Bibliografie broșură Sistem Nervos

Neuro Optimizer®

2.https://nutraceuticalbusinessreview.com/cognizin-citicoline-nutraingredients-award-winner-europe-2022-201299 - Cognizin® Citicoline

3.https://pmc.ncbi.nlm.nih.gov/articles/PMC9382310/ -Phosphatidylserine, inflammation, and central nervous system diseases (2022)

4.https://www.sciencedirect.com/science/article/abs/pii/S1878764917300037 -Effect of acetyl-l-carnitine in the treatment of diabetic peripheral neuropathy: A systematic review and meta-analysis (2017)

5.https://pmc.ncbi.nlm.nih.gov/articles/PMC10479846/ - Emergence of taurine as a therapeutic agent for neurological disorders (2023)

6.https://www.naturalmedicinejournal.com/journal/citicoline-novel-therapeutic-agent-neuroprotective-neuromodulatory-and - Citicoline: A Novel Therapeutic Agent with Neuroprotective, Neuromodulatory, and Neuroregenerative Properties (2014)

7.https://mhanational.org/resources/what-is-acetylcholine/ -What is Acetylcholine?

8.https://pubmed.ncbi.nlm.nih.gov/21703569/- CDP-choline as a biological supplement during neurorecovery: a focused review (2011)

9.https://journals.sagepub.com/doi/10.1177/26331055231152496 -Role of Citicoline in Patients With Mild Cognitive Impairment (2023)

10.https://healthsciences.iff.com/our-products/sharp-ps-brain - Sharp-PS® for Brain Health

11.https://pubmed.ncbi.nlm.nih.gov/23495677/-The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial (2014)

12.https://www.naturalhealthresearch.org/wp-content/uploads/2017/11/Phosphatidylserine-Fortified-Milk-Associated-with-Enhanced-Cognitive-Performance.pdf -Research on human memory enhancement by phosphatidylserine, fortified milk (2017)

13.https://pmc.ncbi.nlm.nih.gov/articles/PMC9382310/-Phosphatidylserine, inflammation, and central nervous system diseases (2022)

14.https://pmc.ncbi.nlm.nih.gov/articles/PMC7760805/ -The Possible Importance of Glutamine Supplementation to Mood and Cognition in Hypoxia from High Altitude (2020)

15.https://pmc.ncbi.nlm.nih.gov/articles/PMC8139993/-Potential Neuroregenerative and Neuroprotective Effects of Uridine/Choline-Enriched Multinutrient Dietary Intervention for Mild Cognitive Impairment: A Narrative Review (2020)

16.https://pubmed.ncbi.nlm.nih.gov/27186142/- Current knowledge on the neuroprotective and neuroregenerative properties of citicoline in acute ischemic stroke (2015)

17.https://pmc.ncbi.nlm.nih.gov/articles/PMC4258547/-Phosphatidylserine in the Brain: Metabolism and Function (2015)

18.https://pubmed.ncbi.nlm.nih.gov/27100509/-The neurobiology of acetyl-L-carnitine (2016)

19.https://pmc.ncbi.nlm.nih.gov/articles/PMC8066453/- Citicoline: A Candidate for Adjunct Treatment of Multiple Sclerosis (2021)

20.https://pubmed.ncbi.nlm.nih.gov/33279231/- Citicoline as Adjuvant Therapy in Parkinson's Disease: A Systematic Review (2020)

21.https://pmc.ncbi.nlm.nih.gov/articles/PMC10802721/-Nutraceuticals and phytoceuticals in the treatment of schizophrenia: a systematic review and network meta-analysis (2024)

22.https://pubmed.ncbi.nlm.nih.gov/18799816/-Benzodiazepine/GABA(A) receptors are involved in magnesium-induced anxiolytic-like behavior in mice (2008)

23.https://www.ncbi.nlm.nih.gov/books/NBK526124/ -GABA Receptor (2023)

24.https://mhanational.org/resources/what-is-glutamate/ - What is Glutamate?

