plus™

(11) Ali E Al-Snafi; Department of Pharmacology, College of Medicine, Thi qar University, Nasiriyah, P O Box 42, Iraq; Manuscript No: IJPRS/V3/I1/00115, Received On: 09/03/2014, Accepted On: 17/03/2014; The Pharmacological Importance and Chemical Constituents of Arctium Lappa; A Review; International J ournal for Pharmaceutical Research Scholars (IJPRS).
(23) Bagchi D, Garg A, Krohn RL, Bagchi M, Tran MX, Stohs SJ; Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro; Research Communication in Molecular Pathology and Pharmacology; 1997 Feb; 95(2):179-89.
(24) Igor Y. Iskusnykh, Tatyana N. Popova, Aleksander A. Agarkov, Miguel Â. A. Pinheiro de Carvalho, and Stanislav G. Rjevskiy; Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats; Journal of Toxicology; 2013; 2013: 870628.

 

Super Coriolus

(25) Heidi Fritz, ND, MA, Deborah A. Kennedy, MBA, ND, PhD, Mami Ishii, BM, MT-BC, Dean Fergusson, PhD, Rochelle Fernandes, MSc, Kieran Cooley, ND, Dugald Seely, ND, MSc, FABNO; Polysaccharide K and Coriolus versicolor Extracts for Lung Cancer: A Systematic Review; Integrative Cancer Therapies; First Published March 17, 2015; https://doi.org/10.1177/1534735415572883
(26) Mohammad H. Saleh; Iran Rashedi and Armand Keating; Immunomodulatory Properties of Coriolus versicolor: The Role of Polysaccharopeptide; Frontiers in Immunology. 2017; 8: 1087; Published online 2017 Sep 6. doi: 10.3389/fimmu.2017.01087.

 

Super Royal Agaricus

(27) Geir Hetland, Egil Johnson, Torstein Lyberg and Gunnar Kvalheim; The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation; Advances in Pharmacological Science; 2011: 157015.
(28) Hang Wang, Zhiming Fu, and Chunchao Han; The Medicinal Values of Culinary-Medicinal Royal Sun Mushroom (Agaricus blazei Murrill); Evidence-Based Complementary and Alternative Medicine; 2013; 2013: 842619; Published online 2013 Oct 31. doi: 10.1155/2013/842619.
(29) F. Firenzuoli, L. Gori,1 and G. Lombardo; The Medicinal Mushroom Agaricus blazei Murrill: Review of Literature and Pharmaco-Toxicological Problems; Evidence-Based Complementary and Alternative Medicine; 2008 Mar; 5(1): 3–15; Published online 2007 Mar 27. doi: 10.1093/ecam/nem007.
(30) Linda K Ellertsen and Geir Hetlandcorresponding; An extract of the medicinal mushroom Agaricus blazei Murill can protect against allergy; Clin Mol Allergy. 2009; 7: 6.Published online 2009 May 5. doi: 10.1186/1476-7961-7-6.

 

Tien Hsien Liquid

(21) Jiang J, Slivova V, Valachovicova T, Harvey K, Sliva D; Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3; International Journal of Oncology; 2004 May;24(5):1093-9.
(31) *Studiu clinic efectuat pe produsul natural complementar Tien Hsien Liquid: Efectele Tien Hsien Liquid la pacienţii cu cancer de sân metastazat, refractar la terapiile convenţionale.

 

Super Poria

(32)https://www.hindawi.com/journals/jchem/2021/6659775/?utm_source=google&utm_medium=cpc&utm_campaign=HDW_MRKT_GBL_SUB_ADWO_PAI_DYNA_SPEC_X_X0000_Oct2023&gad_source=1&gclid=EAIaIQobChMItbDnxMH2ggMVaERBAh3yrw34EAMYASAAEgKJ1_D_BwE
(33) https://pubmed.ncbi.nlm.nih.gov/12569111/
(34) https://onlinelibrary.wiley.com/doi/10.1111/jcmm.13564
(35) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824143/
(36) https://www.verywellhealth.com/the-benefits-of-poria-88643

 

Super Meshima

(37) https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-021-05740-5
(38) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445909/
(39) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572527/
(40) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445909/
(41) https://www.mdpi.com/1420-3049/24/10/1888
(42) https://pubmed.ncbi.nlm.nih.gov/32751371/
(43) https://www.sciencedirect.com/science/article/abs/pii/S0006291X15300905?via%3Dihub
(44) https://www.nature.com/articles/6604319

 

Super Chaga

(45) https://www.medicalnewstoday.com/articles/318527
(46) https://www.healthline.com/nutrition/chaga-mushroom#side-effects
(47) https://www.indigo-herbs.co.uk/natural-health-guide/benefits/chaga-mushroom
(48) https://forestspafinland.com/blogs/forestspafinlandstory/chaga-mushrooms-what-are-the-benefits-of-these-adaptogenic-plants
(49) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124789/
(50) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625788/

 

Echilibru Hormonal

Subsegment: Sănătatea organismului feminin

 

Black Cohosh

(1) Lesley Braun, Marc Cohen; Herbs and Natural Supplements; An evidence-based guide, 3rd Edition; Churchill Livingstone, Elsevier, 2010; pg. 256-262; Black cohosh.

 

Female Hormone Blend SP-7C™

(1) Lesley Braun, Marc Cohen; Herbs and Natural Supplements; An evidence-based guide, 3rd Edition; Churchill Livingstone, Elsevier, 2010; pg. 256-262; Black cohosh.
(2) Assessment report on Angelica sinensis (Oliv.) Diels, radix; 9 July 2013; EMA/HMPC/614586/2012; Committee on Herbal Medicinal Products (HMPC).
(3) Lesley Braun, Marc Cohen; Herbs and Natural Supplements; An evidence-based guide, 3rd Edition; Churchill Livingstone, Elsevier, 2010; pg. 782-784: Raspberry leaf.
(4) Patrícia de Souza Bonfim-Mendonça, Isis Regina Grenier Capoci, Flávia Kelly Tobaldini-Valerio, Melyssa Negri, and Terezinha Inez Estivalet Svidzinski; Overview of β-Glucans from Laminaria spp.: Immunomodulation Properties and Applications on Biologic Models; International Journal of Molecular Science; 2017 Sep; 18(9): 1629; Published online 2017 Sep 6

 

Fenugreek (Schinduf) 610 mg

(16) Sajad AhmadWani, PradyumanKumar, ˝ Fenugreek: A review on its nutraceutical properties and utilization in various food products˝, Journal of the Saudi Society of Agricultural Sciences, Volume 17, Issue 2, April 2018, Pages 97-106.
(17) https://www.healthline.com/nutrition/fenugreek#bottom-line
(18) Sima Younesy, Sedigheh Amiraliakbari et. Al., ˝ Effects of Fenugreek Seed on the Severity and Systemic Symptoms of Dysmenorrhea˝, J Reprod Infertil. 2014 Jan-Mar; 15(1): 41–48.

 

Dong Quai 565 mg

(2) Assessment report on Angelica sinensis (Oliv.) Diels, radix; 9 July 2013; EMA/HMPC/614586/2012; Committee on Herbal Medicinal Products (HMPC).

 

Indole-3 Supreme™

(5) Jay H. Fowke, Christopher Longcope and James R. Hebert; Brassica Vegetable Consumption Shifts Estrogen Metabolism in Healthy Postmenopausal Women; Cancer Epidemiology, Biomarkers and Prevention; Published August 2000.
(6) Jing-Ru Weng, Chen-HsunTsai, Samuel K.Kulp, Ching-Shih Chen; Indole-3-carbinol as a chemopreventive and anti-cancer agent; Cancer Letters; Volume 262, Issue 2, 18 April 2008, Pages 153-163.

 

Licorice (Lemn-dulce) 450 mg

(7) https://www.webmd.com/vitamins/ai/ingredientmono-881/licorice
(8) Parsa Ravanfar, Golnaz Namazi, Afshin Borhani-Haghighi, Shaghayegh Zafarmand; Neurologic effects of licorice: A review; PLANT REVIEW; Year : 2018 | Volume : 12 | Issue : 23 | Page : 115-119.

 

PreMenstrual Solution™

(2)    Assessment report on Angelica sinensis (Oliv.) Diels, radix; 9 July 2013; EMA/HMPC/614586/2012; Committee on Herbal Medicinal Products (HMPC).
(7)    https://www.webmd.com/vitamins/ai/ingredientmono-881/licorice
(8)    Parsa Ravanfar, Golnaz Namazi, Afshin Borhani-Haghighi, Shaghayegh Zafarmand; Neurologic effects of licorice: A review; PLANT REVIEW; Year : 2018 | Volume : 12 | Issue : 23 | Page : 115-119

 

Red Clover (Trifoi-rosu) 400 mg

(9)  Catherine Ulbricht, PharmD, Column Editor, " Red Clover (Trifolium pratense) Monograph:A Clinical Decision Support Tool", Journal of Herbal Pharmacotherapy, Vol. 2(3) 2002http://www.haworthpressinc.com/store/product.asp?sku=J157 2002 by The Haworth Press, Inc.
(10)  Kelly, G., A. Husband, and M. Waring., " Standardized Red Clover" Extract Clinical Monograph. Natural Products Research Consultants, Inc., Seattle, WA 98104. 1998.

 

Vitex 400 mg

(11) https://www.romedic.ro/cauze-hormonale-de-infertilitate-la-femei-0P19084/ https://www.romedic.ro/cauze-hormonale-de-infertilitate-la-barbati-0P19231
(12) Mina Cheraghi Niroumand, Fatemeh Heydarpour, Mohammad Hosein Farzaei, " Pharmacological and therapeutic effects of Vitex agnus-castus L.: A review", Pharmacognosy Review, 2018, Volume 12, Page: 103-114
(13) Pasquale De Franciscis, Flavio Grauso et. Al., " Adding Agnus Castus and Magnolia to Soy Isoflavones Relieves Sleep Disturbances Besides Postmenopausal Vasomotor Symptoms-Long Term Safety and Effectiveness", Nutrients. 2017 Feb; 9(2): 129

 

Wild Yam 425 mg

(14) Lesley Braun, Marc Cohen, " Herb& Natural Supplements- An evidence-based guide", 3RD EDITION, Wild Yam, pages: 1024-1025
(15) Dioscorea villosa Wild Yam Monograph, DECEMBER 13, 2017, https://bearalchemy.com/wild-yam-monograph/

 

Methyl Folate 400 mcg

(19) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380836/ -
(20) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085763/
(21) https://www.revistagalenus.ro/practica-medicala/homocisteina-si-mutatiile-mthfr-2 -
(22) https://www.medichub.ro/reviste/psihiatru-ro/implicatiile-polimorfismelor-genei-mthfr-in-etiologia-schizofreniei-id-(1107-cmsid-66
(23) https://quatrefolic.com
(24) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616856/
(25) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509461/
(26) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218540/
(27) https://pubmed.ncbi.nlm.nih.gov/15129193/-
(28) https://www.sciencedirect.com/science/article/pii/S0022316622153848?via%3Dihub -
(29) https://pubmed.ncbi.nlm.nih.gov/18950248/
(30) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953465/-
(31) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520042/
(32) https://www.sciencedirect.com/science/article/pii/S2405844023054324
(33) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161099/-
(34) https://pubmed.ncbi.nlm.nih.gov/21170581/-
(35) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262611/
(36) https://www.sciencedirect.com/science/article/abs/pii/0002934382904065
(37) https://www.healthline.com/health/folate-deficiency#risk-factors

 

Subsegment: Sănătatea organismului masculin

 

Men's Power

(1) A. Barassi, M.M. Corsi Romanelli et. Al., " Levels of L-arginine and L-citrulline in patients with erectile dysfunction of different etiology", American Society of Andrology, 2017, 5, 256-261.
(2) https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/symptoms-causes/syc-20355776
(3) R. Estrada-Reyes, M. Carro-Juarez, L. Martınez-Mota, Pro-sexual effects of Turnera diffusa Wild (Turneraceae) in male rats involves the nitric oxide pathway, Journal of Ethnopharmacology, Journal of Ethnopharmacology 146 (2013) 164–172
(4) Lee MS, Lee HW, You S, Ha KT, The use of maca (Lepidium meyenii) to improve semen quality: A systematic review, Maturitas. 2016 Oct;92:64-69
(5) Tripathi, Pratima et al. “Role of l-Arginine on Dyslipidemic Conditions of Acute Myocardial Infarction Patients.” Indian journal of clinical biochemistry : IJCB vol. 27,3 (2012): 296-9. doi:10.1007/s12291-012-0188-9
(6) H Tapieroa, G Mathé, P Couvreur, K.D Tew, " I. Arginine", Biomedicine & Pharmacotherapy Volume 56, Issue 9, November 2002, Pages 439-445.
(7) https://nutritionreview.org/2013/04/arginine-select-phytonutrients-enhance-libido/

 

Nettle Root (Urzică)

(8) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team; Published: Aug 4, 2014; Last Updated: Jun 14, 2018; Stinging Nettle; Examine.ro; https://examine.com/supplements/stinging-nettle/

 

Prostate Blend SP-16™

(8) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team; Published: Aug 4, 2014; Last Updated: Jun 14, 2018; Stinging Nettle; Examine.ro; https://examine.com/supplements/stinging-nettle/
(9) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team; Published: Jan 27, 2015; Last Updated: Jun 14, 2018; Saw Palmetto; Examine.com; https://examine.com/supplements/saw-palmetto/

 

Saw Palmetto

(9) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team; Published: Jan 27, 2015; Last Updated: Jun 14, 2018; Saw Palmetto; Examine.com; https://examine.com/supplements/saw-palmetto/

 

Tribulus Fruit Extract 450 mg

(10) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623187/
(11) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850326/
(12)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277861/
(13) https://pubmed.ncbi.nlm.nih.gov/30888914/
(14) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054192/
(15) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368143/
(16) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931200/
(17) https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/tribulus
(18) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225498/
(19) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407028/
(20) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647001/
(21) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504392/
(22) https://www.revistagalenus.ro/arhiva/revista-galenus-2010/tribulus-terrestris-specii-medicinale-putin-cunoscute-in-romania-xxiv/

 

Muira Puama 300 mg

(23) https://www.rain-tree.com/muirapuama.htm
(24) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340557/
(25) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422695/
(26) https://nutrientjournal.com/muira-puama-may-enhance-sexual-cognitive-performance/
(27) https://pubmed.ncbi.nlm.nih.gov/11186145/
(28)https://www.frontiersin.org/articles/10.3389/fphar.2021.644103/full?fbclid=IwAR0rU0SHCCgCZFTzt__yOkQa0uqkbFTOVT4r2C5nDo2Ok9FTnuxGF4VSb5c
(29) https://pubmed.ncbi.nlm.nih.gov/19095451/
(30) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911531/
(31)  https://www.indigo-herbs.co.uk/natural-health-guide/benefits/muira-puama

 

Subsegment: Fertilitate masculină și feminina

 

Hormone Blend SP-1™

(4) Johanna Willer, Karin Jöhrer et. Al., " Cytotoxic Properties of Damiana (Turnera diffusa) Extracts and Constituents and A Validated Quantitative UHPLC-DAD Assay", Molecules 2019, 24(5), 855; https://doi.org/10.3390/molecules24050855.
(5) TERESA BAILEY KLEPSER AND MICHAEL E. KLEPSER, " Unsafe and potentially safe herbal therapies", Vol 56 Jan 15 1999 Am J Health-Syst Pharm.
(6) https://restorativemedicine.org/library/monographs/oarweed/
(7) Eleutherococcus senticosus, Alternative Medicine Review u Volume 11, Number 2 u 2006bn.
(8) Zava DT1, Dollbaum CM, Blen M., " Estrogen and progestin bioactivity of foods, herbs, and spices", Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78.
(9) https://www.medicalnewstoday.com/articles/322513.php

 

Inositol 750 mg

(10) https://examine.com/supplements/inositol/
(11) Marine L. Croze, Christophe O. Soulage, " Potential role and therapeutic interests of myo-inositol in metabolic diseases", Biochimie 95(2013), 1811-1827.
(12) Lisa Colodny, Pharm D. and Ronald L. Hoffman, M.D., " Inositol – Clinical Applications for Exogenous Use", Alternative Medicine Review; Volume 3, Number 6; 1998.
(13) A. E. Calogero, G. Gullo et. Al., " Myoinositol improves sperm parameters and serum reproductive hormones in patients with idiopathic infertility: a prospective double‐blind randomized placebo‐controlled study", Andrology, 2015, 3, 491–495.

 

Maca SE

(1) H. O. Meissner, H. Reich-Bilinska et. Al., " Therapeutic Effects of Pre-Gelatinized Maca (Lepidium Peruvianum Chacon) used as a Non-Hormonal Alternative to HRT in Perimenopausal Women - Clinical Pilot Study", Int J Biomed Sci. 2006 Jun; 2(2): 143–159.
(2) Zhong Ai, Ai-Fang Cheng et. Al., " Antidepressant-Like Behavioral, Anatomical, and Biochemical Effects of Petroleum Ether Extract from Maca (Lepidium meyenii) in Mice Exposed to Chronic Unpredictable Mild Stress", J Med Food. 2014 May 1; 17(5): 535–542.
(3) Gustavo F. Gonzales, " Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands", Evid Based Complement Alternat Med. 2012; 2012: 193496.

 

Pomegranate (Rodie)

(14) Julie Jurenka, MT (ASCP), " Therapeutic Applications of Pomegranate (Punica granatum L.): A Review", Alternative Medicine Review Volume 13, Number 2 2008.
(15) Prasan R Bhandari, " Pomegranate (Punica granatum L). Ancient seeds for modern cure? Review of potential therapeutic applications", International Journal of Nutrition, Pharmacology, Neurological Diseases, 2012, Volume 2, Page : 171-184.
(16) Sreeja Sreekumar, Hima Sithul et. Al., " Pomegranate Fruit as a Rich Source of Biologically Active Compounds",Biomed Res Int. 2014; 2014: 686921.

 

Sistemul Respirator

 

L-Cysteine 500 mg

(1) Noelia Clemente Plaza, Manuel Reig García-Galbis et. Al., "Effects of the Usage of L-Cysteine (L-Cys) on Human Health", Molecules 2018,23, 575; doi:10.3390/molecules23030575
(2) Elvin Harper , Sam Seifter, "Studies on the Mechanism of Action of Collagenase: Inhibition by Cysteine and Other Chelating Agents", Israel Journal of Chemestry

 

No Snorz™

(3) Paul M. Coates, Joseph M. Betz et. Al., " Encyclopedia of Dietary Supplements", 2nd Edition, Published June 25, 2010.
(4) Krishnapura Srinivasan, "Biological Activities of Red Pepper (Capsicum annuum) and Its Pungent Principle Capsaicin: A Review", Journal Critical Reviews in Food Science and Nutrition, Volume 56, 2016 - Issue 9.
(5) Mrs. Vishin A. Patil , Mr. Sachin A. Nitave, " A REVIEW ON EUCALYPTUS GLOBULUS: A DIVINE MEDICINAL HERB", WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, Volume 3, Issue 6, 559-567.
(6) Tarek Gharibeh and Reena Mehra, " Obstructive sleep apnea syndrome: natural history, diagnosis, and emerging treatment options", Nat Sci Sleep. 2010; 2: 233–255



Quercetin 500 mg

(7) Abigail J. Larson J. David Symons et. Al., " Therapeutic Potential of Quercetin to Decrease Blood Pressure: Review of Efficacy and Mechanisms", Advances in Nutrition, Volume 3, Issue 1, January 2012, Pages 39–46.
(8) Gregory S. Kelly, ND, " Quercetin", Alternative Medicine review, Volume 16, Number 2.
(9) Lesley Braun, Marc Cohen, " Herb& Natural Supplements- An evidence-based guide", 3RD EDITION, Quercetin pg. 774-782.

 

Respiratory Protect Capsules

(10) Younes Najafian, Shokouh Sadat Hamedi, Masoumeh Kaboli Farshchi, and Zohre Feyzabadi; Plantago major in Traditional Persian Medicine and modern phytotherapy: a narrative review; Electronic Physician. 2018 Feb; 10(2): 6390–6399.
(11) Felix Holzinger, Jean-François Chenot, “ Systematic Review of Clinical Trials Assessing the Effectiveness of Ivy Leaf (Hedera Helix) for Acute Upper Respiratory Tract Infections”, Volume 2011 | Article ID 382789 | https://doi.org/10.1155/2011/382789
(12) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534447/
(13) Anwarul‐Hassan Gilani; Najeeb‐ur Rehman; Aslam Khan; Khalid M. Alkharfy; Studies on Bronchodilator Activity of Salvia officinalis (Sage): Possible Involvement of K+ Channel Activation and Phosphodiesterase Inhibition; Phytotherapy Research; First published: 01 June 2015.
(14) Ângelo C. Salvador, Armando J. D. Silvestre and Sílvia M. Rocha; Comprehensive Insight into the Elderflowers and Elderberries (Sambucus nigra L.) Mono and Sesquiterpenic Metabolites: Factors that Modulate Their Composition; Chapter 4; 2018.
(15) Rashmi Gaur Vivek Kumar Gupta Pooja Singh Anirban Pal Mahendra Padurang Darokar Rajendra Singh Bhakuni; Drug Resistance Reversal Potential of Isoliquiritigenin and Liquiritigenin Isolated from Glycyrrhiza glabra Against Methicillin‐Resistant Staphylococcus aureus (MRSA); Phytotherapy Research; 08 July 2016.
(16) John R. Arthur, Roderick C. McKenzie et. All., “ Selenium in the Immune System”, The Journal of Nutrition Volume 133, Issue 5, May 2003, Pages 1457S-1459S.

