Surse cod QR Brosura Good Routine Kids

Immuno-Complex

https://www.mdpi.com/2072-6643/11/8/1925
Effects of Lactobacillus plantarum and Lactobacillus paracasei on the Peripheral Immune Response in Children with Celiac Disease Autoimmunity: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
https://www.mdpi.com/2673-8449/1/2/6
Involvement of Probiotics and Postbiotics in the Immune System
https://www.metagenicsinstitute.com.au/tech-data/Lactobacillus-plantarum-lactobacillus-paracasei-
Lactobacillus paracasei (LP-33®) and Lactobacillus rhamnosus (LGG®) for Immune Control
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000506/
Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, double-blind, placebo-controlled clinical study
https://www.mdpi.com/1422-0067/23/17/9784
An Update on the Effects of Vitamin D on the Immune System and Autoimmune Diseases
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313088/
The Impact of Zinc and Zinc Homeostasis on the Intestinal Mucosal Barrier and Intestinal Diseases
https://pubmed.ncbi.nlm.nih.gov/20803023/
Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284493/
Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials
https://www.mdpi.com/2072-6643/9/11/1211
Vitamin C and Immune Function
https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
Vitamin C and Health
https://pmc.ncbi.nlm.nih.gov/articles/PMC2821804/
The vitamin D–antimicrobial peptide pathway and its role in protection against infection
https://www.medicover.ro/analize/imunoglobulina-a-iga-totala/
Imunoglobulina A (IgA) totala
sciencedirect.com/science/article/abs/pii/S019697811930155X
Inducible expression of defensins and cathelicidins by nutrients and associated regulatory mechanisms

https://journals.physiology.org/doi/full/10.1152/ajpgi.00327.2009
Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier

Baby-Colic

https://www.mdpi.com/2076-2607/10/2/278
Why Are Bifidobacteria Important for Infants?
https://gateway.euro.who.int/en/indicators/hfa_596-7060-caesarean-sections-per-1000-live-births/#id…
Caesarean sections per 1000 live births
https://data.unicef.org/topic/nutrition/infant-and-young-child-feeding/
Infant and young child feeding
https://www.who.int/publications/i/item/9789241514880
WHO report on surveillance of antibiotic consumption: 2016-2018 early implementation
https://www.wageningenacademic.com/doi/10.3920/BM2020.0233
Efficacy of Bifidobacterium animalis subsp. lactis, BB-12® on infant colic – a randomised, double-blinded, placebo-controlled study
https://pubmed.ncbi.nlm.nih.gov/26756877/
Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Children
https://pubmed.ncbi.nlm.nih.gov/37764787/
Seeding the Infant Gut in Early Life-Effects of Maternal and Infant Seeding with Probiotics on Strain Transfer, Microbiota, and Gastrointestinal Symptoms in Healthy Breastfed Infants
https://www.mdpi.com/2072-6643/16/7/1002
Prebiotic Strategies to Manage Lactose Intolerance Symptoms
https://pubmed.ncbi.nlm.nih.gov/34550055/
Efficacy of Bifidobacterium animalis subsp. lactis, BB-12® on infant colic - a randomised, double-blinded, placebo-controlled study
https://www.researchgate.net/publication/353355890_Immunomodulation_by_Bifidobacterium_animalis_sub…
Immunomodulation by Bifidobacterium animalis subsp. lactis Bb12: Integrative Analysis of miRNA Expression and TLR2 Pathway–Related Target Proteins in Swine Monocytes
https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/probiotics-ben…
Probiotics: beneficial factors of the defence system
https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/human-studies-with-pro…
Human studies with probiotics and prebiotics: clinical implications
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457741/
Development of Gut Microbiota in the First 1000 Days after Birth and Potential Interventions

https://www.sciencedirect.com/science/article/pii/S0966842X1830204X
The Human Microbiome and Child Growth – First 1000 Days and Beyond
https://www.annallergy.org/article/S1081-1206(24)00152-2/fulltext
Gut microbiome in the first 1000 days and risk for childhood food allergy
https://www.researchgate.net/publication/362973400_The_First_1000_Days_Assembly_of_the_Neonatal_Mic…
The First 1000 Days: Assembly of the Neonatal Microbiome and Its Impact on Health Outcomes
https://www.sciencedirect.com/science/article/abs/pii/S1081120624001522?dgcid=rss_sd_all
Gut microbiome in the first 1000 days and risk for childhood food allergy
https://www.novonesis.com/en/biosolutions/human-health/b-lactis-bb-12

Why Are Bifidobacteria Important for Infants? | MDPI

Flora-Balance Jr.