25.https://www.sciencedirect.com/science/article/abs/pii/B9780124114623000229 -Chapter 22 - The Effects of Taurine Exposure on the Brain and Neurological Disorders (2015)

26.https://qbi.uq.edu.au/brain-basics/brain/brain-physiology/long-term-synaptic-plasticity -Long-term synaptic plasticity

27.https://pmc.ncbi.nlm.nih.gov/articles/PMC7760805/-The Possible Importance of Glutamine Supplementation to Mood and Cognition in Hypoxia from High Altitude (2020)

28.https://www.biomolther.org/journal/view.html?uid=948&vmd=Full -Effects and Mechanisms of Taurine as a Therapeutic Agent (2018)

29.https://pubmed.ncbi.nlm.nih.gov/27100509/- The neurobiology of acetyl-L-carnitine (2016)

30.https://www.shutterstock.com/ro/image-vector/neurons-neuroglial-cells-glial-nonneuronal-brain-235015666?dd_referrer=https%3A%2F%2Fstatics.teams.cdn.office.net%2F - Neuronii și celule gliale

31.https://pmc.ncbi.nlm.nih.gov/articles/PMC9952911/- Dynamic Regulation of DNA Methylation and Brain Functions (2023)

32.https://pubmed.ncbi.nlm.nih.gov/33978188/- Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial (2021)

33. https://pubmed.ncbi.nlm.nih.gov/15365617/- Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells (2004)

55.https://www.sciencedirect.com/science/article/abs/pii/S003193841830636X?via%3Dihub-Influence of citicoline on citalopram-induced antidepressant activity in depressive-like symptoms in male mice (2018)

56.https://onlinelibrary.wiley.com/doi/10.1111/jnc.12269- Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke (2013)

57.https://www.journalofsurgicalresearch.com/article/S0022-4804(15)00949-X/abstract%20CDP-Choline modulates matrix metalloproteinases in rat sciatic injury (2016)

95. https://ro.wikipedia.org/wiki/Fi%C8%99ier:Neuron_ro.gif Structura neuronului

Train-Your-Brain® cps

7.https://mhanational.org/resources/what-is-acetylcholine/ -What is Acetylcholine?

20.https://pubmed.ncbi.nlm.nih.gov/33279231/- Citicoline as Adjuvant Therapy in Parkinson's Disease: A Systematic Review (2020)

22.https://pubmed.ncbi.nlm.nih.gov/18799816/-Benzodiazepine/GABA(A) receptors are involved in magnesium-induced anxiolytic-like behavior in mice (2008)

23.https://www.ncbi.nlm.nih.gov/books/NBK526124/ -GABA Receptor (2023)

34.https://pubmed.ncbi.nlm.nih.gov/27100509/- The neurobiology of acetyl-L-carnitine (2016)

35.https://pmc.ncbi.nlm.nih.gov/articles/PMC7387066/-Association between Vitamin B12 levels and cognitive function in the elderly Korean population (2020)

37.https://pubmed.ncbi.nlm.nih.gov/37447150/-The Role of Vitamin B6 in Peripheral Neuropathy: A Systematic Review (2023)

38.https://pubmed.ncbi.nlm.nih.gov/37670573/-Pharmacological and Nonpharmacological Treatments for Painful Diabetic Peripheral Neuropathy (2023)

39.https://pmc.ncbi.nlm.nih.gov/articles/PMC6930825/#:~:text=The%20role%20of%20pyridoxine%20in,responsible%20for%20the%20synthesis%20of- B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin (2019)

96. https://examine.com/supplements/bacopa-monnieri/research/#neurology_memory - Bacopa Monnieri (2023)

97.https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00849/full - Potential Therapeutic Effects of Lipoic Acid on Memory Deficits Related to Aging and Neurodegeneration (2017)

Train-Your-Brain® 9 FIOLE BUVABILE

34.https://pubmed.ncbi.nlm.nih.gov/27100509/- The neurobiology of acetyl-L-carnitine (2016)

35.https://pmc.ncbi.nlm.nih.gov/articles/PMC7387066/-Association between Vitamin B12 levels and cognitive function in the elderly Korean population (2020)

36.https://link.springer.com/article/10.1007/s11101-017-9528-y - Centella asiatica: phytochemistry and mechanisms of neuroprotection and cognitive enhancement (2017)

37.https://pubmed.ncbi.nlm.nih.gov/37447150/-The Role of Vitamin B6 in Peripheral Neuropathy: A Systematic Review (2023)

38.https://pubmed.ncbi.nlm.nih.gov/37670573/-Pharmacological and Nonpharmacological Treatments for Painful Diabetic Peripheral Neuropathy (2023)

50.https://examine.com/supplements/rhodiola-rosea/research/ -Rhodiola Rosea (2023)

Uridine 250 mg

40.https://my.klarity.health/magnesium-for-nerve-pain/ -Magnesium for Nerve Pain (2023)