(17) Martina Maywald; LotharRink; Zinc homeostasis and immunosenescence; Journal of Trace Elements in Medicine and Biology; Volume 29, January 2015, Pages 24-30.
(18) Ajaikumar B. Kunnumakkara, Kishore Banik, Devivasha Bordoloi, Choudhary Harsha, Bethsebie L. Sailo, Ganesan Padmavathi, Nand K. Roy, Subash C. Gupta, and Bharat B. Aggarwal; Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases; Frontiers in Pharmacology. 2018; 9: 686; Published online 2018 Aug 6. doi: 10.3389/fphar.2018.00686.

 

Daily-Quercetin 500 mg

(19) Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi:10.3390/molecules24061123
(20) Bentz A.B., A Review of Quercetin: Chemistry, Antioxidant Properties, and Bioavailability
(21) Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):84-89. doi:10.4103/0973-7847.194044
(22) Saeedi-Boroujeni, A., Mahmoudian-Sani, MR. Anti-inflammatory potential of Quercetin in COVID-19 treatment. J Inflamm 18, 3 (2021). https://doi.org/10.1186/s12950-021-00268-6
(23) Mlcek J, Jurikova T, Skrovankova S, Sochor J. Quercetin and Its Anti-Allergic Immune Response. Molecules. 2016;21(5):623. Published 2016 May 12. doi:10.3390/molecules21050623
(24) Wu W, Li R, Li X, et al. Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry. Viruses. 2015;8(1):6. Published 2015 Dec 25. doi:10.3390/v8010006
(25) Kinker B, Comstock AT, Sajjan US (2014) Quercetin: A Promising Treatment for the Common Cold. J Anc Dis Prev Rem 2: 111
(26) Ay, Muhammet & Charli, Adhithiya & Jin, Huajun & Anantharam, Vellareddy & Kanthasamy, Arthi & Kanthasamy, Anumantha. (2016). Quercetin. 10.1016/B978-0-12-802147-7.00032-2
(27) Qian Deng, Xiao Xue Li, Yanting Fang, Xin Chen, Jingui Xue, "Therapeutic Potential of Quercetin as an Antiatherosclerotic Agent in Atherosclerotic Cardiovascular Disease: A Review", Evidence-Based Complementary and Alternative Medicine, vol. 2020, Article ID 5926381, 12 pages, 2020
(28) Lin R, Piao M and Song Y (2019) Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in Citrobacter rodentium-Infected Mice. Front. Microbiol. 10:1092. doi: 10.3389/fmicb.2019.01092

 

Cold-Care Cough Syrup

(29)https://archivepp.com/storage/models/article/YqwXaQqt0YLt4E3Wws0FJoo5FaUEoBQKaMSdBOIz4c6wg2MthMGABfakVZ13/a-pilot-study-of-efficacy-and-safety-of-plantago-lanceolata-and-primula-veris-in-the-treatment-of-.pdf
(30) https://pubmed.ncbi.nlm.nih.gov/18646148/
(31) https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/grindelia
(32) https://karger.com/cmr/article-abstract/27/3/174/67787/Marsh-Mallow-Althaea-officinalis-L-and-Its-Potency
(33) https://all-imm.com/index.php/aei/article/download/71/524/2549
(34) https://www.gaiaherbs.com/blogs/seeds-of-knowledge/pelargonium-sidoides
(35) https://www.tandfonline.com/doi/full/10.1080/13880200600714137
(36) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424313/
(37) https://www.sciencedirect.com/science/article/abs/pii/S0166354212000642
(38) https://pubmed.ncbi.nlm.nih.gov/33209511/
(39) https://pubmed.ncbi.nlm.nih.gov/33209511/
(40) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175146/
(41) https://www.sciencedirect.com/science/article/abs/pii/B978032384676900074X

 

Cold-Care Hot Drink

(30) https://pubmed.ncbi.nlm.nih.gov/18646148/
(34) https://www.gaiaherbs.com/blogs/seeds-of-knowledge/pelargonium-sidoides
(35) https://www.tandfonline.com/doi/full/10.1080/13880200600714137
(37) https://www.sciencedirect.com/science/article/abs/pii/S0166354212000642
(38) https://pubmed.ncbi.nlm.nih.gov/33209511/
(42) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441164/
(43) https://journals.sagepub.com/doi/pdf/10.1177/15648265090301S104
(44) https://www.sciencedirect.com/science/article/pii/S1818087614000348

 

Sistemul Uro-Genital

 

Asparagus (Sparanghel)

(1) Muhammad Iqbal, Yamin Bibi et. Al., "Review on Therapeutic and Pharmaceutically Important Medicinal Plant Asparagus officinalis L", Journal of Plant Biochemistry & Physiology, Iqbal et al., J Plant Biochem Physiol 2017, 5:1
(2) MieNishimura, TatsuyaOhkawara et. Al., " Improvement of Blood Pressure, Glucose Metabolism, and Lipid Profile by the Intake of Powdered Asparagus (蘆筍 Lú Sǔn) Bottom-stems and Cladophylls", Journal of Traditional and Complementary Medicine, Volume 3, Issue 4, October–December 2013, Pages 250-255

 

Candida Cleanse

(3) Sameh Soliman, Dina Alnajdy et. Al., " Plants’ Natural Products as Alternative Promising Anti-Candida Drugs", Pharmacogn Rev. 2017 Jul-Dec; 11(22): 104–122.
(4) Amy R. Lomax* and Philip C. Calder, "Prebiotics, immune function, infection and inflammation: a review of the evidence", British Journal of Nutrition (2009), 101, 633–658
(5) Mohammad Hosein Farzaei, Zahra Abbasabadi, "Parsley: a review of ethnopharmacology, phytochemistry and bio-logical activities", J Tradit Chin Med 2013 December 15; 33(6): 815-826
(6) Farzaneh Ebrahimy, Mahrokh Dolatian et. Al., ˝Comparison of the therapeutic effects of Garcin® and fluconazole on Candida vaginitis˝, Singapore Med J. 2015 Oct; 56(10): 567–572.

 

CranRx®

(7) Sikandar Khan Sherwani, Asia Neelam et. Al., " MEDICINAL VALUE OF VACCINIUM MACROCARPON (CRANBERRY): A MINI REVIEW", World Journal of Pharmaceutical Research, Volume 3, Issue 6, 71-79.
(8) Nataly Simões Bandiera Thimóteo, Bruna Miglioranza Scavuzzi et. Al., " The impact of cranberry (Vacciniummacrocarpon) and cranberry productson each component of the metabolicsyndrome: a review", Thimóteo et al. Nutrire (2017) 42:25

 

Uro-Care with CranActin®

(9) L. DOMENICI, M. MONTI, C. BRACCHI, M. GIORGINI, V . COLAGIOVANNI, L. MUZII, P . BENEDETTI PANICI; D-mannose: a promising support for acute urinary tract infections in women. A pilot study; European Review for Medical and Pharmacological Sciences; 2016;20:2920-2925.
(10) Francesco Montorsia, Giorgio Gandaglia, Andrea Salonia, Alberto Briganti, Vincenzo Mirone; Effectiveness of a Combination of Cranberries, Lactobacillus rhamnosus, and Vitamin C for the Management of Recurrent Urinary Tract Infections in Women: Results of a Pilot Study; European Urology; December 2016Volume 70, Issue 6, Pages 912–915.
(11) Inventors: Edward B. Walker; Richard A; Mickelsen, Jr.; Jennifer N. Mickelsen; all of Ogden, Utah; CRANBERRY EXTRACT AND BOLOGICALLY ACTIVE COMPOUNDS DERVED THEREFROM; https://patentimages.storage.googleapis.com/a8/74/f0/309a613e649c31/US5646178.pdf
(12) National Institute for Health and Care Excellence; Urinary tract infection (recurrent): antimicrobial prescribing guideline; Evidence review; April 2018; https://www.nice.org.uk/guidance/ng112/documents/evidence-review

 

Kidney Blend™

(13) Ahmed Salih Sahib, ImadHashim Mohammed, Saba JasimHamdan; Use of aqueous extract of corn silk in the treatment of urinary tract infection; Journal of Intercultural Ethnopharmacology; 2012; 1(2):93-96.
(14) Faruk Hassan Al-Jawad ; Rafi Abdul Majeed Al-Razzuqi ; Zainab Awaen Al-Ebady ; Thulfuqar Abdul Majeed Al-Razzuqi; Nephroprotective effect of Corn Silk extract on oxalic acid-induced nephrocalcinosis in rabbit model; Journal of Intercultural Ethnopharmacology; 2012.

 

Uro-Care Litho Cleanse

(15) Mohammad Hosein Farzaei, Zahra Abbasabadi, Mohammad Reza Shams Ardekani, Roja Rahimi, FatemehFarzaei; Parsley: a review of ethnopharmacology, phytochemistry and bio-logicalactivities; Journal of Traditional Chinese Medicine; 2013 December 15; 33(6): 815-826.
(16) Research analysis lead by Kamal Patel; All content reviewed by Examine.com Team. Published: Aug 18, 2014; Last Updated: Jun 14, 2018; Taraxacum officinale; https://examine.com/supplements/taraxacum-officinale/
(17) Research analysis lead by Kamal Patel; All content reviewed by Examine.com Team; Published: Aug 4, 2014; Last Updated: Jun 14, 2018; Stinging Nettle; https://examine.com/supplements/stinging-nettle/

 

Total Cleanse™ Uric Acid

(18) Haidari F Jr, Mohammad Shahi M, Keshavarz SA, Rashidi MR; Inhibitory Effects of Tart Cherry (Prunus cerasus) Juice on Xanthine Oxidoreductase Activity and its Hypouricemic and Antioxidant Effects on Rats; Malaysian Journal of Nutrition, 2009 Mar;15(1):53-64. Epub 2009 Mar 15.
(19) XINLIN WU, JIANXIANG LIU, JIANQING ZHANG, HENG LIU, MIANSHENG YAN, BIRONG LIANG, HONGBO XIE, SHIJUN ZHANG, BAOGUO SUN and HOUMING ZHOU; Folic acid reverses uric acid crystal-induced surface OAT1 internalization by inhibiting RhoA activity in uric acid nephropathy; Molecular Medicine Reports; 2016 Mar; 13(3): 2385–2392.
(20) David Hoffmann, FNIMH, AHG; MEDICAL HERBALISM; THE SCIENCE AND PRACTICE OF HERBAL MEDICINE; 2016; Gout; pg. 426-427.
(21) Research analysis lead by Kamal Patel; All content reviewed by Examine.com Team. Published: Feb 5, 2015; Last Updated: Feb 27, 2019; Curcumin; Examine.com; https://examine.com/supplements/curcumin/

 

Comfort-U® 10 caps veg (DRcaps)

(22) https://pubmed.ncbi.nlm.nih.gov/30361493/
(23) https://pubmed.ncbi.nlm.nih.gov/27424995/
(24) https://pubmed.ncbi.nlm.nih.gov/17487930/
(25) https://www.mdpi.com/1420-3049/24/11/2046/htm
(26) https://www.sciencedirect.com/science/article/pii/B9780702055140000300
(27) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134985/
(28) https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-9-35#Sec1
(29) https://www.health.harvard.edu/press_releases/benefit_of_probiotics_should_you_take_a_daily_dose_of_bacteria
(30) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465228/
(31) https://www.bio-kult.com/userfiles/file/natalie_lamb_uti_article_lowres_mar12.pdf

 

Comfort-U® 30 caps veg (DRcaps)

(22) https://pubmed.ncbi.nlm.nih.gov/30361493/
(23) https://pubmed.ncbi.nlm.nih.gov/27424995/
(24) https://pubmed.ncbi.nlm.nih.gov/17487930/
(25) https://www.mdpi.com/1420-3049/24/11/2046/htm
(26) https://www.sciencedirect.com/science/article/pii/B9780702055140000300
(27) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134985/
(28) https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-9-35#Sec1
(29) https://www.health.harvard.edu/press_releases/benefit_of_probiotics_should_you_take_a_daily_dose_of_bacteria
(30) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465228/
(31) https://pubmed.ncbi.nlm.nih.gov/30361493/

 

Comfort-U® 10 plicuri

(22) https://pubmed.ncbi.nlm.nih.gov/30361493/
(23) https://pubmed.ncbi.nlm.nih.gov/27424995/
(24) https://pubmed.ncbi.nlm.nih.gov/17487930/
(25) https://www.mdpi.com/1420-3049/24/11/2046/htm
(26) https://www.sciencedirect.com/science/article/pii/B9780702055140000300
(27) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134985/
(28) https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-9-35#Sec1
(29) https://www.health.harvard.edu/press_releases/benefit_of_probiotics_should_you_take_a_daily_dose_of_bacteria
(30) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465228/
(31) https://www.bio-kult.com/userfiles/file/natalie_lamb_uti_article_lowres_mar12.pdf

 

Sistemul Osteoarticular

 

Boswellia 450 mg

(5) M. Z. Siddiqui; Boswellia Serrata, A Potential Antiinflammatory Agent: An Overview; Indian J Pharm Sci. 2011 May-Jun; 73(3): 255–261.
(6) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Nov 11, 2014; Last Updated: Sep 30, 2018; Boswellia serrata; https://examine.com/supplements/boswellia-serrata/
(7) FarahIram; Shah AlamKhan; AsifHusain; Phytochemistry and potential therapeutic actions of Boswellic acids: A mini-review; Asian Pacific Journal of Tropical Biomedicine; Volume 7, Issue 6, June 2017, Pages 513-523.

 

Build-Your-Joints 30 caps veg

(8) https://www.capsugel.com/consumer-health-nutrition-products/uc-ll
(9) Lugo JP, et al. Nutr J. 2016;15:14.
(10) Bagi CM, et al. Osteoarthritis Cartilage. 2017;25:2080.
(11) Bagchi D, Misner B, Bagchi M, et al. Effects of orally administered undenatured type II collagen against arthritic inflammatory diseases: a mechanistic exploration. Int J Clin Pharmacol Res. 2002;22(3-4):101-10
(12) Lugo JP, et al. J Int Soc Sports Nutr. 2013;10:48.
(13) Bagi CM, et al. Osteoarthritis Cartilage. 2017;25:2080.
(14) Crowley et al. Int J Med Sci. 2009;6(6):312-21.
(15) https://pubmed.ncbi.nlm.nih.gov/25997859/
(16) https://www.nccih.nih.gov/health/turmeric
(17) https://orthoinfo.aaos.org/en/staying-healthy/calcium-nutrition-and-bone-health/

 

Build-Your-Joints 30 de plicuri

(8) https://www.capsugel.com/consumer-health-nutrition-products/uc-ll
(9) Lugo JP, et al. Nutr J. 2016;15:14.
(10) Bagi CM, et al. Osteoarthritis Cartilage. 2017;25:2080.
(11) Bagchi D, Misner B, Bagchi M, et al. Effects of orally administered undenatured type II collagen against arthritic inflammatory diseases: a mechanistic exploration. Int J Clin Pharmacol Res. 2002;22(3-4):101-10
(12) Lugo JP, et al. J Int Soc Sports Nutr. 2013;10:48.
(13) Bagi CM, et al. Osteoarthritis Cartilage. 2017;25:2080.
(14) Crowley et al. Int J Med Sci. 2009;6(6):312-21.
(15) https://pubmed.ncbi.nlm.nih.gov/25997859/
(16) https://www.nccih.nih.gov/health/turmeric
(17) https://orthoinfo.aaos.org/en/staying-healthy/calcium-nutrition-and-bone-health/
(18) Yatish et al. Evaluation of clinical efficacy of undenatured type II collagen in the treatment of osteoarthritis of knee. A randomized controlled study. Int J Orthopaedics Sci. 2020; 6(2): 497–50

 

Cat's Claw 485 mg

(19) review with reference to osteoporosis", International Journal of Pharmaceutical Science and Health Care, Issue 4, Vol 1. February 2014.
(20) Rajani Chauhan, Vinod Singh et. Al., "CAT'S CLAW: A MIRACLE HERB FROM THE RAIN FOREST OF PERU", Indian Journal of Drugs, 2015, 3(4), 96-101
(21) Goldina Ikezuagu Erowele,  Abolanle O. Kalejaiye, "Pharmacology and therapeutic uses of cat’s claw", American Journal of Health-System Pharmacy, Volume 66, Issue 11, 1 June 2009, Pages 992–995, https://doi.org/10.2146/ajhp080443

 

Hydraplenish® Plus MSM

(22) Stephen R Schwartz and Joosang Park; Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs; Clinical Interventions in Aging; 2012; 7: 267–273.
(23) Alexander G. Schauss, Jerome Stenehjem, Joosang Park, John R. Endres, and Amy Clewell; Effect of the Novel Low Molecular Weight Hydrolyzed Chicken Sternal Cartilage Extract, BioCell Collagen, on Improving Osteoarthritis-Related Symptoms: A Randomized, Double-Blind, Placebo-Controlled Trial; Journal of Agricultural and Food Chemistry; 2012, 60 (16), pp 4096–4101.
** https://www.optimsm.com/
* https://www.biocelltechnology.com/

 

MSM 750 mg

(24) P. K. Gupta, MD (Ayu), S. M. S. Samarakoon, H. M. Chandola, and B. Ravishankar; Clinical evaluation of Boswellia serrata (Shallaki) resin in the management of Sandhivata (osteoarthritis); An International Quarterly of Research in Ayurveda; 2011 Oct-Dec; 32(4): 478–482.
(25) Research analysis lead by Kamal Patel; All content reviewed by Examine.com Team; Published: Jul 19, 2013; Last Updated: Oct 31, 2018; Methylsulfonylmethane; https://examine.com/supplements/methylsulfonylmethane/#ref47.
(26) Have a “Good Hair Day"; 2009 Huntington College of Health Sciences Literature Education Series On Dietary Supplements; Gene Bruno, MS, MHS.
(27) Srinivasan Shanmugam; Rengarajan Baskaran; Santhoshkumar Nagayya-Sriraman; Chul-Soon Yong; Han-Gon Choi; Jong-Soo Woo; The Effect of Methylsulfonylmethane on Hair Growth Promotion of Magnesium Ascorbyl Phosphate for the Treatment of Alopecia; Biomolecules and Therapeutics 17(3):241-248 · July 2009.
** https://www.optimsm.com/

 

MSM ibuActin®

(31) Andrea H. Zengion ND, MSAOM, Eric Yarnell ND, “ Herbal and Nutritional Supplements for Painful Conditions”, Pain Procedures in Clinical Practice (Third Edition), 2011
(32) Mohd Shara and Sidney J. Stohs, “ Efficacy and Safety of White Willow Bark (Salix alba) Extracts”, PHYTOTHERAPY RESEARCH Phytother. Res. 29: 1112–1116 (2015)
(33) Caroline Ospelt, “ Synovial fibroblasts in 2017”, RMD Open. 2017; 3(2): e000471.
(34) Sander Hougee 1, Joyce Faber, Annemarie Sanders et. Al., “ Selective Inhibition of COX-2 by a Standardized CO2 Extract of Humulus Lupulus in Vitro and Its Activity in a Mouse Model of Zymosan-Induced Arthritis”, Planta Med 2006 Feb;72(3):228-33. doi: 10.1055/s-2005-916212.
(35) Matthew Butawan, Rodney L. Benjamin and Richard J. Bloomer, ‘’ Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement”, Nutrients. 2017 Mar; 9(3): 290.
(36) Amy J. Hall a,*, John G. Babish, Gary K. Darland et. Al., “ Safety, efficacy and anti-inflammatory activity of rho iso-alpha-acids from hops”, Phytochemistry 69 (2008) 1534–1547.
(37) Rajendra Pavan, Sapna Jain, Shraddha and Ajay Kumar, “ Properties and Therapeutic Application of Bromelain: A Review”, Biotechnol Res Int. 2012; 2012: 976203.
** https://www.optimsm.com/

 

MSM Advanced

(28) Alternative Medicine Review, Volume 4, Number 3, 1999; Glucosamine Sulfate.
(29) Cécile Bascoul-Colombo, Iveta Garaiova, Sue F. Plummer, John L. Harwood, Bruce Caterson, Clare E Hughes; Glucosamine Hydrochloride but Not Chondroitin Sulfate Prevents Cartilage Degradation and Inflammation Induced by Interleukin-1α in Bovine Cartilage Explants; First Published September 7, 2015.
(30) J. R. E. Fraser T. C. Laurent U. B. G. Laurent; Hyaluronan: its nature, distribution, functions and turnover; Journal of Internal Medicine; First published: 31 October 2003.

 

Glucosamine Chondroitin Hyaluronic Acid

(39) Jörg Jerosch; Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids; International Journal of Rheumatology; 2011; 2011: 969012.
(40) https://www.ncbi.nlm.nih.gov/books/NBK558930/.
(41) Shavlovskaya O.A., Zolotovskaya I.A., Prokofyeva Yu.S. Anti-inflammatory and anti-aging effects of chondroitin sulfate. Neurology, Neuropsychiatry, Psychosomatics. 2020;12(5):111-116. (In Russ.) https://doi.org/10.14412/2074-2711-2020-5-111-116 .
(42) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643354/.
(43) https://cartilage.org/patient/about-cartilage/can-i-be-treated-without-surgery/hyaluronic- acidviscosupplementation/.
(44) Bissett DL. Glucosamine: an ingredient with skin and other benefits. J Cosmet Dermatol. 2006 Dec;5(4):309-15. doi: 10.1111/j.1473-2165.2006.00277.x. PMID: 17716251.