https://clasado.com/science/
Introducing Bimuno
https://www.tandfonline.com/doi/full/10.1080/19490976.2020.1826747#abstract
Influence of probiotic supplementation on the developing microbiota in human preterm neonates
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681247/
A Double Blind, Randomized, Placebo-Controlled Trial of Lactobacillus acidophilus for the Treatment of Acute Watery Diarrhea in Vietnamese Children
https://hcp.howaru.com/strains/la-14/
La-14® introduction
https://www.saeka.si/wp-content/uploads/2020/04/La-14-TM.pdf
Lactobacillus acidophilus – characteristics of the genus, safe for consumption, applications and stabilty, benefit summary
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012958/
Efficacy of Bifidobacterium longum alone or in multi-strain probiotic formulations during early life and beyond
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844131/
Lactobacillus rhamnosus GG Intake Modifies Preschool Children’s Intestinal Microbiota, Alleviates Penicillin-Associated Changes, and Reduces Antibiotic Use
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851694/
Prebiotics, Bone and Mineral Metabolism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657340/
Persistence of the Probiotic Lacticaseibacillus rhamnosus Strain GG (LGG) in an In Vitro Model of the Gut Microbiome
https://www.optibacprobiotics.com/professionals/probiotics-database/lactobacillus/lactobacillus-rha…
Lactobacillus rhamnosus GG – Safety and Survival, upper respiratory tract infections, IBS, ow’s Milk Protein Allergy, Gastroenteritis
https://www.transparentlabs.com/blogs/all/guide-to-the-best-probiotics-for-gut-health-strains-backe…
Guide to the Best Probiotics for Gut Health: Strains that Are Backed by Science.
https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-023-05324-4
Assessment of probiotic strain Lactobacillus acidophilus LB supplementation as adjunctive management of attention-deficit hyperactivity disorder in children and adolescents: a randomized controlled clinical trial
https://www.sciencedirect.com/science/article/pii/S0149763421002748
The effect of probiotics on cognitive function across the human lifespan: A systematic review
https://www.mdpi.com/2076-2607/11/3/636
Lactobacilli and Their Probiotic Effects in the Vagina of Reproductive Age Women
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306308/
Lactobacillus rhamnosus GG and butyrate supplementation in rats with bone cancer reduces mechanical allodynia and increases expression of μ-opioid receptor in the spinal cord
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045382/
Beneficial Effects of Viable and Heat-Inactivated Lactobacillus rhamnosus GG Administration on Oxidative Stress and Inflammation in Diet-Induced NAFLD in Rats
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472411/
Probiotic Supplementation and Micronutrient Status in Healthy Subjects: A Systematic Review of Clinical Trials
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239510/
Ehealth: Low FODMAP diet vs Lactobacillus rhamnosus GG in irritable bowel syndrome
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156670/
Development of gut microbiota during the first 2 years of life
care4-U.com I howaru.com, July 2024
Probiotics essential - Bifidobacterium breve Bb-18™
https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/probiotics-ben…
Probiotics: beneficial factors of the defence system
https://www.mdpi.com/2072-6643/13/9/3061
Irritable Bowel Syndrome, Depression, and Neurodegeneration: A Bidirectional Communication from Gut to Brain
https://www.researchgate.net/figure/WHO-recommended-tiered-set-of-early-life-age-groups_tbl4_257529…

Hydra-Boost Jr.

https://www.ncbi.nlm.nih.gov/books/NBK231364/ Use of Carbohydrate-Electrolyte Solutions for Fluid Replacement
https://pmc.ncbi.nlm.nih.gov/articles/PMC4850308/ The Sodium Glucose Cotransporter SGLT1 Is an Extremely Efficient Facilitator of Passive Water Transport (2016)
https://link.springer.com/article/10.1007/s11894-019-0734-1 Principles and Practice of Oral Rehydration (2019)
https://www.sciencedirect.com/topics/chemistry/sodium-citrate Sodium Citrate (2007)
https://www.revistanutricion.org/articles/an-overview-on-electrolytes-its-importance-function-and-i… An overview on electrolytes: Its importance, function, and imbalances (2023)
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/sodium-chlo… Sodium Chloride
https://pmc.ncbi.nlm.nih.gov/articles/PMC7378437/ Sodium–glucose cotransporters: Functional properties and pharmaceutical potential 2020)
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https://www.idsociety.org/practice-guideline/infectious-diarrhea/
IDSA 2017 Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea (2017)
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https://www.who.int/news-room/fact-sheets/detail/diarrhoeal-disease
https://bjsm.bmj.com/content/bjsports/49/22/1432.full.pdf? Statement of the 3rd International Exercise-Associated Hyponatremia Consensus, Development Conference, Carlsbad, California, 2015