41.https://pmc.ncbi.nlm.nih.gov/articles/PMC5095804/-Synaptopathies: synaptic dysfunction in neurological disorders – A review from students to students (2016)

42.https://www.sciencedirect.com/science/article/pii/S0969996122003448-Schwann cell functions in peripheral nerve development and repair (2023)

43.https://www.nature.com/articles/srep32623 -Low serum magnesium levels are associated with impaired peripheral nerve function in type 2 diabetic patients (2016)

44.https://pmc.ncbi.nlm.nih.gov/articles/PMC8385315/ -Magnesium Promotes the Regeneration of the Peripheral Nerve (2021)

45.https://pmc.ncbi.nlm.nih.gov/articles/PMC10937367/ -Uridine and its role in metabolic diseases, tumors, and neurodegenerative diseases (2024)

Mag-Your-Mind®

46.https://pmc.ncbi.nlm.nih.gov/articles/PMC5637834/ -The Importance of Magnesium in Clinical Healthcare (2017)

47.https://www.medicalnewstoday.com/articles/315372 -The uses and benefits of magnesium glycinate (2023)

48.https://www.researchgate.net/publication/227185267_Glycine_as_a_neurotransmitter_in_the_forebrain_A_short_review -Glycine as a neurotransmitter in the forebrain: A short review (2009)

49.https://pubmed.ncbi.nlm.nih.gov/20308973/ -Effects of chronic Rhodiola Rosea supplementation on sport performance and antioxidant capacity in trained male: preliminary results (2010)

50.https://examine.com/supplements/rhodiola-rosea/research/ -Rhodiola Rosea (2023)

51.https://examine.com/supplements/schisandra/research/ -Schisandra (2024)

52.https://pmc.ncbi.nlm.nih.gov/articles/PMC6930825/-B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin (2019)

53.https://pmc.ncbi.nlm.nih.gov/articles/PMC1737896/pdf/v072p00567.pdf-Benefits and risks of folic acid to the nervous system (2006)

54.https://www.ncbi.nlm.nih.gov/books/NBK507271/-Magnesium in headache (2023)

58. https://www.mdpi.com/2072-6643/12/8/2184- Magnesium and Pain (2020)

65. https://www.sciencedirect.com/science/article/abs/pii/S1567576916301199 -Schisandrin B inhibits Th1/Th17 differentiation and promotes regulatory T cell expansion in mouse lymphocytes (2016)

93. https://pubmed.ncbi.nlm.nih.gov/28219059/ - Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial (2017)

Good-Night

68. https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002587- Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial (2018)

69. https://www.sciencedirect.com/science/article/abs/pii/S0965229919303711- A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study (2019)

70. https://pmc.ncbi.nlm.nih.gov/articles/PMC5637834/- The Importance of Magnesium in Clinical Healthcare (2017)

71.https://www.researchgate.net/publication/24198940_Does_valerian_improve_sleepiness_and_symptom_severity_in_people_with_restless_legs_syndrome- Does valerian improve sleepiness and symptom severity in people with restless legs syndrome? (2009)

72. https://www.mayoclinic.org/diseases-conditions/insomnia/symptoms-causes/syc-20355167- Insomnia (2024)

73.https://www.ema.europa.eu/en/documents/herbal-summary/valerian-root-and-hop-strobile-summary-public_en.pdf- Valerian root and hop strobile (2019)

74. https://www.medicalnewstoday.com/articles/323795 - Benefits of passionflower for anxiety and insomnia (2023)

75.https://pdfs.semanticscholar.org/1d64/ee455218db3781457988033ef26cf8264b95.pdf- Updating the biological interest of Valeriana officinalis (2021)

76.https://www.researchgate.net/publication/227185267_Glycine_as_a_neurotransmitter_in_the_forebrain_A_short_review- Glycine as a neurotransmitter in the forebrain: A short review (2009)

77.https://pmc.ncbi.nlm.nih.gov/articles/PMC6930825/#:~:text=The%20role%20of%20pyridoxine%20in,responsible%20for%20the%20synthesis%20of- B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin (2019)

78.https://www.whatishealth.net/single-post/the-connection-between-melatonin-cortisol-light-and-your-sleep- The Connection Between Melatonin, Cortisol, Light and Your Sleep!