 

Joint Movement Glucosamine

(35) Matthew Butawan, Rodney L. Benjamin and Richard J. Bloomer, ‘’ Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement”, Nutrients. 2017 Mar; 9(3): 290.
(38) Jörg Jerosch; Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids; International Journal of Rheumatology; 2011; 2011: 969012.

 

Imunitate

 

Andrographis SE

(1) Md. Sanower Hossain, Zannat Urbi et. Al., "Andrographis paniculata (Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology", ScientificWorldJournal. 2014; 2014: 274905

 

Astragalus 470 mg

(2) Steven Sinclair, N.D. L.Ac., " Chinese Herbs: A Clinical Review of Astragalus, Ligusticum, and Schizandrae", Alternative Medicine Review ◆ Volume 3, Number 5, pg. 338-341◆ 1998
(3) Lesley Braun, Marc Cohen, " Herb& Natural Supplements- An evidence-based guide", 3RD EDITION, Astragalus213-218 pg. 509-524.
(4) Zhenzhen Guo, Yanmei Lou et. Al., "A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine", International Journal of Molecular Sciences, March 2019.
(5) C. M. Yang, Q. J. Han et. Al., '' Astragalus and Ginseng Polysaccharides Improve Developmental, Intestinal Morphological, and Immune Functional Characters of Weaned Piglets'', Front Physiol. 2019; 10: 418.

 

Colostrum Prime Life

(6) Meena L Godhia and Neesah Patel, "Colostrum - its Composition, Benefits as a Nutraceutical - A Review.", ISSN: 2347-467X, Online ISSN: 2322–0007

 

Echinacea

(7) Joanne Barnes, Linda A. Anderson, Simon Gibbons and J. David Phillipson, "Echinacea species (Echinacea angustifolia (DC.) Hell.,Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.)Moench): a review of their chemistry, pharmacology and clinical properties", Journal of Pharmacy and Pharmacology, JPP 2005, 57: 929–954.
(8) Annahita Rezaie, Ali Fazlara et. Al., "Effects of Echinacea purpurea on Hepatic and Renal Toxicity Induced by Diethylnitrosamine in Rats", Jundishapur J Nat Pharm Prod. 2013;8(2)

 

C-Your-Immunity®

(43) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/
(44) https://www.nature.com/scitable/topicpage/the-mystery-of-vitamin-c-14167861/
(45) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707683/
(46) https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
(47) https://aacijournal.biomedcentral.com/articles/10.1186/1710-1492-10-58#Abs1
(48) https://www.hindawi.com/journals/omcl/2019/7286737/#abstract
(49) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273625/
(50) http://www.bslonline.org/journal/download_pdf.php?spage=83&volume=16&number=2
(51) https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100315&lng=pt&nrm=iso
(52) https://www.hindawi.com/journals/btri/2012/976203/

 

Fo-Ti 610 mg

(9) Yue Liu, Qi Wang, Jianbo Yang, Xiaohan Guo, Wenxi Liu, Shuangcheng Ma, and Shaoping Li4, Polygonum multiflorum Thunb.: A Review on Chemical Analysis, Processing Mechanism, Quality Evaluation, and Hepatotoxicity; Frontiers in Pharmacology. 2018; 9: 364.
(10) H. J. Yang, M. J. Kim, H. J. Kang, H. Y. Lee, Y. M. Park, Y. H. Lee1, Y. G. Kang1, G. P. Hwa1, Y. S. Kang, Y. M. Jung, N. K. Lee and K-H. Park; Immunomodulating Properties of Polygonum multiflorum Extracts on Cyclophosphamide-induced Immunosuppression Model; Indian Journal of Pharmacologycal Science; 2018;80(4):749-755.
(11) Guy-Armel Bounda and YU Feng; Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds; Pharmacognosy Research. 2015 Jul-Sep; 7(3): 225–236.
(12) Botanical Safety Handbook, second edition; American Herbal Products Association’s; 2013; Edited by: Zoe Gardner, Michael McGuffin; Expert Advisory Council: Roy Upton, Soaring Bear, David Winston, Daniel Gagnon, Aviva Jill Romm, Tieraona Low Dog, Mary Hardy, Lyle Craker; pg. 730-732.
(13) Nguyen Dinh Thang, Pham Ngoc Diep, Pham Thi Huong Lien, and Le Thi Lien; Polygonum multiflorum root extract as a potential candidate for treatment of early graying hair; Journal of Advanced Pharmaceutical Technology Research; 2017 Jan-Mar; 8(1): 8–13; doi: 10.4103/2231-4040.197332.

 

Garlic (Usturoi) 480 mg

(37) Joseph E.Pizzorno, Michael,T.Murray, HerbJoiner-Bey, Varicose Veins, The Clinician's Handbook of Natural Medicine (THIRD EDITION).
(38) https://www.ema.europa.eu/en/documents/herbal-report/draft-assessment-report-allium-sativum-l-bulbus_en.pdf
(39) Ademiluyi AO, Oboh G, Owoloye TR, Agbebi OJ. Modulatory effects of dietary inclusion of garlic (Allium sativum) on gentamycin-induced hepatotoxicity and oxidative stress in rats. Asian Pac J Trop Biomed. 2013;3(6):470–475. doi:10.1016/S2221-1691(13)60098-2
(40) Qamar A, Usmani A, Waqar H, Siddiqui A, Kumar H. Ameliorating effect of Allium Sativum on high-fat diet induced fatty liver in albino rats. Pak J Med Sci. 2016;32(2):403–407. doi:10.12669/pjms.322.9025
(41) Petrovska BB, Cekovska S. Extracts from the history and medical properties of garlic. Pharmacogn Rev. 2010;4(7):106–110. doi:10.4103/0973-7847.65321
(42) Bayan L, Koulivand PH, Gorji A. Garlic: a review of potential therapeutic effects. Avicenna J Phytomed. 2014;4(1):1–14.

 

Goldenseal 570 mg

(14) Lesley Braun, Marc Cohen; Herbs and Natural Supplements. An evidence-based guide, 3rd Edition; Goldenseal; pg. 557-565.
(15) Aviv aRomm; Bevin Clare; Lisa Alschuler; Christopher Hobbs; Roy Upton; Botanical Medicine for Women's Health; 2010, Pages 256-289; CHAPTER 8 - Vaginal Infections and Sexually Transmitted Diseases.
(16) Research analysis lead by Kamal Patel; All content reviewed by Examine.com Team. Published: Mar 23, 2014; Last Updated: Dec 31, 2018; Berberine; Examine.com; https://examine.com/supplements/berberine/

 

Grapefruit Seed Extract 250 mg

(17) Sangita Sharma, Tony Sheehy and Laurence Kolonel; Sources of vegetables, fruits, and vitamins A, C and E among five ethnic groups: Results from the Multiethnic Cohort Study; European Journal of Clinic and Nutrition; 2014 Mar; 68(3): 384–391; Published online 2014 Jan 8. doi: 10.1038/ejcn.2013.271.
(18) Vankateswara Rao P; SDVC Kiran; Rohini P and Bhagyasree P; Flavonoid: A Review on Naringenin; Journal of Pharmacognosy and Phytochemistry; pg. 2778-2783; 2017.

 

Immuno C with Zinc and Vitamin D3

(36) Gene Bruno, ˝Vitamin C & Bioflavonoids", ©2002 Huntington College of Health Sciences

 

Immuno-Essentials 15 comp dublu-strat (Bi-layer)

(65)https://mitohacker.pl/wp-content/uploads/2020/03/Vitamins-C-D-and-Zinc-Synergistic-Roles-in-Immune-Function.pdf
(66)https://www.frontiersin.org/articles/10.3389/fphys.2019.00194/full
(67)https://www.hindawi.com/journals/isrn/2013/898125/
(68)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465887/
(69)https://www.sciencedirect.com/science/article/abs/pii/S0531556507002458
(70)https://www.jneurosci.org/content/jneuro/20/23/RC111.full.pdf
(71)https://www.mdpi.com/1420-3049/25/22/5346#cite
(72)https://www.mdpi.com/2072-6643/10/9/1203/htm
(73)https://www.ncbi.nlm.nih.gov/books/NBK557551/

 

Immunity-By-Night®

(55) https://www.ema.europa.eu/en/documents/herbal-summary/valerian-root-hop-strobile-summary-public_en.pdf
(56) Liu, Y., Gu, X.-H., Tang, J., & Liu, K. (2007). Antioxidant Activities of Hops (Humulus Lupulus) and Their Products. Journal of the American Society of Brewing Chemists, 65(2), 116–121. doi:10.1094/asbcj-2007-0211-01
(57) Samir Malhotra, Girish Sawhney and Promila Pandhi, " The Therapeutic Potential of Melatonin: A Review of the Science", MedGenMed. 2004; 6(2): 46.
(58) Carrillo-Vico, A., Lardone, P. J., Alvarez-Sánchez, N., Rodríguez-Rodríguez, A., & Guerrero, J. M. (2013). Melatonin: buffering the immune system. International journal of molecular sciences, 14(4), 8638–8683. https://doi.org/10.3390/ijms14048638
(59) Otocka-Kmiecik A, Król A. The Role of Vitamin C in Two Distinct Physiological States: Physical Activity and Sleep. Nutrients. 2020 Dec 21;12(12):3908. doi: 10.3390/nu12123908. PMID: 33371359; PMCID: PMC7767325.
(60) Name JJ, Souza ACR, Vasconcelos AR, Prado PS, Pereira CPM. Zinc, Vitamin D and Vitamin C: Perspectives for COVID-19 With a Focus on Physical Tissue Barrier Integrity. Front Nutr. 2020 Dec 7;7:606398.
(61) Romano F, Muscogiuri G, Di Benedetto E, Zhukouskaya VV, Barrea L, Savastano S, Colao A, Di Somma C. Vitamin D and Sleep Regulation: Is there a Role for Vitamin D? Curr Pharm Des. 2020;26(21):2492-2496.
(62) Wrzosek M, Łukaszkiewicz J, Wrzosek M, Jakubczyk A, Matsumoto H, Piątkiewicz P, Radziwoń-Zaleska M, Wojnar M, Nowicka G. Vitamin D and the central nervous system. Pharmacol Rep. 2013;65(2):271-8.
(63) Ananda S Prasad, Zinc in Human Health: Effect of Zinc on Immune Cells, Mol Med. 2008 May-Jun; 14(5-6): 353–357.
(64) https://www.psychologytoday.com/ie/articles/201807/zzzz-zinc

 

L-Lysine 500 mg

(19) Cody J. Hall, Tatiana P. Soares de Costa; Lysine: biosynthesis, catabolism and roles; Wiki Journal of Science, 2018

 

Lactoferrin 250 mg

(20) L. Adlerova, A. Bartoskova, M. Faldyna; Lactoferrin: a review; Veterinarni Medicina, 53, 2008 (9): 457–468.
(21) Paulina Markowiak and Katarzyna Śliżewska; Effects of Probiotics, Prebiotics, and Synbiotics on Human Health; Nutrients. 2017 Sep; 9(9): 1021; Published online 2017 Sep 15. doi: 10.3390/nu9091021.

 

Monolaurin 500 mg

(53) Lisa A. Barker, DC, Barclay W. Bakkum, “ The Clinical Use of Monolaurin as a Dietary Supplement: A Review of the Literature”, Journal List, J Chiropr Med. 2019 Dec; 18(4): 305–310.
(54) https://info.dralexrinehart.com/articles/monolaurin-a-secret-compound-from-coconut-oil-with-powerful-immune-benefits

 

Myco Defense®

(7) Joanne Barnes, Linda A. Anderson, Simon Gibbons and J. David Phillipson, "Echinacea species (Echinacea angustifolia (DC.) Hell.,Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.)Moench): a review of their chemistry, pharmacology and clinical properties", Journal of Pharmacy and Pharmacology, JPP 2005, 57: 929–954.
(22) Komsit Wisitrassameewong, Samantha C. Karunarathna, Naritsada Thongklang, Ruilin Zhao, Philippe Callac, Serge Moukha, Cyril Férandon, Ekachai Chukeatirote, and Kevin D. Hyde; Agaricus subrufescens: A review; Saudi Journal of Biological Science; 2012 Apr; 19(2): 131–146.
(23) Sensuke Konno; Synergistic potentiation of D-fraction with vitamin C as possible alternative approach for cancer therapy; International Journal of General Medicine; 2009; 2: 91–108.

 

Olive Leaf 20% SE(24) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Publishe+B388:B396d: Nov 16, 2014; Last Updated: Jun 14, 2018; Olive leaf; Examine.com; https://examine.com/supplements/olive-leaf-extract/#neurology_neuroprotection

 

Shilajit Fulvic Acid Complex 250 mg

(25) https://natreoninc.com/(26) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Jun 24, 2014; Last Updated: Oct 2, 2018; Shilajit; Examine.com; https://examine.com/supplements/shilajit/

 

SystemWell® Ultimate Immunity™

(27) Carr AC, Maggini S; Vitamin C and Immune Function; Nutrients. 2017 Nov 3;9(11). pii: E1211. doi:10.3390/nu9111211.
(28) Cynthia Aranow, MD, Investigator; Vitamin D and the Immune System; Journal of Investigative Medicine; 2011 Aug; 59(6): 881–886; doi: 10.231/JIM.0b013e31821b8755.
(29) Rodrigo Arreola, Saray Quintero-Fabián, Rocío Ivette López-Roa, Enrique Octavio Flores-Gutiérrez, Juan Pablo Reyes-Grajeda, Lucrecia Carrera-Quintanar, and Daniel Ortuño-Sahagún; Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds; Journal of Immunology Research; 2015; 2015: 401630; Published online 2015 Apr 19.
(30) Rostami H, Seidavi A, Dadashbeiki M, Asadpour Y, Simões J, Shah AA, Laudadio V, Losacco C, Perillo A, Tufarelli V; Supplementing dietary rosemary (Rosmarinus officinalis L.) powder and vitamin E in broiler chickens: evaluation of humoral immune response, lymphoid organs, and blood proteins; Environmental Science and Pollution Research Internationa; 2018 Mar;25(9):8836-8842. doi: 10.1007/s11356-018-1209-x. Epub 2018 Jan 12.
(31) Eun-Hwa Sohn, Seon-A Jang, Haemi Joo, Sulkyoung Park, Se-Chan Kang, Chul-Hoon Lee and Sun-Young; Anti-allergic and anti-inflammatory effects of butanol extract from Arctium Lappa L; Clinical and Molecular Allergy20119:4.
(32) Sajad Ahmad Wani; Pradyuman Kumar; Fenugreek: A review on its nutraceutical properties and utilization in various food products; Journal of the Saudi Society of Agricultural Sciences; Volume 17, Issue 2, April 2018, Pages 97-106.
(33) Karen Denzler, Jessica Moore, Heather Harrington, Kira Morrill, Trung Huynh, Bertram Jacobs, Robert Waters, and Jeffrey Langland; Characterization of the Physiological Response following In Vivo Administration of Astragalus membranaceus; Evidence Based Complementary and Alternative Medicine; 2016; 2016: 6861078; Published online 2016 Apr 12. doi: 10.1155/2016/6861078.
(34) Paulina Markowiak and Katarzyna Śliżewska; Effects of Probiotics, Prebiotics, and Synbiotics on Human Health; Nutrients. 2017 Sep; 9(9): 1021; Published online 2017 Sep 15. doi: 10.3390/nu9091021.

 

Thymus Plus Caps™

(35) GR.Nireesha; L.Divya; C.Sowmya; N.Venkateshan; M. Niranjan Babu and V.Lavakumar; Lyophilization/Freeze Drying - An Review; INTERNATIONAL JOURNAL OF NOVEL TRENDS IN PHARMACEUTICAL SCIENCES; Article history: Received 30 Sep 2013; Revised 7 Oct 2013; Accepted 16 Oct 2013; Available online 30 Oct 2013.

 

Sistemul Cardiovascular - Cardioprotectoare

 

BP Defense™

(1) S. Iravani and B. Zolfaghari; Pharmaceutical and nutraceutical effects of Pinus pinaster bark extract; Res Pharm Sci. 2011 Jan-Jun; 6(1): 1–11.
(2) Jie Wang, Xingjiang Xiong, and Bo Feng*, “ Effect of Crataegus Usage in Cardiovascular Disease Prevention: An Evidence-Based Approach”, Evid Based Complement Alternat Med. 2013; 2013: 149363.
(3) Aswin Rafif Khairullah, Tridiganita Intan Solikhah et. Al., “ Review on the Pharmacological and Health Aspects of Apium Graveolens or Celery: An Update”, Sys Rev Pharm 2021;12(1):606-612, A multifaceted review journal in the field of pharmacy
(4) YulanZhao, ChuanlianXu, “ Structure and Function of Angiotensin Converting Enzyme and Its Inhibitors”, Chinese Journal of Biotechnology, Volume 24, Issue 2, February 2008, Pages 171-176.

 

Circulation Blend SP-11B

(5) Singh, Vinay & Singh, Dinesh. (2008). Pharmacological Effects of Garlic (Allium sativum L.). Annual Review of Biomedical Sciences. 10. 10.5016/1806-8774.2008.v10p6.
(6) https://www.webmd.com/vitamins/ai/ingredientmono-320/butchers-broom

 

Coenzyme Q10

(7)https://www.mayoclinic.org/drugs-supplements-coenzyme-q10/art-20362602
(8)https://www.indena.com/product/ubiqsome/
(9)https://www.indena.com/indena_files/2022/03/ubiqsome_ss_int.pdf
(10)https://www.sciencedirect.com/science/article/abs/pii/S1567724907000591?via%3Dihub
(11)https://www.frontiersin.org/articles/10.3389/fphar.2022.883251/full
(12)Forsmark-Andrée P, Ernster L. Evidence for a protective effect of endogenous Ubiquinol against oxidative damage to mitochondrial.
(13)Dai, S.; Tian, Z.; Zhao, D.; Liang, Y.; Liu, M.; Liu, Z.; Hou, S.; Yang, Y. Effects of Coenzyme Q10 Supplementation on Biomarkers of Oxidative Stress in Adults: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials. Antioxidants 2022, 11, 1360. https://doi.org/10.3390/antiox11071360
(14)https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/biof.1839
(15)http://diposit.ub.edu/dspace/handle/2445/172555
(16)https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2010.1793
(17)Sarmiento A, Diaz-Castro J, Pulido-Moran M, Moreno-Fernandez J, Kajarabille N, Chirosa I, Guisado IM, Javier Chirosa L, Guisado.
(18)Belardinelli, RM et al. American Heart Association Supplement to Circulation. October 28, 2003. Vol. 108 (17), pg. 739.
(19)https://www.fortunejournals.com/articles/efficient-muscle-distribution-reflects-the-positive-influence-of-coenzyme-q10-phytosome-in-healthy-aging-athletes-after-stressing-.html
(20)https://article.imrpress.com/bri/Landmark/articles/pdf/Landmark4231.pdf
(21) https://www.ahajournals.org/doi/10.1161/JAHA.118.009835
(22)https://www.mayoclinic.org/drugs-supplements-coenzyme-q10/art-20362602
(23)https://rjp.com.ro/articles/2008.2/RJP_2008_2_Art-15.pdf
(24) https://www.indena.com/indena_files/2020/01/wp_phytosome_int.pdf

 

Nattokinase 100 mg

(25) Hongjie Chen, Eileen M McGowan, Nina Ren, “ Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases”, Biomark Insights. 2018; 13:1177271918785130.

 

PQQ 20 mg

(26) Akagawa M, Nakano M, Ikemoto K; Recent progress in studies on the health benefits of pyrroloquinoline quinone; Bioscience, Biotechnology, Biochemistry, 2016;80(1):13-22. doi: 10.1080/09168451.2015.1062715. Epub 2015 Jul 13.
(27) Kei Ohwada, Hironobu Takeda, Makiko Yamazaki, Hirosi Isogai, Masahiko Nakano, Masao Shimomura, Koji Fukui, Shiro Urano; Pyrroloquinoline Quinone (PQQ) Prevents Cognitive Deficit Caused by Oxidative Stress in Rats; Journal of Clinical Biochemistry and Nutrition; 008 Jan; 42(1): 29–34; Published online 2007 Dec 28. doi: 10.3164/jcbn.2008005.
(28) Rong Tao, Joel S. Karliner, Ursula Simonis, Jie Zheng, Jianqing Zhang, Norman Honbo, Conrad C. Alano; Pyrroloquinoline Quinone Preserves Mitochondrial Function and Prevents Oxidative Injury in Adult Rat Cardiac Myocytes; Biochem Biophys Res Commun. Author manuscript; available in PMC 2010 Mar 23; Published in final edited form as; Biochem Biophys Res Commun. 2007 Nov 16; 363(2): 257–262.; Published online 2007 Aug 14. doi: 10.1016/j.bbrc.2007.08.041
(29) Mitsugu Akagawa,Masahiko Nakano &Kazuto Ikemoto; Recent progress in studies on the health benefits of pyrroloquinoline quinone; Journal of Bioscience, Biotechnology, and Biochemistry; Volume 80, 2016 - Issue 1.
(30) Marjan Nassiri-Asl1 and Hossein Hosseinzadeh; REVIEW; Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Update; PHYTOTHERAPY RESEARCH; Phytother. Res. 30: 1392–1403 (2016); Published online 16 May 2016 in Wiley Online Library; (wileyonlinelibrary.com) DOI: 10.1002/ptr.5644.