Synergize-Your-Gut®

https://www.mayoclinic.org/drugs-supplements-acidophilus/art-20361967
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Douillard FP, Ribbera A, Kant R, et al. Comparative genomic and functional analysis of 100 Lactobacillus rhamnosus strains and their comparison with strain GG. PLoS Genet. 2013;9(8):e1003683. doi:10.1371/journal.pgen.1003683
Ruszczyński M, Radzikowski A, Szajewska H. Clinical trial: effectiveness of Lactobacillus rhamnosus (strains E/N, Oxy and Pen) in the prevention of antibiotic-associated diarrhoea in children. Aliment Pharmacol Ther. 2008;28(1):154-161. doi:10.1111/j.1365-2036.2008.03714.x
Hill D, Sugrue I, Tobin C, Hill C, Stanton C, Ross RP. The Lactobacillus casei Group: History and Health Related Applications. Front Microbiol. 2018;9:2107. Published 2018 Sep 10. doi:10.3389/fmicb.2018.02107

Cai H, Thompson R, Budinich MF, Broadbent JR, Steele JL. Genome sequence and comparative genome analysis of Lactobacillus casei: insights into their niche-associated evolution. Genome Biol Evol. 2009;1:239-257. Published 2009 Jul 14. doi:10.1093/gbe/evp019
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Badet C, Thebaud NB. Ecology of lactobacilli in the oral cavity: a review of literature. Open Microbiol J. 2008;2:38-48. doi:10.2174/1874285800802010038
Kurt Selle, Todd R. Klaenhammer, Genomic and phenotypic evidence for probiotic influences of Lactobacillus gasseri on human health, FEMS Microbiology Reviews, Volume 37, Issue 6, November 2013, Pages 915–935, https://doi.org/10.1111/1574-6976.12021
Stoeker L, Nordone S, Gunderson S, et al. Assessment of Lactobacillus gasseri as a candidate oral vaccine vector. Clinical and Vaccine Immunology : CVI. 2011 Nov;18(11):1834-1844. DOI: 10.1128/cvi.05277-11.

Chyn Boon Wong, Toshitaka Odamaki, Jin-zhong Xiao, Insights into the reason of Human-Residential Bifidobacteria (HRB) being the natural inhabitants of the human gut and their potential health-promoting benefits, FEMS Microbiology Reviews, Volume 44, Issue 3, May 2020, Pages 369–385, https://doi.org/10.1093/femsre/fuaa010
Corrêa NB, Péret Filho LA, Penna FJ, Lima FM, Nicoli JR. A randomized formula controlled trial of Bifidobacterium lactis and Streptococcus thermophilus for prevention of antibiotic-associated diarrhea in infants. J Clin Gastroenterol. 2005;39(5):385-389. doi:10.1097/01.mcg.0000159217.47419.5b
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Muhammad Shoaiba, Aamir Shehzada, et. Al., Inulin: Properties, health benefits and food applications, Carbohydrate Polymers, Volume 147, 20 August 2016, Pages 444-454
Cukrowska B, Bierła JB, Zakrzewska M, Klukowski M, Maciorkowska E. The Relationship between the Infant Gut Microbiota and Allergy. The Role of Bifidobacterium breve and Prebiotic Oligosaccharides in the Activation of Anti-Allergic Mechanisms in Early Life. Nutrients. 2020;12(4):946. Published 2020 Mar 29 doi:10.3390/nu12040946
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https://www.mdpi.com/2673-8449/1/2/6

https://sci-hub.ru/https://doi.org/10.1111/j.1440-1754.2007.01076.x
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https://jamanetwork.com/journals/jama/fullarticle/1151505
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https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/probiotics-ben…
https://link.springer.com/article/10.1007/s00240-010-0262-9