5-HTP

79. https://pmc.ncbi.nlm.nih.gov/articles/PMC7796270/-5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology (2020)

80. https://bebrainfit.com/serotonin-supplements/ - Serotonin Supplements to Boost Mood Naturally (detailed guide) (2025)

81.https://www.researchgate.net/publication/7721946_Serotonin_a_la_carte_Supplementation_with_the_serotonin_precursor_5-hydroxytryptophan- Serotonin a la carte: Supplementation with the serotonin precursor 5-hydroxytryptophan (2006)

82. https://pubmed.ncbi.nlm.nih.gov/33375373/- 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology (2020)

89. https://farmaciajournal.com/issue-articles/5-hydroxitryptophan-dietary-supplementation-in-post-traumatic-stress-syndrome/ - 5-hydroxitryptophan dietary supplementation in post-traumatic stress syndrome (2022)

90.https://restorativemedicine.org/journal/menstrual-cycle-fluctuations-progesterone-effect-sleep-regulation/-Menstrual Cycle Fluctuations of Progesterone and the Effect on Sleep Regulation (2020)

91. https://www.sciencedirect.com/science/article/abs/pii/S1569733910700898-CHAPTER 3.4 - Serotonin and Sexual Behavior (2010)

94. https://onlinelibrary.wiley.com/doi/10.1002/eji.201847525 -Serotonin decreases the production of Th1/Th17 cytokines and elevates the frequency of regulatory CD4+ T-cell subsets in multiple sclerosis patients (2018)

Vitamin B-Complex

83.https://pmc.ncbi.nlm.nih.gov/articles/PMC6910806/- The Effects of Magnesium – Melatonin - Vit B Complex Supplementation in Treatment of Insomnia (2019)

84. https://www.mdpi.com/2072-6643/14/16/3367- Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs (2022)

85. https://pmc.ncbi.nlm.nih.gov/articles/PMC11898261/- Nutritional therapies in psychiatric disorders. Alternative Medicine Review. Gaby, A.R. (2017).

86.https://pmc.ncbi.nlm.nih.gov/articles/PMC9955821/ - Neurobiology and Applications of Inositol in Psychiatry: A Narrative Review (2023)

87.https://pubmed.ncbi.nlm.nih.gov/16848706/- Choline: critical role during fetal development and dietary requirements in adults (2006)

88.https://pubmed.ncbi.nlm.nih.gov/20838622/ - Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial (2010)

92.https://pubmed.ncbi.nlm.nih.gov/16510043/- Homocysteine: role and implications in atherosclerosis (2006)

Alpha GPC 300mg

98.https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=6cfe2f1a2b25e7ba36a3efb695b9564a82e5a8cb - GlyceroPhosphoCholine (GPC); Mind-Body Nutrient for Active Living And Healthy Aging (2005)

99. https://examine.com/supplements/alpha-gpc/#neurology_dopaminergic-neurotransmission - Alpha-GPC; Research Analysis (2018)

100. https://jissn.biomedcentral.com/articles/10.1186/s12970-015-0093-2- The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength; Journal of the International Society of Sports Nutrition (2015)

SAM-e 200mg

101. https://www.sciencedirect.com/science/article/pii/S0002916523060306 - S-Adenosyl-L-methionine (SAMe): from the bench to the bedside—molecular basis of a pleiotrophic molecule (2002)

102. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107756 - The Effect of S-Adenosylmethionine on Cognitive Performance in Mice: An Animal Model Meta-Analysis (2014)

103. https://altmedrev.com/2003/07/sports-nutrition-selected-nutritional-supplements-for-bodybuilders-and-strength-athletes/ - Sports Nutrition: Selected Nutritional Supplements For Bodybuilders and Strength Athletes (1997)

104. https://examine.com/supplements/s-adenosyl-methionine/ - S-Adenosylmethionine (SAM-e) – Research Summary (2023)

GABA 750mg

105. https://www.frontiersin.org/articles/10.3389/fpsyg.2015.01520/full - Neurotransmitters as food supplements: the effects of GABA on brain and behavior (2015)

106. https://draxe.com/nutrition/gaba/ - What Is GABA? The Brain-Boosting, Anxiety-Busting Power of GABA Supplement (2017)

Pure Omega-3

107. https://doi.org/10.1016/j.pain.2007.01.020 - A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain. Pain. (2007)

108. https://doi.org/10.3390/md16080256 - Cosmetic and Therapeutic Applications of Fish Oil's Fatty Acids on the Skin. (2018)