 

Pure Omega-3

(31)https://solutexcorp.com/technology/platforms/#flutex
(32) Lawson LD, Hughes BG., 1988. Absorption of eicosapentaenoic acid and docosahexaenoic acid from fish oil triacylycerols or fish oil ethyl esters co-ingested with a high-fat meal. Biochem Biophys ResCommun. Oct 31; 156(2):960-3
(33) https://goedomega3.com/storage/app/media/scientific-monographs/Cardiovascular%20Health%20Monograph.pdf
(34) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834330/
(35) https://goedomega3.com/storage/app/media/scientific-monographs/Joint%20Health%20Monograph.pdf
(36) https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/
(37) https://lipidworld.biomedcentral.com/articles/10.1186/s12944-020-01295-7
(38) Prottey, C.; Hartop, P.J.; Press, M. Correction of the cutaneous manifestations of essential fatty acid deficiency in man by application of sunflower-seed oil to the skin. The Journal of investigative dermatology 1975, 64, 228-234.
(39)https://www.sciencedirect.com/science/article/pii/S1323893014000100#:~:text=Omega%2D3%20fatty%20acids%2C%20docosahexaenoic,diseases%20including%20asthma%20and%20allergies.
(40) https://solutexcorp.com/technology/platforms/#flutex
(41) https://goedomega3.com/intake-recommendations
(42) Goldberg RJ, Katz J. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain. Pain. 2007 May;129(1-2):210-23. doi: 10.1016/j.pain.2007.01.020. Epub 2007 Mar 1. PMID: 17335973.
(43) Huang, T. H., Wang, P. W., Yang, S. C., Chou, W. L., & Fang, J. Y. (2018). Cosmetic and Therapeutic Applications of Fish Oil's Fatty Acids on the Skin. Marine drugs, 16(8), 256. https://doi.org/10.3390/md16080256
(44) Hibbeln JR. Depression, suicide and deficiencies of omega-3 essential fatty acids in modern diets. World Rev Nutr Diet 2009;99:17-30.
(45) Simopoulos AP. Evolutionary Aspects of Diet: The Omega-6/Omega-3 Ratio and the Brain. Mol Neurobiol 2011;44:203-215
(46) Pottala JV, Yaffe K, Robinson JG, Espeland MA, Wallace R, Harris WS (2014). Higher RBC EPA + DHA corresponds with larger total brain and hippocampal volumes: WHIMS-MRI Study. Neurology 82:435-442
(47) https://www.sciencedirect.com/science/article/pii/S1323893014000100
(48) https://www.sciencedirect.com/science/article/pii/S1756464615000262

 

Pycnogenol® 50 mg

(49) S. Iravani and B. Zolfaghari; Pharmaceutical and nutraceutical effects of Pinus pinaster bark extract; Res Pharm Sci. 2011 Jan-Jun; 6(1): 1–11.
(50) Cindy K. Angerhofer, Daniel Maes, Paolo U. Giacomoni; Chapter 10 - The Use of Natural Compounds and Botanicals in the Development of Anti-Aging Skin Care Products; Skin Aging Handbook; An Integrated Approach to Biochemistry and Product Development; Personal Care & Cosmetic Technology; 2009, Pages 205-263.

 

QH-absorb® (Co-Q10 200 mg)

(51) Studiu clinic efectuat de Jarrow Formulas®: Q-absorb® în insuficiența cardiacă cronică “Coenzima Q10 potențează efectele antrenamentului asupra factorului endotelial vasodilatator al arterei brahiale în insuficiența cardiacă cronică"; Belardinelli, RM et al. American Heart Association Supplement to Circulation. October 28, 2003. Vol. 108 (17), pg. 739.
(52) Beamer WM and Deamer DW. Energy from Chemical Bonds: The aerobic mode. In: The World of the Cell, 2nd Ed., The Benjamin Cummin.
(53) Forsmark-Andrée P, Ernster L. Evidence for a protective effect of endogenous Ubiquinol against oxidative damage to mitochondrial.
(54) Sarmiento A, Diaz-Castro J, Pulido-Moran M, Moreno-Fernandez J, Kajarabille N, Chirosa I, Guisado IM, Javier Chirosa L, Guisado.
(55) Shoko D, Fujii K, Kurihara T. The effect of the reduced form of coenzyme Q10 (Ubiquinol, Kaneka QH™ ) on QOL improvement in the elderly.
(56) Studiu clinic ce demonstrează biodisponibilitatea superioară a produsului QH-absorb®, iunie 2009, Universitatea din Ancona, Italia.
(57) https://www.kanekanutrients.com/

 

Resveratrol 100 mg

(58) Adele Chimento; Francesca De Amicis, Rosa Sirianni; Maria Stefania Sinicropi; Francesco Puoci; Ivan Casaburi; Carmela Saturnino and Vincenzo Pezzi; Progress to Improve Oral Bioavailability and Beneficial Effects of Resveratrol; International Journal of Molecular Science; Published: 19 March 2019.
(59) Hui-Yun Tsai; Chi-TangHo; Yu-KuoChen; Biological actions and molecular effects of resveratrol, pterostilbene, and 3′-hydroxypterostilbene; Journal of Food and Drug Analysis; Volume 25, Issue 1, January 2017, Pages 134-147;
(60) Bahare Salehi, Abhay Prakash Mishra, Manisha Nigam, Bilge Sener, Mehtap Kilic, Mehdi Sharifi-Rad, Patrick Valere Tsouh Fokou, Natália Martins, and Javad Sharifi-Rad; Resveratrol: A Double-Edged Sword in Health Benefits; Biomedicines. 2018 Sep; 6(3): 91; Published online 2018 Sep 9. doi: 10.3390/biomedicines6030091.

 

Total Cleanse™ Lymph

(61) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Jul 20, 2013; Last Updated: Jun 14, 2018; Horse Chestnut; Examine.com; https://examine.com/supplements/horse-chestnut/
(62) Ali Esmail Al-Snafi; CHEMICAL CONSTITUENTS AND MEDICAL IMPORTANCE OF GALIUM APARINE - A REVIEW; INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES; ISSN: 2349-7750.
(63) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Aug 20, 2013; Last Updated: Mar 21, 2019; Centella asiatica (Gotu Kola); Examine.com; https://examine.com/supplements/centella-asiatica/

 

trans - Pterostilbene 50 mg

(59) Hui-Yun Tsai; Chi-TangHo; Yu-KuoChen; Biological actions and molecular effects of resveratrol, pterostilbene, and 3′-hydroxypterostilbene; Journal of Food and Drug Analysis; Volume 25, Issue 1, January 2017, Pages 134-147;

 

Vein Defense™

(64) Amita Pandey, Shalini Tripathi, Concept of standardization, extraction and pre phytochemical screening strategies for herbal drug, Journal of Pharmacognosy and Phytochemistry 2014; 2 (5): 115-119
(65) https://www.bioperine.com/index.php/mechanismsofactions
(66) Redman DA, Ruscus aculeatus (butcher's broom) as a potential treatment for orthostatic hypotension, with a case report, J Altern Complement Med. 2000 Dec;6(6):539-49
(67) Ya-Lin Huang, Jun-Ping Kou, Li Ma, Jia-Xi Song, and Bo-Yang Y, Possible Mechanism of the Anti-inflammatory Activity of Ruscogenin: Role of Intercellular Adhesion Molecule-1 and Nuclear Factor-κB, J Pharmacol Sci 108, 198 – 205 (2008)2
(68) Joseph E.Pizzorno, Michael,T.Murray, HerbJoiner-Bey, Varicose Veins, The Clinician's Handbook of Natural Medicine (THIRD EDITION)

 

Subsegment: Managementul colesterolului

 

Borage Oil 1300 mg

(1) Yang-Yi Fan and Robert S. Chapkin, " Importance of Dietary γ-Linolenic Acid in Human Health and Nutrition", Recent Advances in Nutricional Science, 18 June 1998.
(2) Bunce OR, Abou-El-Ela SH, "Eicosanoid synthesis and ornithine decarboxylase activity in mammary tumors of rats fed varying levels and types of n-3 and/or n-6 fatty acids", Prostaglandins Leukot Essent Fatty Acids1990;41:105-113.
(3) J.M. BOURRE, " ROLES OF UNSATURATED FATTY ACIDS (ESPECIALLY OMEGA-3 FATTYACIDS) IN THE BRAIN AT VARIOUS AGES AND DURING AGEING", The Journal of Nutrition, Health & Aging©, Volume 8, Number 3, 2004.

 

Cholesterol Blend™

(4) Lesley Braun, Marc Cohen, " Herb& Natural Supplements- An evidence-based guide", 3RD EDITION, Psyllium, pages: 767-771.
(5) Reginald H. Walter, ˝ The Chemistry and Technology of Pectin˝, Food Science and Technology, A Series of Monographs, 1991.
(6) Lesley Braun, Marc Cohen, " Herb& Natural Supplements- An evidence-based guide", 3RD EDITION, Hawthorn, pages: 591-598.
(7) Souravh Bais, Naresh Singh Gill et.al., ˝ A Phytopharmacological Review on a Medicinal Plant: Juniperus communis˝, Int Sch Res Notices. 2014; 2014: 634723.

 

Cholesterol Control RedYeastRice CoQ10

(8) Juan Garrido-Maraver,Mario D. Cordero et. Al., ˝ Coenzyme Q10 Therapy˝, Mol Syndromol. 2014 Jul; 5(3-4): 187–197.
(9) Daniela Casagrande, Paulo H. Waib, Alceu Afonso Jordão Júnior, ˝ Mechanisms of action and effects of the administration of Coenzyme Q10 on metabolic syndrome˝, Journal of Nutrition & Intermediary Metabolism, Volume 13, September 2018, Pages 26-32.
(10) Özlem ERDOĞRUL, Sebile AZIRAK2, ˝ REVIEW of THE STUDIES on THE RED YEAST RICE (Monascus purpureus)˝, Turkish Electronic Journal of Biotechnology Vol 2, p:37-49, 2004 © Biotechnology Association
(11) G. F. Watts, D. A. Playford et. Al., ˝ Coenzyme Q10 improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus˝ Diabetologia(2002)45: 420-426.

 

Citrus Bergamot 500 mg

(12) Mirielle C. Nauman and Jeremy J. Johnson, ˝ Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers˝, Integr Food Nutr Metab. 2019 Mar; 6(2): 10.15761/IFNM.1000249.
(13) Ted Wissink, Craig Schneider and S. Tyler O’Sullivan, ˝ Bergamot Shows Potential as an Alternative to Statins for Hyperlipidemia˝, July 1, 2017

 

Krill Oil

(17) https://www.superbakrill.com/krill-oil/what-is-krill-oil
(18) https://www.superbakrill.com/krill-oil/sustainability
(19) https://www.superbakrill.com/krill-oil/traceability
(20) Casula, M.; Soranna, D.; Catapano, A.L.; Corrao, G. Long-term effect of high dose omega-3 fatty acid supplementation for secondary prevention of cardiovascular outcomes: A meta-analysis of randomized, placebo controlled trials [corrected]. Atheroscler Suppl 2013, 14, 243-251.
(21) Ramprasath, V.R.; Eyal, I.; Zchut, S.; Jones, P.J. Enhanced increase of omega-3 index in healthy individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fish oil. Lipids Health Dis 2013, 12, 178.
(22) Wang, C.; Harris, W.S.; Chung, M.; Lichtenstein, A.H.; Balk, E.M.; Kupelnick, B.; Jordan, H.S.; Lau, J. N-3 fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: A systematic review. Am J Clin Nutr 2006, 84, 5-17.
(23) Wen, Y.T.; Dai, J.H.; Gao, Q. Effects of omega-3 fatty acid on major cardiovascular events and mortality in patients with coronary heart disease: A meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis 2014, 24, 470-475.
(24) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583249/
(25) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049853/
(26) Liu, A.; Ji, J. Omega-3 essential fatty acids therapy for dry eye syndrome: A meta-analysis 60 KRILL OIL CONCENTRATE of randomized controlled studies. Medical science monitor : international medical journal of experimental and clinical research 2014, 20, 1583-1589.
(27) Prottey, C.; Hartop, P.J.; Press, M. Correction of the cutaneous manifestations of essential fatty acid deficiency in man by application of sunflower-seed oil to the skin. The Journal of investigative dermatology 1975, 64, 228-234.
(28) https://www.researchgate.net/publication/270133540_An_open-label_pilot_study_to_assess_the_effectiveness_of_krill_oil_with_added_vitamins_and_phytonutrients_in_the_relief_of_symptoms_of_PMS
(29) Antypa, N.; Van der Does, A.J.; Smelt, A.H.; Rogers, R.D. Omega-3 fatty acids (fish-oil) and depression-related cognition in healthy volunteers. Journal of psychopharmacology 2009, 23, 831-840.
(30) https://www.superbakrill.com/health-benefits-of-krill-oil
(31) Krishnadev, N.; Meleth, A.D.; Chew, E.Y. Nutritional supplements for age-related macular degeneration. Curr Opin Ophthalmol 2010, 21, 184-189.
(32) Haruta, Y.; Kato, K.; Yoshioka, T. Dietary phospholipid concentrate from bovine milk improves epidermal function in hairless mice. Biosci Biotechnol Biochem 2008, 72, 2151-2157.
(33) Jump, D.B.; Thelen, A.; Ren, B.; Mater, M. Multiple mechanisms for polyunsaturated fatty acid regulation of hepatic gene transcription. Prostaglandins Leukot Essent Fatty Acids 1999, 60, 345-349.
(34) Harris, W.S.; Varvel, S.A.; Pottala, J.V.; Warnick, G.R.; McConnell, J.P. Comparative effects of an acute dose of fish oil on omega-3 fatty acid levels in red blood cells versus plasma: Implications for clinical utility. J Clin Lipidol 2013, 7, 433-440.
(35) Nieman, D.C.; Ahle, J.C.; Henson, D.A.; Warren, B.J.; Suttles, J.; Davis, J.M.; Buckley, K.S.; Simandle, S.; Butterworth, D.E.; Fagoaga, O.R., et al. Indomethacin does not alter natural killer cell response to 2.5 h of running. Journal of applied physiology 1995, 79, 748-755.
(36) Burri L, KRILL OIL CONCENTRATE: The phospholipid factor that sets krill oil apart, 2017, 10-33.
(37) Ramprasath, V.R.; Eyal, I.; Zchut, S.; Shafat, I.; Jones, P.J. Supplementation of krill oil with high phospholipid content increases sum of epa and dha in erythrocytes compared with low phospholipid krill oil. Lipids Health Dis 2015, 14, 142.
(38) Camera, E.; Mastrofrancesco, A.; Fabbri, C.; Daubrawa, F.; Picardo, M.; Sies, H.; Stahl, W. Astaxanthin, canthaxanthin and beta-carotene differently affect uva-induced oxidative damage and expression of oxidative stress-responsive enzymes. Experimental dermatology 2009, 18, 222-231.
(39) Guerin, M.; Huntley, M.E.; Olaizola, M. Haematococcus astaxanthin: Applications for human health and nutrition. Trends in biotechnology 2003, 21, 210-216.

 

Lipotropic 1000 Plus™

(14) Sherriff JL, O'Sullivan TA, Properzi C, Oddo JL, Adams LA. Choline, Its Potential Role in Nonalcoholic Fatty Liver Disease, and the Case for Human and Bacterial Genes. Adv Nutr. 2016;7(1):5–13. Published 2016 Jan 7. doi:10.3945/an.114.007955
(15) John T. Brosnan, Margaret E. Brosnan, The Sulfur-Containing Amino Acids: An Overview, The Journal of Nutrition, Volume 136, Issue 6, June 2006, Pages 1636S–1640S, https://doi.org/10.1093/jn/136.6.1636S
(16) https://www.healthline.com/nutrition/vitamin-b6-benefits#section8

 

 

Sistemul Nervos

Subsegment: Memorie, atenție, capacitate de concentrare, efort intellectual

 

Acetyl L-Carnitine 500 mg(1) Giovanna Traina; The neurobiology of acetyl-L-carnitine; [Frontiers in Bioscience, Landmark, 21, 1314-1329, June 1, 2016].
(2) Acetyl-L-carnitine. Monograph"; Alternative Medicine Review; 15(1): 76–83. April 2010.

 

Alpha GPC 300 mg

(3) Parris M. Kidd, PhD; GlyceroPhosphoCholine (GPC); Mind-Body Nutrient for Active Living And Healthy Aging; GPC, Mind-Body Nutrient April 2005 ©P.M. Kidd, PhD ©Science&Ingredients.
(4) Alpha-GPC; Research analysis lead by Kamal Patel; All content reviewed by Examine.com Team. Published: Jul 16, 2013; Last Updated: Sep 16, 2018; https://examine.com/supplements/alpha-gpc/#neurology_dopaminergic-neurotransmission
(5) David Bellar, Nina R. LeBlanc, and Brian Campbell; The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength; Journal of the International Society of Sports Nutrition; 2015; 12: 42.

 

Ashwagandha SE 500 mg

(6) Ruchi Tiwari, Sandip Chakraborty et. Al., "Ashwagandha (Withania somnifera): Role in Safeguarding Health, Immunomodulatory Effects, Combating Infections and Therapeutic Applications: A Review", Journal of Biological Sciences, Volume 14 (2): 77-94, 2014

 

Brain Support

(7) WHO Monographs on Selected Medicinal Plants - Volume 1; (1999; 295 pages) View the PDF document.

 

Ginkgo Biloba 60 mg

(51) WHO Monographs on Selected Medicinal Plants - Volume 1; (1999; 295 pages) View the PDF document.

 

Guarana

(8) Leila Larisa MedeirosMarques; Emilene Dias Fiuza Ferreira; Mariana Nascimento de Paula; Traudi Klein; João Carlos Palazzo de Mello; Paullinia cupana: a multipurpose plant – a review; Revista Brasileira de Farmacognosia; Volume 29, Issue 1, January–February 2019, Pages 77-110.
(9) Natália da Silva Lima, Lucimara Teixeira, Alessandra Gambero, and Marcelo Lima Ribeiro; Guarana (Paullinia cupana) Stimulates Mitochondrial Biogenesis in Mice Fed High-Fat Diet; Nutrients. 2018 Feb; 10(2): 165.

 

L-Carnosine 500 mg

(10) Kirthi Menon, Aya Mousa, Barbora de Courten; Effects of supplementation with carnosine and other histidine-containing dipeptides on chronic disease risk factors and outcomes: protocol for a systematic review of randomized controlled trials; Menon K, et al. BMJ Open 2018;8:e020623. doi:10.1136/bmjopen-2017-020623.
(11) José H Cararo, Emilio L Streck, Patricia F Schuck,1 and Gustavo da C Ferreira, Carnosine and Related Peptides: Therapeutic Potential in Age-Related Disorders; Aging and Disease; 2015 Oct; 6(5): 369–379.

 

L-Glutamine 1000 mg

(12) Bryant J. Jongkees, Maarten A. Immink & Lorenza S. Colzato; Influences of glutamine administration on response selection and sequence learning: a randomized-controlled trial; Scientific Reportsvolume 7, Article number: 2693 (2017).
(13) Michael Stumvoll, Gabriele Perriello, Christian Meyer, John Gerich; Role of glutamine in human carbohydrate metabolism in kidney and other tissues; Kidney International; Volume 55, Issue 3, March 1999, Pages 778-792.
(14) Byrne TA, Wilmore DW, Iyer K, Dibaise J, Clancy K, Robinson MK, Chang P, Gertner JM, Lautz D; Growth hormone, glutamine, and an optimal diet reduces parenteral nutrition in patients with short bowel syndrome: a prospective, randomized, placebo-controlled, double-blind clinical trial; Annals of Surgery; 2005 Nov;242(5):655-61.
(15) Bassini-Cameron, Monteiro A, Gomes A, Werneck-de-Castro JP, Cameron L., ˝Glutamine protects against increases in blood ammonia in football players in an exercise intensity-dependent way.˝, Br J Sports Med. 2008 Apr;42(4):260-6. Epub 2007 Nov 5.
(16) Marc P. McRae, ˝ Therapeutic benefits of glutamine: An umbrella review of meta-analyses˝, Biomed Rep. 2017 May; 6(5): 576–584.

 

Lecithin 1200 mg

(17) Margret I. Moré, Ulla Freitas, and David Rutenberg; Positive Effects of Soy Lecithin-Derived Phosphatidylserine plus Phosphatidic Acid on Memory, Cognition, Daily Functioning, and Mood in Elderly Patients with Alzheimer’s Disease and Dementia; Advances in Therapy; 2014; 31: 1247–1262.
(18) Amouni Mohamed Mourad, Eder de Carvalho Pincinato, Priscila Gava Mazzola, Maricene Sabha, and Patricia Moriel; Clinical Study; Influence of Soy Lecithin Administration on Hypercholesterolemia; Cholesterol; Volume 2010, Article ID 824813, 4 pages.
(19) Nick van Wijk, Martin Balvers, Mehmet Cansev, Timothy J. Maher, John W. C. Sijben, and Laus M. Broerse; Dietary Crude Lecithin Increases Systemic Availability of Dietary Docosahexaenoic Acid with Combined Intake in Rats; Lipids. 2016; 51: 833–846.
(20) Soy lecithin; Research analysis lead by Kamal Patel; All content reviewed by Examine.com Team. Published: Jul 12, 2013; Last Updated: Jun 14, 2018; https://examine.com/supplements/soy-lecithin/#nutrient-nutrient-interactions_absorption-enhancement

 

Memo Rise

(7) WHO Monographs on Selected Medicinal Plants - Volume 1; (1999; 295 pages) View the PDF document.