https://pmc.ncbi.nlm.nih.gov/articles/PMC10217264/
The Effect of Probiotic Supplementation on the Gut–Brain Axis in Psychiatric Patients (2023)
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https://www.sciencedirect.com/science/article/pii/S1043661824004869 Lactobacillus rhamnosus: An emerging probiotic with therapeutic potential for depression (2025)
https://pmc.ncbi.nlm.nih.gov/articles/PMC3388628/ Effects of probiotics on serum levels of Th1/Th2 cytokine and clinical outcomes in severe traumatic brain-injured patients: a prospective randomized pilot study 2011)
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https://pmc.ncbi.nlm.nih.gov/articles/PMC9194447/ The Beneficial Role of Probiotic Lactobacillus in Respiratory Diseases (2022)
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268081/ – Probiotics, Prebiotics and Epithelial Tight Junctions: A Promising Approach (2021)
https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2023.1118529/full – Communication of Gut Microbiota and Brain via Immune & Neuroendocrine Signaling (2023)
https://pubmed.ncbi.nlm.nih.gov/38742994/ Supplementation with a Probiotic Formula Having β-Glucuronidase Activity Modulates Serum Estrogen Levels in Healthy Peri- and Postmenopausal Women (2024)
https://pmc.ncbi.nlm.nih.gov/articles/PMC10913090/ Multispecies probiotics complex improves bile acids and gut microbiota metabolism status in an in vitro fermentation model (2024)
https://www.sciencedirect.com/science/article/pii/S2665927125001698 Probiotics as a therapeutic strategy for metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis (2025)
https://pmc.ncbi.nlm.nih.gov/articles/PMC8896082/ The effects of the probiotic cocktail on modulation of the NF-kB and JAK/STAT signaling pathways involved in the inflammatory response in bowel disease model (2022)
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https://pmc.ncbi.nlm.nih.gov/articles/PMC7230973/ The Effect of Probiotics on the Production of Short-Chain Fatty Acids by Human Intestinal Microbiome (2020)
https://pmc.ncbi.nlm.nih.gov/articles/PMC9019120/ Lactobacillus spp. for Gastrointestinal Health: Current and Future Perspectives (2022)
https://pmc.ncbi.nlm.nih.gov/articles/PMC5423028/ Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria (2017)
https://pmc.ncbi.nlm.nih.gov/articles/PMC11172883/ Effects of Probiotics on Gut Microbiota: An Overview (2024)
L. salivarius, L. acidophilus, B. longum, B bifidum, L. gasseri, L. plantarum, L. lactis

Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria

Microbial Cell Factories - The aim of this review is to summarize the effect in host energy metabolism of the production of B group vitamins and short chain fatty acids (SCFA) by commensal,...

https://pmc.ncbi.nlm.nih.gov/articles/PMC9159302/ The Probiotic Lactobacillus paracasei Ameliorates Diarrhea Cause by Escherichia coli O8 via Gut Microbiota Modulation (2022)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6520754/ Effects of Bifidobacterium longum and Lactobacillus rhamnosus on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study (2019)
https://www.sciencedirect.com/science/article/pii/S1521691824000763 The role of microbiome in the development of gluten-related disorders (2024)
https://pmc.ncbi.nlm.nih.gov/articles/PMC9818925/ Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health (2023)
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Detection of Bifidobacterium Strains that Induce Large Quantities of IgA (2009)
https://www.sciencedirect.com/science/article/pii/S1323893015308789 Lactobacillus Acidophilus Strain L-92 Regulates the Production of Th1 Cytokine as well as Th2 Cytokines (2007)
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https://www.mdpi.com/2673-8007/5/1/16 Elucidating the Capacity and Mechanism of Lactiplantibacillus plantarum in Synthesizing Essential Amino Acids from Non-Essential Amino Acids in a Novel Severely Deficient Medium
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Enzy-Balance Jr.

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Effect of exogenous phytase added to small-quantity lipid-based nutrient supplements (SQ-LNS) on the fractional and total absorption of zinc from a millet-based porridge consumed with SQ-LNS in young Gambian children: a randomized controlled trial - PubMed

Oral lactase for infantile colic: a randomized double-blind placebo-controlled trial - PubMed

Digestive Enzyme Supplementation in Gastrointestinal Diseases - PMC

Safety evaluation of the food enzyme α‐amylase from the genetically modified Bacillus licheniformis strain NZYM‐BC

(https://www.efsa.europa.eu/en/efsajournal/pub/5630

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Motion-Ease

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https://www.sciencedirect.com/science/article/abs/pii/S0367326X1000239

https://www.spandidos-publications.com/10.3892/mmr.2010.377/download?
https://www.natsci.upit.ro/media/2371/34borozan-et-al.pdf
https://www.medlink.com/articles/motion-sickness

Pure-Omega 3 Jr.