109. https://www.sciencedirect.com/science/article/pii/S241464472030004X - Omega-3 fatty acids and mental health (2020)

110. https://www.mdpi.com/2072-6643/12/8/2191 - The Association between Omega-3 Fatty Acid Intake and Human Brain Connectivity in Middle-Aged Depressed Women (2020)

111. https://n.neurology.org/content/82/5/435 - Higher RBC EPA + DHA corresponds with larger total brain and hippocampal volumes: WHIMS-MRI Study. (2014)

Ashwagandha SE 500mg

112. Ruchi Tiwari, Sandip Chakraborty et. Al., "Ashwagandha (Withania somnifera): Role in Safeguarding Health, Immunomodulatory Effects, Combating Infections and Therapeutic Applications: A Review", Journal of Biological Sciences, Volume 14 (2): 77-94, 2014

113. https://violapharm.com/en/ashwagandha-withania-somnifera -Ashwagandha (Withania somnifera): a scientific look at adaptogenic and neuroprotective properties(2025)

Coenzyme Q10

114. https://www.mayoclinic.org/drugs-supplements-coenzyme-q10/art-20362602 - Coenzyme Q10 – Uses, Side Effects and More
115. https://www.indena.com/product/ubiqsome/ - Ubiqsome® – Phytosome® of Coenzyme Q10
116. https://www.indena.com/indena_files/2022/03/ubiqsome_ss_int.pdf - Ubiqsome® Supplement Sheet (2022)
117. https://www.sciencedirect.com/science/article/abs/pii/S1567724907000591 - Coenzyme Q10: clinical applications and efficacy (2007)

118. https://www.frontiersin.org/articles/10.3389/fphar.2022.883251/full - Role of CoQ10 in the nervous system: potential and evidence (2022)
119. Evidence for a protective effect of endogenous Ubiquinol against oxidative damage to mitochondrial – Forsmark-Andrée & Ernster
120. https://doi.org/10.3390/antiox11071360 - Effects of Coenzyme Q10 Supplementation on Biomarkers of Oxidative Stress in Adults: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials. (2022)
121. https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/biof.1839 - Coenzyme Q10 and cellular bioenergetics (2020)
122. https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2010.1793 - Scientific Opinion on the safety of CoQ10 as novel food – EFSA Journal (2010)
123. Effects of CoQ10 on performance and oxidative stress – Sarmiento et al.
124. American Heart Association Supplement to Circulation. October 28, 2003. Vol. 108 (17), pg. 739. Belardinelli, RM et al.
125. https://www.fortunejournals.com/articles/efficient-muscle-distribution-reflects-the-positive-influence-of-coenzyme-q10-phytosome-in-healthy-aging-athletes-after-stressing-.html - Efficient muscle distribution reflects the positive influence of Coenzyme Q10 Phytosome®
126. https://article.imrpress.com/bri/Landmark/articles/pdf/Landmark4231.pdf - Landmark CoQ10 report PDF
127. https://www.ahajournals.org/doi/10.1161/JAHA.118.009835 - Heart health and CoQ10 – JAHA (2018)
128. https://www.mayoclinic.org/drugs-supplements-coenzyme-q10/art-20362602
129. https://www.indena.com/indena_files/2020/01/wp_phytosome_int.pdf - White Paper – Phytosome® CoQ10 (2020)

Resveratrol Bioactive 250 mg

130. https://pmc.ncbi.nlm.nih.gov/articles/PMC3123408/ - Mitochondrial Protection by Resveratrol (2011)

131. https://pmc.ncbi.nlm.nih.gov/articles/PMC5707673/- Epigenetic Regulatory Mechanisms Induced by Resveratrol (2017)

132. https://www.sciencedirect.com/science/article/pii/S2772753X2300360X - Resveratrol as a privileged molecule with antioxidant activity (2023)

133. https://pmc.ncbi.nlm.nih.gov/articles/PMC7796143/ - Anti-Inflammatory Action and Mechanisms of Resveratrol (2021)

134. https://pmc.ncbi.nlm.nih.gov/articles/PMC8289612/ - Effects and Mechanisms of Resveratrol on Aging and Age-Related Diseases (2021)

135. https://link.springer.com/article/10.1007/s12035-019-01803-6 - Resveratrol Activates Neuronal Autophagy Through AMPK in the Ischemic Brain (2019)