 

Memory Blend™

(21) Kun Marisa Farhana, Rusdy Ghazali Malueka, Samekto Wibowo, and Abdul Gofir; Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke; Evidence Based Complement Alternative Medicine. 2016; 2016: 2795915.
(22) Hani Choudhrycorresponding and Md. Nasrullah; Iodine consumption and cognitive performance: Confirmation of adequate consumption; Food Science and Nutrition. 2018 Sep; 6(6): 1341–1351.

 

Super Lion's Mane

(32) Junrong Zhang, Shengshu An, Wenji Hu, Meiyu Teng, Xue Wang, Yidi Qu,1 Yang Liu, Ye Yuan, and Di Wang; The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model; International Journal of Molecular Science; 2016 Nov; 17(11): 1810.
(33) Kim SP, Moon E, Nam SH, Friedman M; Hericium erinaceus mushroom extracts protect infected mice against Salmonella Typhimurium-Induced liver damage and mortality by stimulation of innate immune cells; Journal of Agriculture Food Chemistry; 2012 Jun 6;60(22):5590-6

 

Taurine 1000 mg

(30) Harris Ripps and Wen Shen; Review: Taurine: A “very essential” amino acid; Molecular Visios. 2012; 18: 2673–2686.
(31) Xiaoli Niu, Simin Zheng, Hongtao Liu, and Siyuan Li; Protective effects of taurine against inflammation, apoptosis, and oxidative stress in brain injury; Molecular Medicine Reports. 2018 Nov; 18(5): 4516–4522.

 

Train-Your-Brain®

(36) https://pubmed.ncbi.nlm.nih.gov/8709678/
(37) https://examine.com/supplements/cdp-choline/
(38) http://jneuroscience.com/jnen/articles/v5n1/jnen-047-julio-j-secades.pdf
(39) https://examine.com/supplements/bacopa-monnieri/research/#neurology_memory
(40) https://pubmed.ncbi.nlm.nih.gov/12957224/
(41) https://pubmed.ncbi.nlm.nih.gov/22198697/
(42) https://pubmed.ncbi.nlm.nih.gov/29185388/
(43) https://www.frontiersin.org/articles/10.3389/fphar.2017.00849/full
(44) https://pubmed.ncbi.nlm.nih.gov/27100509/
(45) https://www.webmd.com/vitamins-and-supplements/phosphatidylserine-uses-and-risks#1
(46) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258547/
(47) https://www.jstage.jst.go.jp/article/jcbn/47/3/47_10-62/_article
(48) https://www.sciencedirect.com/science/article/pii/S1226845320300567
(49) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930825/#:~:text=The%20role%20of%20pyridoxine%20in,responsible%20for%20the%20synthesis%20of
(50) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/

 

Train-Your-Brain® 9 fiole buvabile

(36) https://pubmed.ncbi.nlm.nih.gov/8709678/
(37) https://examine.com/supplements/cdp-choline/
(38) http://jneuroscience.com/jnen/articles/v5n1/jnen-047-julio-j-secades.pdf
(44) https://pubmed.ncbi.nlm.nih.gov/27100509/
(45) https://www.webmd.com/vitamins-and-supplements/phosphatidylserine-uses-and-risks#1
(46) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258547/
(47) https://www.jstage.jst.go.jp/article/jcbn/47/3/47_10-62/_article
(48) https://www.sciencedirect.com/science/article/pii/S1226845320300567
(49) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930825/#:~:text=The%20role%20of%20pyridoxine%20in,responsible%20for%20the%20synthesis%20of
(50) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/
(51) https://www.mdpi.com/1420-3049/25/4/892
(52) https://www.cardioiliescu.ro/doc/ghid%201_8292_5994.pdf
(53) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275827/
(54) https://www.nature.com/articles/s41598-017-09823-9
(55) https://link.springer.com/article/10.1007/s11101-017-9528-y
(56) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208354/
(57) https://examine.com/supplements/rhodiola-rosea/research/

 

Uridine 250 mg

(58) https://sci-hub.se/10.1073/pnas.0409082102.(59) Research analysis by Kamal Patel and verified by the Examine.com Research Team. Last updated on Jun 14, 2018; Uridine; Examine.com. https://examine.com/supplements/uridine.
(60) https://www.mdpi.com/1422-0067/20/14/3439
(61) https://www.ncbi.nlm.nih.gov/books/NBK218735/#:~:text=Calcium%20is%20the%20momo%20abundant,amount%20is%20found%20in%20bones.
(62) http://neurosurgery.dergisi.org/pdf/pdf_JTN_2479.pdf
(63) https://www.mdpi.com/1422-0067/20/14/3439/htm.

 

Neuro Optimizer® 30 caps si Neuro Optimizer® 60 caps

(23) Sherrill Sellman, ND; The Ultimate Brain Nutrient Cognizin Ctiticoline; http://www.encognitive.com/files/The%20Ultimate%20Brain%20Nutrient%20Cognizin%20Citicoline.pdf
(24) Mario Fioravanti and Ann E.Buckley; Citicoline (Cognizin) in the treatment of cognitive impairment; Clin Interv Aging. 2006 Sep; 1(3): 247–251.
* Efectul produsului Neuro Optimizer ca suport in tratamentul pacientilor cu TCC moderat sau grav constatate sub aspect clinic-observational, retrospectiv in studiul desfasurat, in perioada ianuarie-noiembrie 2015, pe un lot de studiu 38 subiecti raportat la un lot martor de 47 subiecti din perioada 2005-2014, La Spitalul Clinic de Urgenta “Bagdasar-Arseni” (SCUBA), Bucuresti, Romania.
(25) Mikhail Yu Martynov, Eugeny I Gusev, “ Current knowledge on the neuroprotective and neuroregenerative properties of citicoline in acute ischemic stroke”, J Exp Pharmacol. 2015; 7: 17–28.
(26) Alvarez XA, Mouzo R, Pichel V, Pérez P, Laredo M, Fernández-Novoa L, Corzo L, Zas R, Alcaraz M, Secades JJ, Lozano R, Cacabelos R; Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion; Methods Find Exp Clin Pharmacol. 1999 Nov;21(9):633-44.
(27) http://www.purenootropic.com/cholinergics/citicoline/\
(28) Chen J, Herrup K (2012) Glutamine Acts as a Neuroprotectant against DNA Damage, Beta-Amyloid and H2O2-Induced Stress.
(29) Scott D. Mendelson M.D., Ph.D., in Metabolic Syndrome and Psychiatric Illness, 2008.
(30) Harris Ripps and Wen Shen; Review: Taurine: A “very essential” amino acid; Molecular Visios. 2012; 18: 2673–2686.

 

Subsegment: Somn, stres și echilibru emotional

5-HTP

(1) Research analysis lead by Kamal Patel; All content reviewed by Examine.com Team. Published: Jul 21, 2013; Last Updated: Feb 11, 2019; 5-HTP; Examine.com; https://examine.com/supplements/5-htp/#nutrient-nutrient-interactions_l-tyrosine
(2) https://bebrainfit.com/serotonin-supplements/
(3) Birdsall, TC. 5-Hydroxytryptophan: a clinically-e ective serotonin precursor. 1998 Aug;
3(4):271-80.
(4) Massimo E. Ma ei, “ 5-Hydroxytryptophan (5-HTP): Natural Occur ence, Analysis,
Biosynthesis, Biotechnology, Physiology and Toxicology”, Int J Mol Sci. 2021 Jan; 22(1): 181.

 

GABA 750 mg

(5) Evert Boonstra, Roy de Kleijn et. al., "Neurotransmitters as food supplements: the effects of GABA on brain and behavior", Front Psychol. 2015; 6: 1520.
(6) Rachael Link, MS, RD, What Is GABA? The Brain-Boosting, Anxiety-Busting Power of GABA Supplement, November 14, 2017
(7) Pengju Ma, Ting Li, Fanceng Ji, Haibo Wang, and Juntao Pang; Effect of GABA on blood pressure and blood dynamics of anesthetic rats; International Journal of Clinical and Experimental Medicine; 2015; 8(8): 14296–14302.

 

Good-Night

(8) https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002587
(9) https://www.sciencedirect.com/science/article/abs/pii/S0965229919303711
(10) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637834/
(11)https://www.researchgate.net/publication/24198940_Does_valerian_improve_sleepiness_and_symptom_severity_in_people_with_restless_legs_syndrome
(12) https://www.mayoclinic.org/diseases-conditions/insomnia/symptoms-causes/syc-20355167
(13) https://www.ema.europa.eu/en/documents/herbal-summary/valerian-root-hop-strobile-summary-public_en.pdf
(14) https://www.medicalnewstoday.com/articles/323795#what-is-passionflower
(15) Updating the biological interest of Valeriana officinalis Marta Sánchez1 , Elena González Burgos1 , Irene Iglesias1 , M. Pilar Gómez-Serranillos1 Received: 23 June 2020 / Accepted: 5 August 2020 / Published online: 11 January 2021.
(16) https://www.researchgate.net/publication/227185267_Glycine_as_a_neurotransmitter_in_the_forebrain_A_short_review
(17) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930825/#:~:text=The%20role%20of%20pyridoxine%20in,responsible%20for%20the%20synthesis%20of
(18) https://www.medicalnewstoday.com/articles/315372

 

L-Phenylalanine 500 mg

(19) M.LeytonPh.D, S.N.YoungPh.D. et. al., Effects on Mood of Acute Phenylalanine/Tyrosine Depletion in Healthy Women, Neuropsychopharmacology Volume 22, Issue 1, January 2000, Pages 52-63
(20) https://pubchem.ncbi.nlm.nih.gov/compound/L-phenylalanine#section=Top
(21) Siddiqui AH, Stolk LM, Bhaggoe R, et al. L-phenylalanine and UVA irradiation in the treatment of vitiligo. Dermatology 1994;88:215-8.
(22) A Alamshah, E Spreckley et. al., "l-phenylalanine modulates gut hormone release and glucose tolerance, and suppresses food intake through the calcium-sensing receptor in rodents", Int J Obes (Lond). 2017 Nov; 41(11): 1693–1701.

 

L-Theanine 100 mg

(23) Jackson Williams, Jane Kellett, Paul Daniel Roach, Andrew McKune, Duane Mellor, Jackson Thomas and Nenad Naumovski; l-Theanine as a Functional Food Additive: Its Role in Disease Prevention and Health Promotion; Beverages 2016, 2(2), 13; doi:10.3390/beverages2020013.

 

Mag-Your-Mind®

(24)https://www.ncbi.nlm.nih.gov/books/NBK218735/#:~:text=Calcium%20is%20the%20most%20abundant,amount%20is%20found%20in%20bones.
(25) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637834/
(26) https://www.medicalnewstoday.com/articles/315372
(27)https://www.researchgate.net/publication/227185267_Glycine_as_a_neurotransmitter_in_the_forebrain_A_short_review
(28) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208354/
(29) https://examine.com/supplements/rhodiola-rosea/research/
(30) https://examine.com/supplements/schisandra-chinensis/research
(31)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930825/#:~:text=The%20role%20of%20pyridoxine%20in,responsible%20for%20the%20synthesis%20of
(32) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1737896/pdf/v072p00567.pdf
(33) https://pdfs.semanticscholar.org/df3e/c33570bc26330097284c53a4a5c3815be905.pdf
(34) https://www.ncbi.nlm.nih.gov/books/NBK507271/
(35) https://www.acog.org/patient-resources/faqs/gynecologic-problems/premenstrual-syndrome
(36) https://www.sciencedirect.com/science/article/pii/B9780124201682000314

 

Melatonin DropIns 1.5 mg

(37) Samir Malhotra, Girish Sawhney and Promila Pandhi, " The Therapeutic Potential of Melatonin: A Review of the Science", MedGenMed. 2004; 6(2): 46

 

Melatonin 3mg

(37) Samir Malhotra, Girish Sawhney and Promila Pandhi, " The Therapeutic Potential of Melatonin: A Review of the Science", MedGenMed. 2004; 6(2): 46.

 

Passion Flower (Floarea-pasiunii)

(38) Oliver Grundmann, Jie Wang et. al.," Anxiolytic Activity of a Phytochemically Characterized Passiflora incarnata Extract is Mediated via the GABAergic System", Planta Med 2008; 74(15): 1769-1773.
(39) Sita Sharan Patel, Neelesh Kumar Verma et. al., " Passiflora Incarnata Linn: A Review on Morphology, Phytochemistry and Pharmacological Aspects", Phcog Rev. Vol, 3, Issue 5, 175-181, 2009.
(40) Fariba Fahami, Zahra Asali et. al., "A comparative study on the effects of Hypericum Perforatum and passion flower on the menopausal symptoms of women referring to Isfahan city health care centers", Iran J Nurs Midwifery Res. 2010 Autumn; 15(4): 202–207.
(41) http://www.epsihologia.ro/tulburari-de-somn/120-evaluarea-calitatii-somnului.html

 

Sleep Optimizer®

(42) Mendel Friedman, "Analysis, Nutrition, and Health Benefits of Tryptophan", Int J Tryptophan Res. 2018; 11: 1178646918802282.
(43) Sepide Miraj, Rafieian-Kopaei and Sara Kiani, " Melissa officinalis L: A Review Study With an Antioxidant Prospective",
(44) Mendel Friedman, "Analysis, Nutrition, and Health Benefits of Tryptophan", Int J Tryptophan Res. 2018; 11: 1178646918802282.
(45) Malviya, N., Malviya, S., Jain, S., & Vyas, S. (2016). A review of the potential of medicinal plants in the management and treatment of male sexual dysfunction. Andrologia, 48(8), 880–893. doi:10.1111/and.12677

 

St John's Wort 325 mg

(40) Fariba Fahami, Zahra Asali et. al., "A comparative study on the effects of Hypericum Perforatum and passion flower on the menopausal symptoms of women referring to Isfahan city health care centers", Iran J Nurs Midwifery Res. 2010 Autumn; 15(4): 202–207.
(41) http://www.epsihologia.ro/tulburari-de-somn/120-evaluarea-calitatii-somnului.html
(46) Ana I. Oliveira, Cláudia Pinho, Bruno Sarmento and Alberto C. P. Dias; Neuroprotective Activity of Hypericum perforatum and Its Major Components; Frontiers in Plant Science; 11 July 2016 | https://doi.org/10.3389/fpls.2016.01004.
(47) Joanne Barnes, Linda A. Anderson and J. David Phillipson, " St John’s wort (Hypericum perforatumL.) : a review of its chemistry, pharmacology and clinical properties", Journal of Pharmacy and Pharmacology,JPP 2001.
(48) JeromeSarris, AlexanderPanossian et. Al., Herbal medicine for depression, anxiety and insomnia: A review of psychopharmacology and clinical evidence, European Neuropsychopharmacology

 

Super Rhodiola™ 500 mg

(49)http://cms.herbalgram.org/herbalgram/issue56/article2333.html?ts=1561377663&signature=2d0bfe7cca00bf381d1b3107322d6fdf
(50) MaryBove, Jillian E.Stansbury, Aviva Romm, CHAPTER 6 - Endocrine Disorders and Adrenal Support, Botanical Medicine for Women's Health 2010, Pages 186-210.
(51) George M.Kapalka, Nutritional and Herbal Therapies for Children and Adolescents; A Handbook for Mental Health Clinicians, 2010, Pages 141-187.
(52) Abidov M, Crendal F, Grachev S, Seifulla R, Ziegenfuss T, Effect of extracts from Rhodiola rosea and Rhodiola crenulata (Crassulaceae) roots on ATP content in mitochondria of skeletal muscles, Bull Exp Biol Med. 2003 Dec;136(6):585-7.

 

Total Calm™ Advanced

(23) Jackson Williams, Jane Kellett, Paul Daniel Roach, Andrew McKune, Duane Mellor, Jackson Thomas and Nenad Naumovski; l-Theanine as a Functional Food Additive: Its Role in Disease Prevention and Health Promotion; Beverages 2016, 2(2), 13; doi:10.3390/beverages2020013.
(53) Benjamin S Weeks, “ Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian”, Med Sci Monit. 2009 Nov;15(11):RA256-62.

 

Valerian

(54) Michael Yurcheshen, Martin Seehuus and Wilfred Pigeon, "Updates on Nutraceutical Sleep Therapeutics and Investigational Research", Evid Based Complement Alternat Med. 2015; 2015: 105256.
(55) Taavoni Simin MS, Ekbatani Neda BS et. al., "Effect of valerian on sleep quality in postmenopausal women: a randomized placebo-controlled clinical trial", Menopause: September 2011 - Volume 18 - Issue 9 - p 951-955.

 

Magnesium Glycinate ActivGels™

(56) https://mcpress.mayoclinic.org/nutrition-fitness/magnesium-glycinate-is-this-supplement-helpful-for-you/
(57) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637834/
(30) https://examine.com/supplements/schisandra-chinensis/research
(28) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208354/
(29) https://examine.com/supplements/rhodiola-rosea/research/
(35) https://www.acog.org/patient-resources/faqs/gynecologic-problems/premenstrual-syndrome
(25) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637834/
(58) https://www.tandfonline.com/doi/full/10.1080/1028415X.2021.1945859?casa_token=SDQ7LdNV9ToAAAAA%3AMuEZr-vVumKWLUehTrOB9XpKKmobXbAUQlaJDTbzeR9gPu78lgNUgWj8ac9YM3JNxbTNuKyn5rOPWJOb
(59) Lisa A. Yablon and Alexander Mauskop, ˝ Magnesium in headache˝, Magnesium in the Central Nervous System, Adelaide (AU): University of Adelaide Press; 2011.
(60) Magdalena D. Cuciureanu and Robert Vink, ˝ Magnesium and stress˝, Magnesium in the Central Nervous System, Adelaide (AU): University of Adelaide Press; 2011.
(36) https://www.sciencedirect.com/science/article/pii/B9780124201682000314
(61) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703169/
(62) https://pubmed.ncbi.nlm.nih.gov/8509592/
(63) https://pubmed.ncbi.nlm.nih.gov/28392498/
(64). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045762/
(65) https://www.sciencedirect.com/science/article/abs/pii/S875632822100048X
(66) https://pubmed.ncbi.nlm.nih.gov/17063625/
(67) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313472/
(68) https://www.ncbi.nlm.nih.gov/books/NBK541123/
(69) https://www.mdpi.com/2072-6643/13/11/4074
(70) https://www.mdpi.com/2072-6643/13/4/1136
(71) https://pubmed.ncbi.nlm.nih.gov/18516713/
(72) https://www.sciencedirect.com/science/article/pii/S2213231722000854
(73) https://www.sciencedirect.com/science/article/abs/pii/S0272638612806676

 

Migra Defense™

(74) https://www.mayoclinic.org/diseases-conditions/migraine-headache/symptoms-causes/syc-20360201

(75) D. Palevitch, G. Earon, R. Carasso, " Feverfew (Tanacetum parthenium) as a prophylactic treatment for migraine: a double‐blind placebo‐  controlled study", Phytotherapy Research

(76) Anil Pareek, Manish Suthar, Garvendra S. Rathore, and Vijay Bansal; Feverfew (Tanacetum parthenium L.): A systematic review; Pharmacognosy review; 2011 Jan-Jun; 5(9): 103–110.

 

Pediatrie

 

Baby's Jarro-Dophilus® + GOS

(3) Paulina Markowiak and Katarzyna Śliżewska; Effects of Probiotics, Prebiotics, and Synbiotics on Human Health; Nutrients. 2017 Sep; 9(9): 1021.
(4)https://www.morinagamilk.co.jp/english/research/r_and_d/bifidobacteria/
(5)https://lallemand-health-solutions.com/en/
(6) David Groeger, Liam O’Mahony, Eileen F. Murphy, John F. Bourke, Timothy G. Dinan, Barry Kiely, Fergus Shanahan, and Eamonn M.M. Quigley; Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut; Gut Microbes. 2013 Jul 1; 4(4): 325–339.

 

Aller-Care

(1)  Poonam Arora, S. H. Ansari, Abul Kalam Najmi, Varisha Anjum and Sayeed Ahmad; Investigation of anti-asthmatic potential of dried fruits of Vitis vinifera L. in animal model of bronchial asthma; Allergy, Asthma & Clinical Immunology2016.
(2) Décio Medeiros Peixoto; José Angelo Rizzo; Deborah Schor; Almerinda Rêgo Silva; Dinaldo Cavalcanti de Oliveira; Dirceu Solé; Emanuel Sarinho; Use of honey associated with Ananas comosus (Bromelin) in the treatment of acute irritative cough; Revista Paulista de Pediatria; vol.34 no.4 São Paulo Oct./Dec. 2016.

 

Calcium with Magnesium 473 ml

(7)  Jan Philipp Schuchardt and Andreas Hahn; Intestinal Absorption and Factors Influencing Bioavailability of Magnesium-An Update; Current Nutrition and Food Science; 2017 Nov; 13(4): 260–278.
(8)  Hanzlik RP, Fowler SC, Fisher DH.; Relative bioavailability of calcium from calcium formate, calcium citrate, and calcium carbonate; J Pharmacol Exp Ther. 2005 Jun;313(3):1217-22. Epub 2005 Feb 25.
(9) Barrie SA, Wright JV, Pizzorno JE, Kutter E, Barron PC.; Agents Actions. 1987 Jun;21(1-2):223-8.; Comparative absorption of zinc picolinate, zinc citrate and zinc gluconate in humans.