https://concordix.com/our-ingredients/
Concordix - Selected Ingredients
https://goedomega3.com/index.php/members/member/vitux-as-concordix
Higher bio-availability ConCordix Soft Chews vs soft gels
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738999/
The Relationship of Docosahexaenoic Acid (DHA) with Learning and Behavior in Healthy Children: A Review
https://www.sciencedirect.com/science/article/pii/S2161831322009620
Omega-3 Fatty Acids EPA and DHA: Health Benefits Throughout Life
https://pubmed.ncbi.nlm.nih.gov/37589276/
A systematic review and meta-analysis of the omega-3 fatty acids effects on brain-derived neurotrophic factor (BDNF)
https://pubmed.ncbi.nlm.nih.gov/37329381/
Omega-3 Polyunsaturated Fatty Acids Protect Neurological Function After Traumatic Brain Injury by Suppressing Microglial Transformation to the Proinflammatory Phenotype and Activating Exosomal NGF/TrkA Signaling
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945585/
Resolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563911/
N-3 (OMEGA-3) FATTY ACIDS: EFFECTS ON BRAIN DOPAMINE SYSTEMS AND POTENTIAL ROLE IN THE ETIOLOGY AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262633/
Omega-3 long-chain polyunsaturated fatty acid and sleep: a systematic review and meta-analysis of randomized controlled trials and longitudinal studies
https://pubmed.ncbi.nlm.nih.gov/21961774/
Omega-3 fatty acid supplementation for the treatment of children with attention-deficit/hyperactivity disorder symptomatology: systematic review and meta-analysis
https://pubmed.ncbi.nlm.nih.gov/34328397/
The effect of omega-3 fatty acid supplementation on seizure frequency in individuals with epilepsy: a systematic review and meta-analysis
https://pubmed.ncbi.nlm.nih.gov/33599431/
The effect of omega-3 fatty acids supplementation on social and behavioral disorders of children with autism: a randomized clinical trial
https://www.ocl-journal.org/articles/ocl/full_html/2023/01/ocl220025/ocl220025.html
DHA (omega-3 fatty acid) and estradiol: key roles in regional cerebral glucose uptake
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347303/
Omega-3 for nonalcoholic fatty liver disease in children
https://www.regalsalmon.com/us/blog/healthy-fats-spotlight-on-omega-3-fatty-acids-by-emily-hope/
Healthy Fats & Omega-3 Fatty Acids By Emily Hope
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963309/
Safety Assessment of Docosahexaenoic Acid in X-Linked Retinitis Pigmentosa: The 4-Year DHAX Trial
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746967/
Potential Role of Omega-3 Polyunsaturated Fatty Acids in Pediatric Food Allergy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700845/
Inflammatory bowel disease: can omega-3 fatty acids really help?
https://www.sciencedirect.com/science/article/pii/S1323893014000100
Role of omega-3 fatty acids and their metabolites in asthma and allergic diseases
https://www.sciencedirect.com/science/article/pii/S0924224423001346
Benefits of supplementation with microbial omega-3 fatty acids on human health and the current market scenario for fish-free omega-3 fatty acid
https://www.massgeneral.org/children/autism/lurie-center/omega3-fatty-acids
Lurie Center for Autism: Omega-3 Fatty Acids
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060648/
Vitamin D in pediatric age: Current evidence, recommendations, and misunderstandings

Our ingredients and flavors

Calm-Blend

Clinical Efficacy and Tolerability of Lemon Balm (Melissa officinalis L.) in Psychological Well-Being: A Review (2024)
https://pmc.ncbi.nlm.nih.gov/articles/PMC11510126/
Anxiety Disorders Among Children and Adolescents (2015)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6524434/
Myo-inositol for Comorbid Anxiety in Children and Adolescents With Bipolar Disorder: Promise and Pitfalls (2013)
https://pmc.ncbi.nlm.nih.gov/articles/PMC3875047/
Rosmarinic Acid, a Bioactive Phenolic Compound, Inhibits Glutamate Release from Rat Cerebrocortical Synaptosomes through GABAA Receptor Activation (2021)
https://www.mdpi.com/2218-273X/11/7/1029
Neuroprotective Properties of Melissa Officinalis L. Extract Against Ecstasy-Induced Neurotoxicity
https://pmc.ncbi.nlm.nih.gov/articles/PMC3652537/
Exploring Neuropsychiatric Manifestations of Vitamin B Complex Deficiencies (2025)
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2025.1569826/full
Application of Glycine in Children with Attention Deficit/Hyperactivity Disorder
https://biotiki.org/pdf-stati/28-ekkert_eng.pdf
Inositol and Sleep: Effects on Nocturnal Awakenings
https://austinpublishinggroup.com/sleep-disorders/fulltext/ajsd-v7-id1036.pdf
Anti-Stress Effects of Lemon Balm-Containing Foods (2014)
https://pmc.ncbi.nlm.nih.gov/articles/PMC4245564/
Phosphoinositides: Regulators of Nervous System Function in Health and Disease (2019)
https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2019.00208/full
Neurobiology and Applications of Inositol in Psychiatry: A Narrative Review (2023)
https://www.mdpi.com/1467-3045/45/2/113
Vitamin B6 and Its Role in Cell Metabolism and Physiology (2018)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6071262/
Vitamin B6 Nutrition, Metabolism, and the Relationship of Diseases: Current Concepts and Future Research (2025)
https://www.sciencedirect.com/science/article/pii/S2772566925000941
B Vitamins in the Nervous System: Current Knowledge of the Biochemical Modes of Action and Synergies of Thiamine, Pyridoxine, and Cobalamin (2019)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6930825/
Glycinergic Signaling in the Human Nervous System: An Overview of Therapeutic Drug Targets and Clinical Effects (2016)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6007534/
The Effect of Cognitive Behavioral Interventions Applied to Children with Anxiety Disorders on Their Anxiety Level: A Meta-Analysis Study (2024)
https://www.sciencedirect.com/science/article/abs/pii/S0882596324004652
Anxiety in Children
https://my.clevelandclinic.org/health/diseases/anxiety-in-children