 

ChildBiotics Immune Digestive Support

(1) https://pubmed.ncbi.nlm.nih.gov/31271261/
(2) https://www.chr-hansen.com/en/human-health-and-probiotics/our-probiotic-strains/dds
(3) https://www.chr-hansen.com/en/human-health-and-probiotics/our-probiotic-strains/uabla-12
(4) https://www.casi.org/node/1414

(5) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099657/

(6) https://www.chr-hansen.com/en/human-health-and-probiotics/our-probiotic-strains

(7) Chiara Mazziotta,Mauro Tognon et. Al., “ Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health”, Cells 2023, 12(1), 184; https://doi.org/10.3390/cells12010184
(73) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692339/

 

Colostrum with Probiotics

(10) Kehoe S, Jayarao BM, Heinrichs A.; A survey of bovine colostrum composition and colostrum management practices on Pennsylvania dairy farms.; Journal of Dairy Science; 2007 Sep;90(9):4108-16.
(11) Paulina Markowiak and Katarzyna Śliżewska; Effects of Probiotics, Prebiotics, and Synbiotics on Human Health; Nutrients. 2017 Sep; 9(9): 1021.
(12) Harpal S.Buttar; Siddhi M.Bagwe; Sukhwinder K.Bhullar; GinpreetKaur; Chapter 1 - Health Benefits of Bovine Colostrum in Children and Adults; Dairy in Human Health and Disease Across the Lifespan; 2017, Pages 3-20.
(13) Ivana Nikolic; Ivana Stojanovic; Milica Vujicic; Paolo Fagone; Katia Mangano; Stanislava Stosic-Grujicic; Ferdinando Nicoletti; Tamara Saksid, PhDa; Standardized bovine colostrum derivative impedes development of type 1 diabetes in rodents; Immunobiology; Volume 222, Issue 2, February 2017, Pages 272-279.

 

Colostrum with Probiotics Chewable Tabs

(10) Kehoe S, Jayarao BM, Heinrichs A.; A survey of bovine colostrum composition and colostrum management practices on Pennsylvania dairy farms.; Journal of Dairy Science; 2007 Sep;90(9):4108-16.
(11) Paulina Markowiak and Katarzyna Śliżewska; Effects of Probiotics, Prebiotics, and Synbiotics on Human Health; Nutrients. 2017 Sep; 9(9): 1021.
(12) Harpal S.Buttar; Siddhi M.Bagwe; Sukhwinder K.Bhullar; GinpreetKaur; Chapter 1 - Health Benefits of Bovine Colostrum in Children and Adults; Dairy in Human Health and Disease Across the Lifespan; 2017, Pages 3-20.
(13) Ivana Nikolic; Ivana Stojanovic; Milica Vujicic; Paolo Fagone; Katia Mangano; Stanislava Stosic-Grujicic; Ferdinando Nicoletti; Tamara Saksid, PhDa; Standardized bovine colostrum derivative impedes development of type 1 diabetes in rodents; Immunobiology; Volume 222, Issue 2, February 2017, Pages 272-279.

 

Cough Syrup

(14)     Pharmacodynamic Basis of Herbal Medicine Second Edition; Manuchair Ebadi; CRC Press, 6 sept. 2006 - 699 pagini; pg. 137-138.
(15)     David Hoffmann, FNIMH, AHG; Medical Herbalism, The Science and Practice of Herbal Medicine; pg. 575, 580, 2003.
(16)     Herbal approaches to system dysfunctions; Principles and Practice of Phytotherapy (Second Edition); Modern Herbal Medicine; 2013, Pages 183-350.

 

Echinacea (copii)

(17) Joanne Barnes, Linda A. Anderson, Simon Gibbons and J. David Phillipson, "Echinacea species (Echinacea angustifolia (DC.) Hell.,Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.)Moench): a review of their chemistry, pharmacology and clinical properties", Journal of Pharmacy and Pharmacology, JPP 2005, 57: 929–954.

 

Elderberry Super-Immune SoftChew Gummies™

(18) Mohaddese Mahboubi, “ Sambucus nigra (black elder) as alternative treatment for cold and flu”, ADV TRADIT MED (ADTM). 2020 Jul 10 : 1–10.
(19) Donald J. Cox, PhD, „ Introducing Wellmune®, an immune health ingredient”, Kerry Health and Nutrition Institute
(20)Michalina Bartak, Agata Lange, Anna Słońska, Joanna Cymerys, “ Antiviral and healing potential of Sambucus nigra extracts”, Volumen 5 / Número 3, http://www.revistabionatura.com

 

First Defense

(21) M. Składanowski, P. GolinskA, K Rudnicka, H. Dahm, M. Rai; Evaluation of cytotoxicity, immune compatibility and antibacterial activity of biogenic silver nanoparticles; Medical Microbiology and Immunology; December 2016, Volume 205, Issue 6, pp 603–61.
(22) Yueh-Hsia Luo, Louis W. Chang, and Pinpin Lin; Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications; BioMed Research International; Volume 2015, Article ID 143720, 12 pages.
(23) Morones-Ramirez, Jose Ruben, Winkler, Jonathan A., Spina, Catherine S., and Collins, James J. “Silver Enhances Antibiotic Activity Against Gram-Negative Bacteria.” Science Translational Medicine 2013 19 Jun; 5(190): 190ra81.
(24) Massimiliano Francesco Peana, Valeria Marina Nurchi and Maria Antonietta Zoroddu, “ The medical uses of silver: history, myths and scientific evidence”, J. Med. Chem., DOI: 10.1021/acs.jmedchem.8b01439 • Publication Date (Web): 08 Feb 2019

 

Gripe Water

(25) Shanthi G. Parkar, Doug Rosendale et. al., ‘’In vitro Utilization of Gold and Green Kiwifruit Oligosaccharides by Human Gut Microbial Populations’’, Plant Foods for Human Nutrition, September 2012, Volume 67, Issue 3, pp 200–207.
(26) Irina Alexandrovich, Olga  Rakovitskaya et. al., ‘’ The effect of fennel (Foeniculum vulgare) seed oil emulsion in infantile colic: A randomized, placebo-controlled study’’, Alternative Therapies in Health and Medicine; Aliso Viejo Vol. 9, Iss. 4,  (Jul/Aug 2003): 58-61.

 

Healthy Vision SoftMelts™

(27) Keyvan Koushan, Raluca Rusovici, Wenhua Li, Lee R. Ferguson, and Kakarla V. Chalam. The Role of Lutein in Eye-Related Disease. Nutrients. 2013 May; 5(5): 1823–1839.
(28) Justyna Widomska , John Paul SanGiovanni, and Witold K. Subczynski. Why Is Zeaxanthin the Most Concentrated Xanthophyll in the Central Fovea? Published: 7 May 2020
(29) Tatania K. Emmick and Diane Alexander, Ph.D. Why Dietary Zeaxanthin? - A Scientific Summary. Kemin Industries, Inc. and its group of companies 2013.
(30) Silvio Buscemi, Davide Corleo, Francesco Di Pace, Maria Letizia Petroni, Angela Satriano, and Giulio Marchesini. The Effect of Lutein on Eye and Extra-Eye Health. Nutrients. 2018 Sep; 10(9): 1321.
(31) Kvansakul J, Rodriguez-Carmona M, Edgar DF, Barker FM, Köpcke W, Schalch W, Barbur JL; Supplementation with the carotenoids lutein or zeaxanthin improves human visual performance; Ophthalmic Physiol Opt. 2006 Jul;26(4):362-71.
(32)https://www.ebmconsult.com/articles/vitamin-a-eye-vision-mechanism
(33) Seong Hee Shim, Joon Mo Kim, Chul Young Choi, Chan Yun Kim, and Ki Ho Park. Ginkgo biloba Extract and Bilberry Anthocyanins Improve Visual Function in Patients with Normal Tension Glaucoma. J Med Food. 2012 Sep; 15(9): 818–823.

  

Hepato-Care

(34) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Jun 13, 2014; Last Updated: Jun 14, 2018; https://examine.com/supplements/inositol/
(35) Nora M. Griffiths , R. D. H. Stewart , Marion F. Robinson,"The metabolism of [75Se]selenomethionine in four women", Published online: 25 March 2008.
(36) Flora K1, Hahn M, Rosen H, Benner K; Milk thistle (Silybum marianum) for the therapy of liver disease; American Journal of Gastroenterology; 1998 Feb;93(2):139-43.
(37) Chan YS, Cheng LN, Wu JH, Chan E, Kwan YW, Lee SM, Leung GP, Yu PH, Chan SW; A review of the pharmacological effects of Arctium lappa (burdock); Inflammopharmacology. 2011 Oct;19(5):245-54. doi: 10.1007/s10787-010-0062-4. Epub 2010 Oct 28.
(38) Assessment report on Taraxacum officinale Weber ex; Wigg., radix cum herba; 12 November 2009; EMA/HMPC/212897/2008; Committee on Herbal Medicinal Products (HMPC).
(39) Asghar Farghi Yamchi; Mansour Dabirzadeh; Abdolhossein Miri; Effects of Methanolic Extract of Arctium lappa Root on Promastigotes and Amastigotes of Leishmania major (in vitro); September 2016 with 24 Reads; DOI: 10.18869/acadpub.mlj.10.5.50.

 

Jarro-Dophilus® Infant

(40) Mark A. Underwood, J. Bruce German, Carlito B. Lebrilla and David A. Mills, ˝ Bifidobacterium longum subspecies infantis: champion colonizer of the infant gut˝, Pediatr Res. 2015 Jan; 77(0): 229–235.
(41) Paulina Markowiak and Katarzyna Śliżewska; Effects of Probiotics, Prebiotics, and Synbiotics on Human Health; Nutrients. 2017 Sep; 9(9): 1021.

 

Liquid Iron 10mg

(42) ‘’Ferrous bisglycinate as a source of iron for use in the manufacturing of foods and in food supplements’’, The EFSA Journal (2006) 299, 1-17.
(43) Seria Protocoale în îngrijirea anemiei și rahitismului la copil, Ministerul Sănătății, Institutul pentru Ocrotirea Mamei și Copilului, ‘’Prof. Dr. Alfred Rusescu’’.
(44) https://www.synevo.ro/shop/feritina/

 

Multi Vitamin & Mineral

(45) https://www.naturalproductsinsider.com/vitamins-minerals/proper-nutrition-birth-age-8-forms-strong-foundation-growth-and-wellness

 

Para-Defense

(48) Mohamed Fizur Nagoor Meeran,Hayate Javed et. Al., " Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development", Front Pharmacol. 2017; 8: 380.
(49) Eqbal M. A. Dauqan, Aminah Abdullah, " Medicinal and Functional Values of Thyme (Thymus vulgaris L.) Herb", Journal of Applied Biology & Biotechnology Vol. 5 (02), pp. 017-022, March-April, 2017
(50) Maciej Grzybek, Wirginia Kukula-Koch et. al., ˝Evaluation of Anthelmintic Activity and Composition of Pumpkin (Cucurbita pepo L.) Seed Extracts—In Vitro and in Vivo Studies˝, Int. J. Mol. Sci. 2016, 17(9), 1456; doi:10.3390/ijms17091456
(51) Jing-Yang Wong, Mahmood Ameen Abdulla et. al., ˝Gastroprotective Effects of Lion’s Mane Mushroom Hericium erinaceus (Bull.:Fr.) Pers. (Aphyllophoromycetideae) Extract against Ethanol-Induced Ulcer in Rats˝, Evidence-Based Complementary and Alternative Medicine, Volume 2013, Article ID 492976
(52) Leyla Bayan, Peir Hossain Koulivand and Ali Gorji, " Garlic: a review of potential therapeutic effects", Avicenna J Phytomed. 2014 Jan-Feb; 4(1): 1–14.

 

Pure DHA

(53) https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/

 

Toothpaste Tablets

(54) Domen Kanduti,  Petra Sterbenk,  Barbara Artnik, "FLUORIDE: A REVIEW OF USE AND EFFECTS ON HEALTH", Mater Sociomed. 2016 Apr; 28(2): 133–137.
(55) StefanoPetti, CrispianScully, "Polyphenols, oral health and disease: A review",Journal of Dentistry, Volume 37, Issue 6, June 2009, Pages 413-423
(56) Bonifait L , Grenier D ," Cranberry polyphenols: potential benefits for dental caries and periodontal disease", Journal (Canadian Dental Association) [01 Jan 2010, 76:a130]

 

Vitamin C 250mg (copii)

(57) Khalid Iqbal, Alam Khan et. al., "Biological Significance of Ascorbic Acid( Vitamin C) in Human Health- A Review", Pakistan Journal of Nutrition 3(1):5-13, 2004

 

Vitamin D3 500UI (copii)

(58) Seria Protocoale în îngrijirea anemiei și rahitismului la copil, Ministerul Sănătății, Institutul pentru Ocrotirea Mamei și Copilului, ‘’Prof. Dr. Alfred Rusescu’’.

 

Vitamin K2 (copii) 15 mcg

59) Leon J. Schurgers, Kirsten J. F. Teunissen et. al., ‘’Vitamin K–containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7’’, The American Society of Hematology, 2007
(60) Gerry Kurt Schwalfenberg, " Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health", J Nutr Metab. 2017; 2017: 6254836.

 

Zinc Plus 118 ml

(61) Batool A. Haider and Zulfiqar A. Bhutta, “ The effect of therapeutic zinc supplementation among young children with selected infections: A review of the evidence”, Food and Nutrition Bulletin, vol. 30, no. 1 (supplement) © 2009, The United Nations University.
(62) https://naturopathicpediatrics.com/2022/08/23
(63) Wegmüller et al. (2014) Zinc Absorption by Young Adults from Supplemental Zinc Citrate Is comparable with That from Zinc Gluconate and Higher than from Zinc Oxide. J. Nutr. 144: 132–136, 2014.
(64) Karrera Y. Djoko, Cheryl-lynn Y. Ong, Mark J. Walker and Alastair G. McEwan, The Role of Copper and Zinc Toxicity in Innate Immune Defense against Bacterial Pathogens*, THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 290, NO. 31, pp. 18954 –18961, July 31, 2015, © 2015 by The American Society for Biochemistry and Molecular Biology, Inc. Published in the U.S.A.

 

Sleep Essential

(65) https://www.medicalnewstoday.com/articles/lemon-balm-uses#_noHeaderPrefixedContent
(66)https://www.nursingcenter.com/journalarticle?Article_ID=3220809&Journal_ID=54004&Issue_ID=3220444
(67) https://boisenaturalhealth.com/l-theanine-a-supplement-for-children-and-adults-with-anxiety-and-trouble-focusing/
(68) https://www.deimossrl.it/en/aethra-en/etas-an-innovative-asparagus-extract/
(69) https://nutriscienceusa.com/insight/scientific-assessment-of-the-synergistic-effects-of-l-theanine-and-ashwagandha/
(70) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805132/
(71) https://www.sciencedirect.com/science/article/abs/pii/S0944711304701142
(72) https://www.aafp.org/pubs/afp/issues/2014/0301/p368.html

 

Sistemul gastrointestinal

Subsegment: Probiotice & prebiotice

 

Jarro-Dophilus®+FOS 30 cps

(3) Joanne Slavin, Fiber and Prebiotics: Mechanisms and Health Benefits, Nutrients. 2013 Apr; 5(4): 1417–1435.
(4) Marcel B Roberfroid, The American Journal of Clinical Nutrition, Volume 71, Issue 6, 1 June 2000, Pages 1682S–1687S, https://doi.org/10.1093/ajcn/71.6.1682S.
(5) Harish K, Varghese T, Probiotics in humans-evidence based review, Calicut Medical Journal 2006;4(4):e3, India.
(6) Z. ZALÁN et al.: Hydrogen Peroxide and Bacteriocin Production of Lactobacillus spp., Food Technol. Biotechnol. 43 (3) 219–225 (2005).
(7) Qing Gu and Ping Li (July 13th 2016). Biosynthesis of Vitamins by Probiotic Bacteria, Probiotics and Prebiotics in Human Nutrition and Health, Venketeshwer Rao and Leticia G. Rao, IntechOpen, DOI: 10.5772/63117.
(8) https://dexonline.ro/definitie/biotic

 

Jarro-Dophilus + FOS 100 caps veg

(3) Joanne Slavin, Fiber and Prebiotics: Mechanisms and Health Benefits, Nutrients. 2013 Apr; 5(4): 1417–1435.
(4) Marcel B Roberfroid, The American Journal of Clinical Nutrition, Volume 71, Issue 6, 1 June 2000, Pages 1682S–1687S, https://doi.org/10.1093/ajcn/71.6.1682S.
(5) Harish K, Varghese T, Probiotics in humans-evidence based review, Calicut Medical Journal 2006;4(4):e3, India.
(6) Z. ZALÁN et al.: Hydrogen Peroxide and Bacteriocin Production of Lactobacillus spp., Food Technol. Biotechnol. 43 (3) 219–225 (2005).
(7) Qing Gu and Ping Li (July 13th 2016). Biosynthesis of Vitamins by Probiotic Bacteria, Probiotics and Prebiotics in Human Nutrition and Health, Venketeshwer Rao and Leticia G. Rao, IntechOpen, DOI: 10.5772/63117.
(8) https://dexonline.ro/definitie/biotic

 

Jarro-Dophilus® EPS

(3) Joanne Slavin, Fiber and Prebiotics: Mechanisms and Health Benefits, Nutrients. 2013 Apr; 5(4): 1417–1435.
(4) Marcel B Roberfroid, The American Journal of Clinical Nutrition, Volume 71, Issue 6, 1 June 2000, Pages 1682S–1687S, https://doi.org/10.1093/ajcn/71.6.1682S.
(5) Harish K, Varghese T, Probiotics in humans-evidence based review, Calicut Medical Journal 2006;4(4):e3, India.
(6) Z. ZALÁN et al.: Hydrogen Peroxide and Bacteriocin Production of Lactobacillus spp., Food Technol. Biotechnol. 43 (3) 219–225 (2005).
(8) https://dexonline.ro/definitie/biotic
(9) J. M. Andrews, M. Tan, Probiotics in the luminal gastroenterology: the current state of play, Internal Medicine Journal, published 18.12. 2012.
(10) Corliss A O’ Bryan, Dolar Pak, Philip G Crandall, Sun Ok Lee and Steven C Ricke, The Role of Prebiotics and Probiotics in Human Health, J Prob Health 2013, Vol 1(2): 108.

 

Jarro-Dophilus® Ultra

(5) Harish K, Varghese T, Probiotics in humans-evidence based review, Calicut Medical Journal 2006;4(4):e3, India.
(6) Z. ZALÁN et al.: Hydrogen Peroxide and Bacteriocin Production of Lactobacillus spp., Food Technol. Biotechnol. 43 (3) 219–225 (2005).
(7) Qing Gu and Ping Li (July 13th 2016). Biosynthesis of Vitamins by Probiotic Bacteria, Probiotics and Prebiotics in Human Nutrition and Health, Venketeshwer Rao and Leticia G. Rao, IntechOpen, DOI: 10.5772/63117.
(8) https://dexonline.ro/definitie/biotic
(10) Corliss A O’ Bryan, Dolar Pak, Philip G Crandall, Sun Ok Lee and Steven C Ricke, The Role of Prebiotics and Probiotics in Human Health, J Prob Health 2013, Vol 1(2): 108.
(12) Nicole Bozzi Cionci, Loredana Baffoni, Francesca Gaggìa, and Diana Di Gioia; Therapeutic Microbiology: The Role of Bifidobacterium breve as Food Supplement for the Prevention/Treatment of Paediatric Diseases; Nutrients. 2018 Nov; 10(11): 1723; Published online 2018 Nov 10.
(13) Mitsuyuki Matsuo; Kazuhiko Arimori; Chizuko Nakamura; Masahiro Nakano; Delayed-release tablets using hydroxyethylcellulose as a gel-forming matrix; International Journal of Pharmaceutics; Volume 138, Issue 2, 26 July 1996, Pages 225-235.
(14) Muhammad Usman Ghori; Barbara R Conway; Hydrophilic Matrices for Oral Control Drug Delivery; December 2015.

 

Prebiotic XOS+α-GOS

(1) Paiboon Thammarutwasik, Tipparat Hongpattarakere, "Prebiotics – A Review", Songklanakarin J. Sci. Technol.31 (4), 401-408, Jul. - Aug. 2009.
(2) Glenn R. Gibson, Marcel B. Roberfroid, " Handbook of Prebiotics".

 

Saccharomyces Boulardii + MOS

(4) Marcel B Roberfroid, The American Journal of Clinical Nutrition, Volume 71, Issue 6, 1 June 2000, Pages 1682S–1687S, https://doi.org/10.1093/ajcn/71.6.1682S.
(5)    Harish K, Varghese T, Probiotics in humans-evidence based review, Calicut Medical Journal 2006;4(4):e3, India.
(9) J. M. Andrews, M. Tan, Probiotics in the luminal gastroenterology: the current state of play, Internal Medicine Journal, published 18.12. 2012.
(11) Seema Patel, Arun Goyal, The current trends and future perspectives of prebiotics research: a review, 3 Biotech. 2012 Jun; 2(2): 115–125.

 

Synergize-Your-Gut® 30 caps veg (DRcaps) si Synergize-Your-Gut 10 caps veg (DRcaps)

(15) https://www.mayoclinic.org/drugs-supplements-acidophilus/art-20361967
(16) Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black RE. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. Lancet Infect Dis. 2006;6(6):374-382. doi:10.1016/S1473-3099(06)70495-9

(17)Mezzasalma V, Manfrini E, Ferri E, et al. Orally administered multispecies probiotic formulations to prevent uro-genital infections: a randomized placebo-controlled pilot study [published correction appears in Arch Gynecol Obstet. 2017 Feb;295(2):527]. Arch Gynecol Obstet. 2017;295(1):163-172. doi:10.1007/s00404-016-4235-2
(18) Douillard FP, Ribbera A, Kant R, et al. Comparative genomic and functional analysis of 100 Lactobacillus rhamnosus strains and their comparison with strain GG. PLoS Genet. 2013;9(8):e1003683. doi:10.1371/journal.pgen.1003683
(19) Ruszczyński M, Radzikowski A, Szajewska H. Clinical trial: effectiveness of Lactobacillus rhamnosus (strains E/N, Oxy and Pen) in the prevention of antibiotic-associated diarrhoea in children. Aliment Pharmacol Ther. 2008;28(1):154-161. doi:10.1111/j.1365-2036.2008.03714.x
(20) Hill D, Sugrue I, Tobin C, Hill C, Stanton C, Ross RP. The Lactobacillus casei Group: History and Health Related Applications. Front Microbiol. 2018;9:2107. Published 2018 Sep 10. doi:10.3389/fmicb.2018.02107
(21) Cai H, Thompson R, Budinich MF, Broadbent JR, Steele JL. Genome sequence and comparative genome analysis of Lactobacillus casei: insights into their niche-associated evolution. Genome Biol Evol. 2009;1:239-257. Published 2009 Jul 14. doi:10.1093/gbe/evp019
(22) Behera SS, Ray RC, Zdolec N. Lactobacillus plantarum with Functional Properties: An Approach to Increase Safety and Shelf-Life of Fermented Foods. Biomed Res Int. 2018;2018:9361614. Published 2018 May 28. doi:10.1155/2018/9361614
(23) Badet C, Thebaud NB. Ecology of lactobacilli in the oral cavity: a review of literature. Open Microbiol J. 2008;2:38-48. doi:10.2174/1874285800802010038
(24) Kurt Selle, Todd R. Klaenhammer, Genomic and phenotypic evidence for probiotic influences of Lactobacillus gasseri on human health, FEMS Microbiology Reviews, Volume 37, Issue 6, November 2013, Pages 915–935, https://doi.org/10.1111/1574-6976.12021
(25) Stoeker L, Nordone S, Gunderson S, et al. Assessment of Lactobacillus gasseri as a candidate oral vaccine vector. Clinical and Vaccine Immunology : CVI. 2011 Nov;18(11):1834-1844. DOI: 10.1128/cvi.05277-11.
(26) Chyn Boon Wong, Toshitaka Odamaki, Jin-zhong Xiao, Insights into the reason of Human-Residential Bifidobacteria (HRB) being the natural inhabitants of the human gut and their potential health-promoting benefits, FEMS Microbiology Reviews, Volume 44, Issue 3, May 2020, Pages 369–385, https://doi.org/10.1093/femsre/fuaa010
(27) Corrêa NB, Péret Filho LA, Penna FJ, Lima FM, Nicoli JR. A randomized formula controlled trial of Bifidobacterium lactis and Streptococcus thermophilus for prevention of antibiotic-associated diarrhea in infants. J Clin Gastroenterol. 2005;39(5):385-389. doi:10.1097/01.mcg.0000159217.47419.5b
(28) MacSharry J, O'Mahony C, Shalaby KH, et al. Immunomodulatory effects of feeding with Bifidobacterium longum on allergen-induced lung inflammation in the mouse. Pulm Pharmacol Ther. 2012;25(4):325-334. doi:10.1016/j.pupt.2012.05.011
(29) Muhammad Shoaiba, Aamir Shehzada, et. Al., Inulin: Properties, health benefits and food applications, Carbohydrate Polymers, Volume 147, 20 August 2016, Pages 444-454
(30) Cukrowska B, Bierła JB, Zakrzewska M, Klukowski M, Maciorkowska E. The Relationship between the Infant Gut Microbiota and Allergy. The Role of Bifidobacterium breve and Prebiotic Oligosaccharides in the Activation of Anti-Allergic Mechanisms in Early Life. Nutrients. 2020;12(4):946. Published 2020 Mar 29. doi:10.3390/nu12040946
(4) Marcel B Roberfroid, The American Journal of Clinical Nutrition, Volume 71, Issue 6, 1 June 2000, Pages 1682S–1687S, https://doi.org/10.1093/ajcn/71.6.1682S.
(5) Harish K, Varghese T, Probiotics in humans-evidence based review, Calicut Medical Journal 2006;4(4):e3, India. Jarro lactoza
(31)Carlos López-Otín and Judith S. Bond; Proteases: Multifunctional Enzymes in Life and Disease; Journal of Biological Chemistry; 2008 Nov 7; 283(45): 30433–30437; doi: 10.1074/jbc.R800035200. (sursa noua de la galactoza, enzime)
(32) https://www.sciencedirect.com/science/article/abs/pii/S0023643820303224
(33) https://www.mdpi.com/2076-2607/10/12/2332
(34) https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/human-studies-with-probiotics-and-prebiotics-clinical-implications/54B396355BF8559C9EBE5D39F5C30D84
(35) https://www.sciencedirect.com/science/article/pii/S0022030295767844
(36) https://www.sciencedirect.com/science/article/pii/S245201441930007X?via%3Dihub
(37) https://bmjopen.bmj.com/content/9/3/e017995.abstract
(38) https://emjreviews.com/wp-content/uploads/sites/2/2017/10/Role-of-Probiotics....pdf
(39) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139795
(40) https://www.tandfonline.com/doi/full/10.3109/07853890.2015.1071872
(41) https://www.tandfonline.com/doi/full/10.1080/19490976.2020.1801944
(42) https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-017-0691-z?report=reader
(43) https://japsonline.com/admin/php/uploads/1280_pdf.pdf
(44) https://sci-hub.ru/https://www.tandfonline.com/doi/abs/10.1080/19440049.2014.943304
(45) https://www.frontiersin.org/articles/10.3389/fmicb.2021.655705/full
(46) https://www.mdpi.com/2072-6643/13/9/3061
(47) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753912/
(48) https://www.mdpi.com/2227-9059/10/2/436
(49)https://journals.lww.com/jcge/Abstract/2017/04000/Probiotics_for_Preventing_and_Treating_Small.4.aspx
(50) https://www.sciencedirect.com/science/article/pii/S2052297521000512?via%3Dihub
(51) https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD008831.pub3/full
(52) https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-017-0691-z?report=reader
(53) https://www.tandfonline.com/doi/full/10.1080/87559129.2023.2172426
(54) https://www.sciencedirect.com/science/article/abs/pii/S0144861720312893?via%3Dihub
(55) https://link.springer.com/article/10.1007/s00394-017-1568-y
(56) https://link.springer.com/article/10.1007/s12602-017-9322-6
(57) https://www.jmbfs.org/issue/february-march-2015-vol-4-no-3/jmbfs-0718-kumar/?issue_id=3694&article_id=8
(58) https://www.mdpi.com/2673-8449/1/2/6
(59) https://sci-hub.ru/https://doi.org/10.1111/j.1440-1754.2007.01076.x
(60) https://sci-hub.ru/https://link.springer.com/article/10.1007/s11274-013-1499-6
(61) https://jamanetwork.com/journals/jama/fullarticle/1151505
(62) https://sci-hub.ru/https://doi.org/10.1016/j.vaccine.2013.11.053
(63)https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/probiotics-beneficial-factors-of-the-defence-system/EF4FDDF22D9E1317912B742C2B79BE20
(64) https://link.springer.com/article/10.1007/s00240-010-0262-9

Subsegment: Enzime

 

Bromelain 500mg

(13) Rajendra Pavan, Sapna Jain, Shraddha, and Ajay Kumar; Properties and Therapeutic Application of Bromelain: A Review; Biotechnology Research International; 2012; 2012: 976203; Published online 2012 Dec 10. doi: 10.1155/2012/976203.

 

Gluten Enzymes

(1) Carlos López-Otín and Judith S. Bond; Proteases: Multifunctional Enzymes in Life and Disease; Journal of Biological Chemistry; 2008 Nov 7; 283(45): 30433–30437; doi: 10.1074/jbc.R800035200.
(2) R Aravindan, P Anbumathi and T Viruthagiri; Lipase applications in food industry; Indian Journal of Biotechnology; Vol 6, April 2007, pp 141-158.
(3) Rejane Mattar, Daniel Ferraz de Campos Mazo, and Flair José Carrilho; Lactose intolerance: diagnosis, genetic, and clinical factors; Clinical and Experimental Gastroenterology; 2012; 5: 113–121; Published online 2012 Jul 5. doi: 10.2147/CEG.S32368.
(4) Shaima Saqib, Attiya Akram, Sobia Ahsan Halim and Raazia Tassaduq; Sources of β-galactosidase and its applications in food industry; 3 Biotech. 2017 May; 7(1): 79. Published online 2017 May 12. doi: 10.1007/s13205-017-0645-5.
(5) Robert F. H. Dekker; Hemicellulases: Their Occurrence, Purification, Properties, and Mode of Action; Advances in Carbohydrate Chemistry and Biochemistry · February 1976.
(6) BY DR. BRAD RACHMAN; Unique Features and Application of Non-Animal Derived Enzymes; CNI510 8/97; CLINICAL NUTRITION INSIGHTS; Copyright ® 1997 by Advanced Nutrition Publications, Inc.; Vol. 5, No. 10.

 

Lactase™ Enzymes

(3) Rejane Mattar, Daniel Ferraz de Campos Mazo, and Flair José Carrilho; Lactose intolerance: diagnosis, genetic, and clinical factors; Clinical and Experimental Gastroenterology; 2012; 5: 113–121; Published online 2012 Jul 5. doi: 10.2147/CEG.S32368.

 

Super Enzymes™

(2) R Aravindan, P Anbumathi and T Viruthagiri; Lipase applications in food industry; Indian Journal of Biotechnology; Vol 6, April 2007, pp 141-158.
(3) Rejane Mattar, Daniel Ferraz de Campos Mazo, and Flair José Carrilho; Lactose intolerance: diagnosis, genetic, and clinical factors; Clinical and Experimental Gastroenterology; 2012; 5: 113–121; Published online 2012 Jul 5. doi: 10.2147/CEG.S32368.
(4) Shaima Saqib, Attiya Akram, Sobia Ahsan Halim and Raazia Tassaduq; Sources of β-galactosidase and its applications in food industry; 3 Biotech. 2017 May; 7(1): 79. Published online 2017 May 12. doi: 10.1007/s13205-017-0645-5.
(6) BY DR. BRAD RACHMAN; Unique Features and Application of Non-Animal Derived Enzymes; CNI510 8/97; CLINICAL NUTRITION INSIGHTS; Copyright ® 1997 by Advanced Nutrition Publications, Inc.; Vol. 5, No. 10.
(7) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Jan 16, 2014; Last Updated: Feb 16, 2019; Betaine (trimethylglycine); Examine.com; https://examine.com/supplements/trimethylglycine/
(8) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: May 18, 2014; Last Updated: Oct 9, 2018; Bromelain; Examine.com; https://examine.com/supplements/bromelain/
(9) Xiao-Zhou Zhang and Yi-Heng Percival Zhang; CELLULASES: CHARACTERISTICS, SOURCES, PRODUCTION, AND APPLICATIONS; Bioprocessing Technologies in Biorefi nery for Sustainable Production of Fuels, Chemicals, and Polymers, First Edition. Edited by Shang-Tian Yang, Hesham A. El-Enshasy, and Nuttha Thongchul; © 2013 John Wiley & Sons, Inc. Published 2013 by John Wiley & Sons, Inc.
(10) Peter J. Butterworth Frederick J. Warren Peter R. Ellis; Human α‐amylase and starch digestion: An interesting marriage; Wiley Online Library; Starch - StärkeVolume 63, Issue 7; First published: 23 February 2011.
(11) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721508/
(12) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110206/

 

Subsegment: Tract digestiv

 

Alfa-Max®

(3) Kundan Singh Bora’ Anupam Sharma; Phytochemical and pharmacological potential pf Medicago sativa: A review; pg. 211-220; Pharmaceutical Biology; Volume 49, 2011 - Issue 2.

 

Aloe Vera Gel & Juice with Aloe PolyMax+™

(1) Amar Surjushe, Resham Vasani, and D G Saple; ALOE VERA: A SHORT REVIEW; Indian Journal of Dermatology. 2008; 53(4): 163–166; doi: 10.4103/0019-5154.44785.
(2) Lesley Braun; Marc Cohen; Herbs and Natural Supplements. An evidence-based guide, 3RD Edition; 2010; Aloe vera; pg. 192-200.

 

Charcoal Activated (Cărbune medicinal) 280 mg

(4) Jennifer Huizen; What are the benefits of activated charcoal?; Medical News Today; Last reviewed Fri 27 July 2018; https://www.medicalnewstoday.com/articles/322609.php .

 

Chlorella Micro-algae 410 mg

(5) https://examine.com/supplements/chlorella/
(6) Monograph: Chlorella - Chlorella vulgaris, Health Canada, 2018-08-28, www.hc-sc.gc.ca
(7) ALTERNATIVE & COMPLEMENTARY THERAPIEs, Chlorella and Spirulina-Green Supplements for Balancing the Body, JUNE 2001.
(8) Beth M. Ley, " Chlorella: The Ultimate Green Food : Nature's Richest Source of Chlorophyll, DNA & RNA : a Health Learning Handbook", BL Publications, 2003.

 

Chlorofresh® Capsules

(9) Kahramanmaraş Sütçü İmam University, Faculty of Agriculture, Department of Food Engineering, Kahramanmaraş, Turkey; Chlorophyll: Structural Properties, Health Benefits and Its Occurrence in Virgin Olive Oils; Akademik Gıda 9(2) (2011) 26-32; Review Paper / Derleme Makale.

 

Chlorofresh® Mint Liquid

(9) Kahramanmaraş Sütçü İmam University, Faculty of Agriculture, Department of Food Engineering, Kahramanmaraş, Turkey; Chlorophyll: Structural Properties, Health Benefits and Its Occurrence in Virgin Olive Oils; Akademik Gıda 9(2) (2011) 26-32; Review Paper / Derleme Makale.

 

Coconut Oil Extra Virgin

(10) E.V. Carandang; Health benefits of virgin oconut oil; HEALTH; January 2008; pg. 8-12.
(11) Mary G. Enig, Ph.D; Health and Nutritional Benefits from Coconut Oil: An Important Functional Food; for the 21st Century; Presented at the AVOC Lauric Oils Symposium, Ho Chi Min City, Vietnam, 25; April 1996.

 

Coconut Oil Extra Virgin 1000 mg

(10) E.V. Carandang; Health benefits of virgin oconut oil; HEALTH; January 2008; pg. 8-12.
(11) Mary G. Enig, Ph.D; Health and Nutritional Benefits from Coconut Oil: An Important Functional Food; for the 21st Century; Presented at the AVOC Lauric Oils Symposium, Ho Chi Min City, Vietnam, 25; April 1996.

 

Fennel (Fenicul) 450 mg

(12) Shamkant B. Badgujar, Vainav V. Patel, and Atmaram H. Bandivdekar; Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology; Biomed Research International. 2014; 2014: 842674; Published online 2014 Aug 3. doi: 10.1155/2014/842674.
(13) Hye Won Lee, PhD,a Hyun-Ja Lim, RN, PhD,b Ji Hee Jun, MSc,a Hyun-Suk Lim, RN, PhD,c and Myeong Soo Lee; Fennel (Foeniculum vulgare) on management of menopausal symptoms; A protocol for systematic review of randomized controlled trials; Medicine (Baltimore). 2018 Mar; 97(13): e0223; Published online 2018 Mar 30. doi: 10.1097/MD.0000000000010223.

 

Gastro Acid Support

(17) Salima T. Minzanova,1 Vladimir F. Mironov et. Al., “ Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review”, Polymers (Basel). 2018 Dec; 10(12): 1407.
(18) https://www.intechopen.com/books/stomach-disorders/the-purview-of-phytotherapy-in-the-management-of-gastric-ulcer
(19) Gerhard Meisenberg, William H. Simmons, “Principles of Medical Biochemistry”, Chapter 20: “Digestive Enzyme”, pp.334-341, January 2012. DOI: 10.1016/B978-0-323-07155-0.00019-8.
(20) Shamkant B. Badgujar, Vainav V. Patel, and Atmaram H. Bandivdekar; Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology; Biomed Research International. 2014; 2014: 842674; Published online 2014 Aug 3. doi: 10.1155/2014/842674.
(21) Lesley Braun, Marc Cohen, " Herb& Natural Supplements- An evidence-based guide", 3RD EDITION, Rosemary pg. 801- 805

 

Ginger Root

(22) Mehrnaz Nikkhah; Bodagh Iradj Maleki; Azita Hekmatdoost; Ginger in gastrointestinal disorders: A systematic review of clinical trials; Food Science & NutritionVolume 7, Issue 1.
(23) Wilson, Patrick B; Ginger (Zingiber officinale) as an Analgesic and Ergogenic Aid in Sport: A Systemic Review; Journal of Strength and Conditioning Research: October 2015 - Volume 29 - Issue 10 - p 2980–2995.
(24) Jalil Hosseini, M.D, Azar Mardi Mamaghani, M.Sc, Hani Hosseinifar, Ph.D, Mohammad Ali Sadighi Gilani, Farid Dadkhah and Mahdi Sepidarkish; The influence of ginger (Zingiber officinale) on human sperm quality and DNA fragmentation: A double-blind randomized clinical trial; International Journal of Reproductive Biomedicine (Yazd). 2016 Aug; 14(8): 533–540.
(25) Mohamad Hesam Shahrajabian, Wenli Sun & Qi Cheng; Clinical aspects and health benefits of ginger (Zingiber officinale) in both traditional Chinese medicine and modern industry; Taylor and Francis Online; Received 28 Jan 2019, Accepted 09 Apr 2019, Published online: 24 Apr 2019.

 

Mastic Gum

(26) KONSTANTINOS S. DIMAS1, PANAYOTIS PANTAZIS and RAMA RAMANUJAM; Chios Mastic Gum: A Plant-produced Resin Exhibiting Numerous Diverse Pharmaceutical and Biomedical Properties; International Journal of Experimental Clinical Pathophysyology and Drug Research; September-octomber, 2012, vol. 26, no. 5, pg. 777-785.

 

Neem Leaf

(27) Mohammad A. Alzohairy, “ Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment”, Evid Based Complement Alternat Med. 2016; 2016: 7382506.

 

Pancreas Caps™

(28) Adrian White; Medically reviewed by Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT; Should I Take Pancreatic Supplements?; October 26, 2017; Healthline.
(29) H.Nalini Sofia; Thomas M. Walter; Review of Glycyrrhiza glabra, Linn; https://www.researchgate.net/publication/36448296.
(30) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Aug 18, 2014; Last Updated: Jun 14, 2018; Taraxacum officinale; Examine.com; https://examine.com/supplements/taraxacum-officinale/#interactions-with-glucose-metabolism_absorption

 

Parasites Cleanse

(14) Silvia Cristina Cerini Trevisa; Aline Pereira Paes Menezes; Sandra Maria Barbalho; Élen Landgraf Guiguer; PROPERTIES OF MENTHA PIPERITA: A BRIEF REVIEW; WORLD JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH; www.wjpmr.com .
(31) Assessment report on Juglans regia L., folium; Based on Article 16d(1), Article 16f and Article 16h of Directive 2001/83/EC as amended (traditional use); 9 July 2013; EMA/HMPC/346740/2011; Committee on Herbal Medicinal Products (HMPC).
(32) MONIKA MITTAL, NOMITA GUPTA, PALAK PARASHAR, VARSHA MEHRA, MANISHA KHATRI; PHYTOCHEMICAL EVALUATION AND PHARMACOLOGICAL ACTIVITY OF SYZYGIUM AROMATICUM: A COMPREHENSIVE REVIEW; International Journal of Pharmacy and Pharmaceutical Sciences; ISSN- 0975-1491 Vol 6, Issue 8, 2014.
(33) J.N.N. SHARATHCHANDRA, KALPANA PLATEL, K. SRINIVASAN; DIGESTIVE ENZYMES OF RAT PANCREAS AND SMALL INTESTINE IN RESPONSE TO ORALLY ADMINISTERED MINT (MENTHA SPICATA) LEAF AND GARLIC (ALLIUM SATIVUM) OIL; Indian Journal of Pharmacology 1995; 27: 156 – 160.
(34) Ipek Suntar, Haroon Khan, Seema Patel, Rita Celano, and Luca Rastrelli; An Overview on Citrus aurantium L.: Its Functions as Food Ingredient and Therapeutic Agent; Oxidative Medicine and Cellular Longevity; Volume 2018, Article ID 7864269, 12 pages.

 

Total Cleanse™ Daily Fiber

(37) C Gupta, D Prakash, S Gupta. Appetite Suppressing Phyto Nutrients: Potential for Combating Obesity. J Nutr Health Food Eng, 2015 - researchgate.net
(38) https://www.joslin.org/info/how_does_fiber_affect_blood_glucose_levels.html
(39) SebelyPal, SimoneRadavelli-Bagatini, SuleenHo, Jenny-LeeMcKay, MonicaJane, Chapter 42 - Using Psyllium to Prevent and Treat Obesity Comorbidities, Nutrition in the Prevention and Treatment of Abdominal Obesity, 2014, Pages 505-514.
(40) https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-plantago-ovata-forskk-semen_en.pdf
(41) Amar Surjushe, Resham Vasani, and D G Saple; ALOE VERA: A SHORT REVIEW; Indian Journal of Dermatology. 2008; 53(4): 163–166; doi: 10.4103/0019-5154.44785.
(42) Canani, Roberto Berni et al. “Potential beneficial effects of butyrate in intestinal and extraintestinal diseases.” World journal of gastroenterology vol. 17,12 (2011): 1519-28.