Clinical Efficacy and Tolerability of Lemon Balm (Melissa officinalis L.) in Psychological Well-Being: A Review - PMC

Magne-Boost

https://pmc.ncbi.nlm.nih.gov/articles/PMC6071262/ Vitamin B6 and Its Role in Cell Metabolism and Physiology (2018)
https://www.sciencedirect.com/science/article/pii/S2772566925000941 Vitamin B6 Nutrition, Metabolism, and the Relationship of Diseases: Current Concepts and Future Research (2025)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6930825/ B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin (2019)
https://pmc.ncbi.nlm.nih.gov/articles/PMC12189353/ Unlocking the Power of Magnesium: A Systematic Review and Meta-Analysis Regarding Its Role in Oxidative Stress and Inflammation (2025)
https://www.ncbi.nlm.nih.gov/books/NBK507254/ Magnesium in neuroses and neuroticism
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1406455/full Neuroprotective effects of magnesium: implications for neuroinflammation and cognitive decline (2024)
https://pmc.ncbi.nlm.nih.gov/articles/PMC12535714/ The Mechanisms of Magnesium in Sleep Disorders (2025)
https://pubmed.ncbi.nlm.nih.gov/29480918/
Role of Magnesium in Vitamin D Activation and Function (2018)-activarea D3, sustinerea echilibrului calciu, fosfor
https://www.cell.com/iscience/fulltext/S2589-0042%2824%2902302-2
Modeling calcium and magnesium balance: Regulation by calciotropic hormones and adaptations under varying dietary intake (2024)
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/glycerophos… Glycerophosphate (2022)
https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/ Magnesium 60% in bones
https://www.mdpi.com/2073-8994/13/5/889 Phosphorus Compounds of Natural Origin: Prebiotic, Stereochemistry, Application (2021)
http://jpr.mazums.ac.ir/article-1-620-en.pdf Magnesium Status and Supplementation in Children With Attention-deficit/Hyperactivity Disorder: A Systematic Review
https://www.bahrainmedicalbulletin.com/MAR_2021/BMB-20-104.pdf Role of Serum Magnesium in Dental Caries (2021)
https://nhsdorset.nhs.uk/Downloads/aboutus/medicines-management/Other%20Guidelines/Management%20of%… The management of hypomagnesaemia in primary care
https://www.longdom.org/open-access-pdfs/type-of-magnesium-salt-and-formulation-solubility-determin… Type of Magnesium Salt and Formulation Solubility Determines
Bioavailability of Magnesium Food Supplements