 

Total Cleanse™ Colon

(1) Amar Surjushe, Resham Vasani, and D G Saple; ALOE VERA: A SHORT REVIEW; Indian Journal of Dermatology. 2008; 53(4): 163–166; doi: 10.4103/0019-5154.44785.
(2) Lesley Braun; Marc Cohen; Herbs and Natural Supplements. An evidence-based guide, 3RD Edition; 2010; Aloe vera; pg. 192-200.
(14) Silvia Cristina Cerini Trevisa; Aline Pereira Paes Menezes; Sandra Maria Barbalho; Élen Landgraf Guiguer; PROPERTIES OF MENTHA PIPERITA: A BRIEF REVIEW; WORLD JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH; www.wjpmr.com .
(35) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Sep 30, 2013; Last Updated: Jun 14, 2018; Senna alexandrina; Examine.com; https://examine.com/supplements/senna-alexandrina/
(36) Lesley Braun, Marc Cohen; Herbs and Natural Supplements, An evidence-based guide, 3rd Edition; 2010; Churchill Livingstone Elsevier; pg. 864-866.

 

Psyllium Husk 525 mg

(43) https://www.medicalnewstoday.com/articles/types-of-constipation
(44)https://www.mdpi.com/2072-6643/11/5/1130
(45) https://my.clevelandclinic.org/health/diseases/4108-diarrhea
(46)https://med.libretexts.org/Bookshelves/Nursing/Nursing_Pharmacology_(OpenRN)/07%3A_Gastrointestinal/7.04%3A_Antidiarrheal_Medications_and_Laxatives
(47)https://journals.lww.com/nutritiontodayonline/fulltext/2021/07000/psyllium__the_gel_forming_nonfermented_isolated.5.aspx
(48) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975494/
(49) https://www.sciencedirect.com/science/article/pii/S089990072200185X?via%3Dihub
(50) https://health.clevelandclinic.org/psyllium-husk
(51) https://www.sciencedirect.com/science/article/pii/S0002916522030076?via%3Dihub
(52) https://www.ajconline.org/article/S0002-9149(18)31332-8/fulltext
(53) https://www.sciencedirect.com/science/article/pii/S0002916523272354?via%3Dihub
(54) https://www.sciencedirect.com/science/article/pii/S0195666316301738?via%3Dihub
(55) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358997/
(56)https://www.sciencedirect.com/science/article/pii/S2405654521002201

 

Subsegment: Sănătate hepatică și biliară

 

Artichoke (Anghinare) 300 mg

(1) Yerram Raju Behara, " Pharmacological studies on artichoke leaf extract -An edible herb of Mediterranean origin", JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL SCIENCES, 2011, 11(11).

 

BroccoMax®

(2) Jae Kwang Kim and Sang Un Park2, "CURRENT POTENTIAL HEALTH BENEFITS OF SULFORAPHANE ", EXCLI Journal 2016;15:571-577 – ISSN 1611-2156.
(3) Sulforaphane Glucosinolate Monograph, Alternative Medicine Review Volume 15, Number
(4) Oh CJ, Kim JY, Min AK et. Al., " Sulforaphane attenuates hepatic fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-β/Smad signaling.", Free Radic Biol Med. 2012 Feb 1;52(3):671-682. doi: 10.1016/j.freeradbiomed.2011.11.012. Epub 2011 Dec 1.

 

Dandelion (Păpădie) 520 mg

(5)https://examine.com/supplements/taraxacum-officinale/
(6) Katrin Schütz, ReinholdCarle, Andreas Schieber, " Taraxacum—A review on its phytochemical and pharmacological profile", Institute of Food Technology, Section Plant Foodstuff Technology, Hohenheim University, https://doi.org/10.1016/j.jep.2006.07.021

 

 

Guard-Your-Liver®

(7) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316137/
(8) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565322/
(9) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562414/
(10) https://pubmed.ncbi.nlm.nih.gov/7782901/
(11) https://pubmed.ncbi.nlm.nih.gov/23295697/
(12) https://pubmed.ncbi.nlm.nih.gov/22134222/
(13) 1. https://reset.me/story/milk-thistle-a-thorn-in-the-side-of-liver-disease-cancer-diabetes-and-more/
(14) Kvasnicka F, Bíba B, Sevcík R, Voldrich M, Krátká J. Analysis of the active components of silymarin. J Chromatogr A. 2003;990:239–245.
(15) Trouillas P, Marsal P, Svobodová A, Vostálová J, Gazák R, Hrbác J, Sedmera P, Kren V, Lazzaroni R, Duroux JL, et al. Mechanism of the antioxidant action of silybin and 2,3-dehydrosilybin flavonolignans: a joint experimental and theoretical study. J Phys Chem A. 2008;112:1054–1063.
(16) Nomura M, Takahashi T, Nagata N, Tsutsumi K, Kobayashi S, Akiba T, Yokogawa K, Moritani S, Miyamoto K. Inhibitory mechanisms of flavonoids on insulin-stimulated glucose uptake in MC3T3-G2/PA6 adipose cells. Biol Pharm Bull. 2008;31:1403–1409.
(17) Detaille D, Sanchez C, Sanz N, Lopez-Novoa JM, Leverve X, El-Mir MY. Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes. Life Sci. 2008;82:1070–1076.
(18) Arcari, M.; Brambilla, A.; Brandt, A.; Caponi, R.; Corsi, G.; Di, R.M.; Solinas, F.; Wachter, W.P. A new inclusion complex of silibinin and beta-cyclodextrins: In vitro dissolution kinetics and in vivo absorption in comparison with traditional formulations. Boll. Chim. Farm. 1992, 131, 205–209.

 

Glutathione Reduced 500 mg

(19) Vivek Kumar Bains, Rhythm Bains, " The antioxidant master glutathione and periodontal health", Dent Res J (Isfahan). 2015 Sep-Oct; 12(5): 389–405.
(20) Guoyao Wu, Yun-Zhong Fang et. Al., " Glutathione Metabolism and Its Implications for Health", The Journal of Nutrition, Volume 134, Issue 3, March 2004, Pages 489–492.
(21) Lien Ai Pham-Huy, Hua He et. Al., " Free Radicals, Antioxidants in Disease and Health", Int J Biomed Sci. 2008 Jun; 4(2): 89–96.
(22) Volodymyr I. Lushchak, " Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions", Journal of Amino Acids, Volume 2012, Article ID 736837.

 

Kudzu

(23) WeiliZhu, YinanZhang et. Al., "Chapter Twelve - Chinese Herbal Medicine for the Treatment of Drug Addiction", International Review of Neurobiology, Volume 135, 2017, Pages 279-295.
(24) Guerra MC, Speroni E, Broccoli M et. Al., " Comparison between chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin antioxidant properties and effects on rat liver CYP-catalysed drug metabolism.", Life Sci. 2000 Nov 3;67(24):2997-3006.

 

L-Arginine 1000mg

(25) H Tapieroa, G Mathé, P Couvreur, K.D Tew, " I. Arginine", Biomedicine & Pharmacotherapy Volume 56, Issue 9, November 2002, Pages 439-445.
(26) Yvonne L. J. Vissers, Iris B. J. G. Debats et. Al., " Pros and cons of L-arginine supplementation in disease", Nutrition Research Reviews (2004), 17, 193–210.
(27) Guoyao Wu, Fuller W. Bazer, " Arginine metabolism and nutrition in growth, health and disease", Amino Acids, May 2009, Volume 37, Issue 1, pp 153–168.

 

Liver Blend SP-13

(1) Yerram Raju Behara, " Pharmacological studies on artichoke leaf extract -An edible herb of Mediterranean origin", JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL SCIENCES, 2011, 11(11).

 

 

Milk Thistle Phytosome

(28) Phytosomes: The New Technology for Enhancement of Bioavailability of Botanicals and Nutraceuticals, International Journal of Health Research, September 2009; 2(3): 225-232.
(29) Gholamreza Karimi, Maryam Vahabzadeh et. Al., " “Silymarin”, a Promising Pharmacological Agent for Treatment of Diseases", Iran J Basic Med Sci. 2011 Jul-Aug; 14(4): 308–317.
(30) Peter F. Surai, " Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives", Antioxidants (Basel). 2015 Mar; 4(1): 204–247.
(31) Conf. Dr. Cerasela Elena Gîrd, " Curs de Farmacognozie, Fitochimie, Fitoterapie", Vol. 1, pg. 150, Editura Curtea Veche, 2010.
(32) Alan F Hofmann, " Biliary secretion and excretion in health and disease: Current concepts", AF Hofmann. Biliary secretion and excretion in health and disease: Current Concepts", Annals of Hepatology, 2007; 6(1): January-March: 15-27.

 

SAM-e 200 mg

(33) Teodoro Bottiglieri, " S-Adenosyl-L-methionine (SAMe): from the bench to the bedside—molecular basis of a pleiotrophic molecule", The American Journal of Clinical Nutrition, Volume 76, Issue 5, November 2002, Pages 1151S–1157S, https://doi.org/10.1093/ajcn/76.5.1151S.
(34) Sarah E. Montgomery, Amir A. Sepehry, " The Effect of S-Adenosylmethionine on Cognitive Performance in Mice: An Animal Model Meta-Analysis", PLoS One. 2014; 9(10): e107756.
(35) Gregory S. Kelly, N.D., " Sports Nutrition: Selected Nutritional Supplements For Bodybuilders and Strength Athletes", Alternative Medicine Review, Volume 2, /number 3, 1997.
(36) https://examine.com/supplements/s-adenosyl-methionine/

 

Schisandra 580 mg

(37) Research analysis led by Kamal Patel; All content reviewed by the Examine.com Team. Published: Aug 18, 2014; Last Updated: Jun 14, 2018; Taraxacum officinale; Examine.com; https://examine.com/supplements/taraxacum-officinale/#interactions-with-glucose-metabolism_absorption
(38) Assessment report on Juglans regia L., folium; Based on Article 16d(1), Article 16f and Article 16h of Directive 2001/83/EC as amended (traditional use); 9 July 2013; EMA/HMPC/346740/2011; Committee on Herbal Medicinal Products (HMPC).
(39) MONIKA MITTAL, NOMITA GUPTA, PALAK PARASHAR, VARSHA MEHRA, MANISHA KHATRI; PHYTOCHEMICAL EVALUATION AND PHARMACOLOGICAL ACTIVITY OF SYZYGIUM AROMATICUM: A COMPREHENSIVE REVIEW; International Journal of Pharmacy and Pharmaceutical Sciences; ISSN- 0975-1491 Vol 6, Issue 8, 2014.
(40) J.N.N. SHARATHCHANDRA, KALPANA PLATEL, K. SRINIVASAN; DIGESTIVE ENZYMES OF RAT PANCREAS AND SMALL INTESTINE IN RESPONSE TO ORALLY ADMINISTERED MINT (MENTHA SPICATA) LEAF AND GARLIC (ALLIUM SATIVUM) OIL; Indian Journal of Pharmacology 1995; 27: 156 – 160.

 

Total Cleanse™ Liver

(41) Gholamreza Karimi, Maryam Vahabzadeh et. Al., " “Silymarin”, a Promising Pharmacological Agent for Treatment of Diseases", Iran J Basic Med Sci. 2011 Jul-Aug; 14(4): 308–317.
(42) Cerasela Elena Gîrd, " Curs de Farmacognozie, Fitochimie, Fitoterapie", Vol. 2, 2010, pg. 52-53.
(43) Dr. Radu Ciprian Țincu, " Studiu retrospectiv privind efectul preparatului Total Cleanse™ Liver în intoxicația cu mercur", secția ATI-Toxicologie, Spitalu Clinic de Urgență București.
(44) Volodymyr I. Lushchak, " Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions", Journal of Amino Acids, Volume 2012, Article ID 736837, 26 pages.

 

S-Acetyl L-Glutathione 100 mg

(19) Vivek Kumar Bains, Rhythm Bains, " The antioxidant master glutathione and periodontal health", Dent Res J (Isfahan). 2015 Sep-Oct; 12(5): 389–405.
(20) Guoyao Wu, Yun-Zhong Fang et. Al., " Glutathione Metabolism and Its Implications for Health", The Journal of Nutrition, Volume 134, Issue 3, March 2004, Pages 489–492.
(21) Lien Ai Pham-Huy, Hua He et. Al., " Free Radicals, Antioxidants in Disease and Health", Int J Biomed Sci. 2008 Jun; 4(2): 89–96.
(45) https://pubmed.ncbi.nlm.nih.gov/22504020/
(46) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997318/
(47) https://www.mdpi.com/2072-6643/11/9/2073
(48) https://www.differencebetween.com/what-is-the-difference-between-l-glutathione-and-s-acetyl-glutathione/
(49) https://www.mdpi.com/2076-3921/12/5/10944
(50) https://jarrow.com/products/s-acetyl-l-glutathione-100-mg-60-tablets?_pos=1&_sid=9c3c0494e&_ss=r
(51) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024626/
(52) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746815/
(53) https://www.carolinasthyroidinstitute.com/glutathione-a-power-tool-in-hashimotos-management/
(54) https://insights.tessmed.com/does-glutathione-help-thyroid-health-taking-a-closer-look-at-the-possibilities-of-supplementation/
(55) https://pubmed.ncbi.nlm.nih.gov/11743644/
(56) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991679/
(57) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844662/
(58) https://www.invigormedical.com/anti-aging/understanding-glutathione-deficiency-symptoms-causes-treatment/
(59) https://dochospitals.com/en/glutathione-atc117/
(60) https://www.researchgate.net/publication/331475848_Oral_Administration_of_S-acetyl-glutathione_Impact_on_the_Levels_of_Glutathione_in_Plasma_and_in_Erythrocytes_of_Healthy_Volunteers
(61) https://link.springer.com/article/10.1186/2046-0481-65-4
(62) https://www.sciencedirect.com/science/article/abs/pii/S1382668914001434
(63) https://link.springer.com/chapter/10.1007/978-1-4614-6093-0_1
(64) https://link.springer.com/article/10.1007/s10522-010-9282-7
(65) https://www.sciencedirect.com/science/article/abs/pii/S0891584907000494
(66) https://www.spandidos-publications.com/10.3892/ol.2012.931#b13-ol-04-06-1247
(67) https://www.tandfonline.com/doi/full/10.1080/1828051X.2023.2221073
(68) https://doi.org/10.1111/j.1749-6632.1998.tb09905.x
(69) https://www.sciencedirect.com/science/article/abs/pii/S030100829900060X?via%3Dihub
(70) https://doi.org/10.1073/pnas.1817885116
(71) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684116/
(72) https://journals.physiology.org/doi/full/10.1152/ajplung.1998.275.1.L80
(73) https://link.springer.com/article/10.1023/A:1023858902184
(74) https://www.ingentaconnect.com/content/ben/mroc/2013/00000010/00000004/art00002
(75) https://rjid.com.ro/articles/2008.2/RJID_2008_2_Art-04.pdf

 

Par, piele, unghii

 

Astaxanthin 12 mg

(8) Lawson Ekpe, Kenneth Inaku, Victor Ekpe, Antioxidant effects of astaxanthin in various diseases—a review, JOURNAL OF MOLECULAR PATHOPHYSIOLOGY, 2018 VOL 7, NO. 1, PAGE 1–6 10.5455/jmp.20180627120817.
(9) Annil Mahajan, Vishal R Tandon, ANTIOXIDANTS AND RHEUMATOID ARTHRITIS, J Indian Rheumatol Assoc 2004 : 12 : 139 - 142.
(10) Choi SK, Park YS, Choi DK, Chang HI, Effects of astaxanthin on the production of NO and the expression of COX-2 and iNOS in LPS-stimulated BV2 microglial cells, J Microbiol Biotechnol. 2008 Dec;18(12):1990-6.
(11)https://supplementsinreview.com/vision/astaxanthin-vision/#protecting-the-retina-via-antioxidation
(12) Kindlund, P.J. Nutrafoods (2011) 10: 49. https://doi.org/10.1007/BF0322338.
(13) Ranga Rao Ambati, Siew Moi Phang, Sarada Ravi, Ravishankar Gokare Aswathanarayana, Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review, Mar. Drugs 2014, 12, 128-152;
(14) Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. (2011).
(15) Tominaga K, Hongo N, Karato M, Yamashita E, Cosmetic benefits of astaxanthin on humans subjects, Acta Biochim Pol. 2012;59(1):43-7. Epub 2012 Mar 17.

 

Bamboo

(10) https://siliciumg5.com/blog/en/benefits-of-silica/
(11) https://www.healthaid.co.uk/blogs/news/health-benefits-silica
(9) Lela Munjas Jurkić ,Ivica Cepanec ,Sandra Kraljević Pavelić &Krešimir Pavelić, “ Biological and therapeutic effects of ortho-silicic acid and some ortho-silicic acid-releasing compounds: New perspectives for therapy”, Nutrition & Metabolism volume 10, Article number: 2 (2013).

 

Biotin 1000mcg

(12) https://www.medicalnewstoday.com/articles/318724
(13) https://www.medicalnewstoday.com/articles/287720#benefits
(14) https://lpi.oregonstate.edu/mic/vitamins/biotin
(15) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386534/
(16) https://www.ncbi.nlm.nih.gov/books/NBK547751/
(17) https://www.sciencedirect.com/science/article/abs/pii/S0006899322002554
(18) https://www.tandfonline.com/doi/full/10.1080/09546634.2017.1395799

 

Burdock (Brusture) 425 mg

(19)https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-arctium-lappa-l-radix_en.pdf
(20) https://www.livestrong.com/article/322548-supplements-to-improve-lymphatic-drainage/

 

Famil E®

(21) https://www.naturalproductsinsider.com/heart-health/many-forms-vitamin-e

(22) https://www.webmd.com/diet/supplement-guide-vitamin-e#1

(23)  https://www.naturalproductsinsider.com/heart-health/many-forms-vitamin-e

 

Florasone® Eczema Cream

(24) Roberta Gaziano, Elena Campione, Federico Iacovelli, Daniele Marino, Francesca Pica, Paolo Di Francesco, Stefano Aquaro, Francesco Menichini, Mattia Falconi, and Luca Bianchi; Antifungal activity of Cardiospermum halicacabum L. (Sapindaceae) against Trichophyton rubrum occurs through molecular interaction with fungal Hsp90; Drug Des Devel Ther. 2018; 12: 2185–2193.
(25) Ashish S. Zalke, B. Duraiswamy, Upendra B. Gandagule, and Nidhi Singh; Pharmacognostical evaluation of Cardiospermum halicacabum Linn. leaf and stem; Anc Sci Life. 2013 Jul-Sep; 33(1): 15–21.
(26) DANILO CARLONI; Cardiospermum halicacabum for the treatment of dermatitis Cardiospermum halicacabum, Sapindaceae family: a plant with a cortison-like action as a valid alternative to traditional dermatological applications; FITOTHERAPY APPLICATIONS.

 

Food Carotene™ 25000 UI

(27) Burri, B. J. (1997). Beta-carotene and human health: A review of current research. Nutrition Research, 17(3), 547–580.

(28) https://www.webmd.com/vitamins/ai/ingredientmono-964/vitamin-a

 

Hair-Nutrition

(29) https://pubmed.ncbi.nlm.nih.gov/25386609/
(30) https://www.oxfordbiolabs.com/blogs/news/amino-acid-supplements-benefits-hair
(31) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380979/
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Mangosteen 500 mg

(50) Jordan S. Pober and William C. Sessa; Inflammation and the Blood Microvascular System; Cold Spring Harb Perspect Biol. 2015 Jan; 7(1): a016345.
(51) Anthony C; A review of Mangosteen (Garcinia mangostana) Linn; Dweck Data.
(52) Fabiola Gutierrez-Orozco and Mark L. Failla, Biological Activities and Bioavailability of Mangosteen Xanthones: A Critical Review of the Current Evidence; Nutrients. 2013 Aug; 5(8): 3163–3183.

 

Psoriaflora® Psoriasis Cream

(53) Monica Janeczek, Lauren Moy et. al., " Review of the Efficacy and Safety of Topical Mahonia aquifolium for the Treatment of Psoriasis and Atopic Dermatitis", J Clin Aesthet Dermatol. 2018 Dec; 11(12): 42–47.

 

Skin Blend SP-4™

(54) Salama M. El-Darier and Shaimaa G. Salama, " Arctium Lappa L. (Asteraceae); a New Invasive Highly Specific Medicinal Plant Growing in Egypt", Pyrex Journal of Plant and Agricultural Research, Vol 2 (2) pp. 44-53 September, 2016.

(55) Clara Circosta, Rita De Pasquale et. Al., " Effects of isoflavones from red clover (Trifolium pratense) on skin changes induced by ovariectomy in rats", Phytotherapy Research, 01 November 2006.

 

Super Tremella

(56)https://www.mushroomnutrition.com/tremella-fuciformis

(57) Yu-ji Wu, Zheng-xun Wei et. Al., " Structure, bioactivities and applications of the polysaccharides from Tremella fuciformis mushroom: A review", International Journal of Biological Macromolecules, Volume 121, January 2019, Pages 1005-1010.

 

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