Cold-Care Jr. Cough Syrup

https://pmc.ncbi.nlm.nih.gov/articles/PMC3609166/ Honey: its medicinal property and antibacterial activity (2011)
https://www.mdpi.com/1420-3049/30/4/919 Influence of Season, Hive Position, Extraction Method and Storage Temperature on Polyphenols and Antioxidant Activity of Croatian Honey (2025)
https://www.mdpi.com/1422-0067/25/19/10606 Polyphenols as the Main Compounds Influencing the Antioxidant Effect of Honey—A Review (2025)
https://www.mdpi.com/2079-6382/14/7/697 Multifaceted Biological Properties of Verbascoside/Acteoside: Antimicrobial, Cytotoxic, Anti-Inflammatory, and Immunomodulatory Effects (2025) https://archivepp.com/storage/models/article/YqwXaQqt0YLt4E3Wws0FJoo5FaUEoBQKaMSdBOIz4c6wg2MthMGABf… A pilot study of efficacy and safety of Plantago lanceolata and Primula veris, in the treatment of the common cold (2020)
https://karger.com/cmr/article-abstract/27/3/174/67787/Marsh-Mallow-Althaea-officinalis-L-and-Its-P… Marsh Mallow (Althaea officinalis L.) and Its Potency in the Treatment of Cough (2019)
https://all-imm.com/index.php/aei/article/download/71/524/2549 Natural remedies for acute post-viral cough in children (2020)
https://www.sciencedirect.com/science/article/abs/pii/S0944711323000065 Apigenin ameliorates non-eosinophilic inflammation, dysregulated immune homeostasis and mitochondria-mediated
https://pmc.ncbi.nlm.nih.gov/articles/PMC11221770/ The therapeutic potential of Melissa officinalis L. hydroalcoholic extract and rosmarinic acid in a rat asthmatic model: A study on anti-inflammatory and antioxidant effects (2024)
https://www.sciencedirect.com/science/article/abs/pii/S0731708514000831
HPLC-DAD-ESI/MSn analysis of phenolic compounds for quality control of Grindelia robusta Nutt. and bioactivities (2014)
https://pmc.ncbi.nlm.nih.gov/articles/PMC8175998/
Antimicrobial, immunomodulatory and cytotoxic activities of green synthesized nanoparticles from Acacia honey and Calotropis procera (2021)
https://www.mdpi.com/2079-6382/14/3/255 Honey as a Natural Antimicrobial (2025)
https://europepmc.org/article/med/31609769 Biological effects of verbascoside and its anti-inflammatory activity on oral mucositis: a review of the literature. (2020)
https://carahealth.com/herbal-monographs/grindelia-grindelia-robusta
Grindelia (Grindelia robusta) - Traditional Indications. Pharmacognosy
https://www.researchgate.net/publication/364054135_Significance_and_efficacy_of_triterpene_saponin_…
https://www.sciencedirect.com/science/article/pii/S2590157524004115 Honey microbiota, methods for determining the microbiological composition and the antimicrobial effect of honey (2024)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6274450/ Rosmarinic acid attenuates airway inflammation and hyperresponsiveness in a murine model of asthma (2016)
https://altmedrev.com/wp-content/uploads/2019/02/v13-1-58.pdf Matricaria chamomilla - antispasmodic effect
https://journals.lww.com/aptb/Pages/default.aspx Rosmarinic acid improves tracheal smooth muscle responsiveness and lung pathological changes in ovalbumin-sensitized rats (2024)

Cold-Care Jr. Chewable Tablets

https://www.fda.gov/media/96830/download
GRAS Exemption Claim for Streptococcus salivarius K12

https://www.tga.gov.au/resources/resource/compositional-guidelines/streptococcus-salivarius-k12
Compositional guideline for 'Streptococcus salivarius K12' permitted for use in listed medicines

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928062/
Use of Streptococcus salivarius K12 in the prevention of streptococcal and viral pharyngotonsillitis in children

https://academic.oup.com/femsre/article/25/3/285/624045
Lantibiotics: structure, biosynthesis and mode of action

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912462/
The Effect of Oral Probiotics (Streptococcus Salivarius k12) on the Salivary Level of Secretory Immunoglobulin A, Salivation Rate, and Oral Biofilm: A Pilot Randomized Clinical Trial

https://www.mednews.care/wp-content/uploads/2021/10/influence-of-oral-probiotic-streptococcus-saliv…
Influence of Oral Probiotic Streptococcus salivarius K12 on Ear and Oral Cavity Health in Humans: Systematic Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000506/
Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, double-blind, placebo-controlled clinical study

https://www.mdpi.com/2673-8449/1/2/6
Involvement of Probiotics and Postbiotics in the Immune System Modulation

https://www.metagenicsinstitute.com.au/tech-data/Lactobacillus-plantarum-lactobacillus-paracasei-la…
Lactobacillus plantarum HEAL9, Lactobacillus paracasei 8700:2 and Lactobacillus rhamnosus LGG® to Boost Immunity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928062/
Use of Streptococcus salivarius K12 in the prevention of streptococcal and viral pharyngotonsillitis in children

https://blis.co.nz/blis-k12/ How does BLIS K12™ work?

https://pubmed.ncbi.nlm.nih.gov/20803023/
Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections

https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2021.805809/full

https://www.mdpi.com/2072-6643/9/11/1211

Cold-Care Cough Syrup

https://archivepp.com/storage/models/article/YqwXaQqt0YLt4E3Wws0FJoo5FaUEoBQKaMSdBOIz4c6wg2MthMGABf…
https://karger.com/cmr/article-abstract/27/3/174/67787/Marsh-Mallow-Althaea-officinalis-L-and-Its-P…
https://all-imm.com/index.php/aei/article/download/71/524/2549
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175146/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10094145/

https://www.mdpi.com/2304-8158/12/15/2975

https://pmc.ncbi.nlm.nih.gov/articles/PMC10302218/

https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.202…

Cold-Care Chewable Tablets

https://www.sciencedirect.com/science/article/pii/S1756464614002400
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335834/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893770/
https://iubmb.onlinelibrary.wiley.com/doi/pdf/10.1002/iub.1189
https://all-imm.com/index.php/aei/article/download/71/524/2549
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158017/
https://pubmed.ncbi.nlm.nih.gov/32779416/
https://dergipark.org.tr/tr/download/article-file/610620
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095832/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347422/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037471/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880174/

Daily-D3 500 IU Jr.

https://www.insmc.ro/wp-content/uploads/2021/01/Protocol_anemie_si_rahitism_carential_la_copil.pdf Cf. Protocolului pentru profilaxia rahitismului la copil, aprobat de Ministerul Sănătății, Institutul pentru Ocrotirea Mamei și Copilului, „Prof. Dr. Alfred Rusescu” (2010)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928729 / Vitamina D în sănătatea copiilor (2013)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900346 / Dermatita atopică și vitamina D: fapte și controverse (2013)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671203 / Are vitamina D un rol în diabet? (2022)
https://pubmed.ncbi.nlm.nih.gov/32751111 /Reglarea filagrinei, loricrinei și involucrinei de către IL-4, IL-13, IL-17A, IL-22, AHR și NRF2: Implicații patogene în dermatita atopică (2020)
https://www.mdpi.com/2072-6643/16/11/1595 Explorarea potențialului preventiv al vitaminei D împotriva infecțiilor respiratorii la copiii de vârstă preșcolară: un studiu transversal (2024)
https://karger.com/iaa/article/157/2/168/161946/Vitamin-D-Deficiency-as-a-Strong-Predictor-of Deficitul de vitamina D ca predictor puternic al astmului la copii (2012)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610869/Efectele rahitismului cu deficit de vitamina D la început de viață asupra sănătății oaselor și dentare, creșterii și imunității (2015)
https://www.sciencedirect.com/science/article/abs/pii/S1364032122004683 Ulei de cocos – perspective privind siguranța mediului și sustenabilitatea (2022)
https://pmc.ncbi.nlm.nih.gov/articles/PMC10060648/ Vitamin D in pediatric age: Current evidence, recommendations, and misunderstandings (2023)
https://www.mdpi.com/2072-6694/16/24/4201 Sunt pacienții pediatrici cu cancer un grup de risc pentru deficitul de vitamina D? O analiză sistematică (2024)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6179511/ Deficitul de vitamina D și obezitatea infantilă: povestea a două epidemii (2014)
https://pmc.ncbi.nlm.nih.gov/articles/PMC9610817/ Vitamin D and the Central Nervous System: Causative and Preventative Mechanisms in Brain Disorders (2022)
https://pubmed.ncbi.nlm.nih.gov/31269890/ The Effect of Vitamin D3 Supplementation on Serum BDNF, Dopamine, and Serotonin in Children with Attention-Deficit/Hyperactivity Disorder (2019)
https://www.mdpi.com/1422-0067/26/11/5005 Vitamin D in the Prevention and Treatment of Inflammatory Skin Diseases (2025)
https://pmc.ncbi.nlm.nih.gov/articles/PMC3256336/ Antimicrobial implications of vitamin D (20110
https://www.mdpi.com/2072-6643/16/23/4128 Vitamin D Supplementation for Treating Atopic Dermatitis in Children and Adults: A Systematic Review and Meta-Analysis (2024)
https://pmc.ncbi.nlm.nih.gov/articles/PMC12174595/ The effects of prenatal vitamin D supplementation on respiratory and allergy-related outcomes in children: A systematic review and meta-analysis of randomized controlled trials (2025)
https://www.tandfonline.com/doi/full/10.1080/10408363.2022.2070595
Vitamin D: sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its metabolites (2022)
https://www.sciencedirect.com/science/article/abs/pii/S0960076019306090
Vitamin D and intestinal homeostasis: Barrier, microbiota, and immune modulation (2020)
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.950465/full
Acțiuni imunomodulatoare ale vitaminei D în diverse tulburări imune: o analiză cuprinzătoare (2023)
https://pmc.ncbi.nlm.nih.gov/articles/PMC4340987/
Vitamin D3 influence the Th1/Th2 ratio in C57BL/6 induced model of experimental autoimmune encephalomyelitis (2014)
https://pubmed.ncbi.nlm.nih.gov/24335055/
Vitamin D supplementation increases calcium absorption without a threshold effect (2013)
https://pubmed.ncbi.nlm.nih.gov/11332696/
Decrease in calcitonin and parathyroid hormone mRNA levels and hormone secretion under long-term hypervitaminosis D3 in rats (2001)

Uro-Balance Jr.