136. https://www.sciencedirect.com/science/article/abs/pii/S0166432818304121 - Resveratrol prevents cognitive deficits induced by chronic unpredictable mild stress: Sirt1/miR-134 signalling pathway regulates CREB/BDNF expression in hippocampus in vivo and in vitro (2018)

137. https://pubmed.ncbi.nlm.nih.gov/16207717/ - Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival (2005)

138. https://www.nature.com/articles/s41598-017-06231-x - CREB Regulates Distinct Adaptive Transcriptional Programs in Astrocytes and Neurons (2017)

139.https://www.researchgate.net/publication/236054361_Acute_effects_of_resveratrol_to_enhance_cocaine-induced_dopamine_neurotransmission_in_the_striatum Acute effects of resveratrol to enhance cocaine-induced dopamine neurotransmission in the striatum (2013)

140. https://pubmed.ncbi.nlm.nih.gov/28911531/ - Biological actions and molecular effects of resveratrol, pterostilbene, and 3'-hydroxypterostilbene (2017)

141. https://pubmed.ncbi.nlm.nih.gov/30205595/ - Resveratrol: A Double-Edged Sword in Health Benefits (2018)

Glutathione Reduced 500mg

142. Vivek Kumar Bains, Rhythm Bains, " The antioxidant master glutathione and periodontal health", Dent Res J (Isfahan). 2015 Sep-Oct; 12(5): 389–405.
143. Guoyao Wu, Yun-Zhong Fang et. Al., " Glutathione Metabolism and Its Implications for Health", The Journal of Nutrition, Volume 134, Issue 3, March 2004, Pages 489–492.
144. Lien Ai Pham-Huy, Hua He et. Al., " Free Radicals, Antioxidants in Disease and Health", Int J Biomed Sci. 2008 Jun; 4(2): 89–96.
145. https://doi.org/10.1155/2012/736837 - Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions", Journal of Amino Acids (2012)

Magnesium 500 mg

59. https://pubmed.ncbi.nlm.nih.gov/30562392/- Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial (2018)

60.https://pubmed.ncbi.nlm.nih.gov/26404370/- Magnesium in Prevention and Therapy (2015)

61.https://pubmed.ncbi.nlm.nih.gov/19621856/ - Therapeutic uses of magnesium (2009)

62.https://europepmc.org/article/MED/29123461- Intestinal Absorption and Factors Influencing Bioavailability of Magnesium-An Update. (2017)

63.https://biologyinsights.com/magnesium-and-neuropathy-the-link-and-potential-effects/- Magnesium and Neuropathy: The Link and Potential Effects (2025)

64. https://www.sciencedirect.com/science/article/pii/S8756328221003999- Impact of magnesium on bone health in older adults: A systematic review and meta-analysis (2022)

66.https://pubmed.ncbi.nlm.nih.gov/37846572/- Potassium Magnesium Citrate Is Superior to Potassium Chloride in Reversing Metabolic Side Effects of Chlorthalidone (2023)

67. https://academic.oup.com/nar/article/44/17/8456/2468054- Effect of magnesium ions on the structure of DNA thin films: an infrared spectroscopy study (2016)

Good-Aging

146.https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1359176/full - Apigenin: a natural molecule at the intersection of sleep and aging (2024)
147. https://pmc.ncbi.nlm.nih.gov/articles/PMC8289612/- Effects and Mechanisms of Resveratrol on Aging and Age-Related Diseases (2021)
148. https://pmc.ncbi.nlm.nih.gov/articles/PMC10722989/ - Exploring the anti-aging effects of fisetin in telomerase-deficient progeria mouse model (2023)
149. https://www.sciencedirect.com/science/article/pii/S0047637424000952 - Fisetin as a senotherapeutic agent: Evidence and perspectives for age-related diseases (2024)
150. https://www.sciencedirect.com/science/article/abs/pii/S004763741300050X - The autophagy enhancer spermidine reverses arterial aging (2013)
151. https://hal.science/hal-04702724v1/document - Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans? (2019)
152. https://pmc.ncbi.nlm.nih.gov/articles/PMC8612618/ - New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases (2021)
153. https://www.maturitas.org/article/S0378-5122(24)00186-5/fulltext - The impact of carnosine on biological ageing – A geroscience approach (2024)
154. https://pubmed.ncbi.nlm.nih.gov/29858687/ - Carnosine and advanced glycation end products: a systematic review (2018)
155. https://pmc.ncbi.nlm.nih.gov/articles/PMC3836174/ - The Hallmarks of Aging (2013)
156. https://pubmed.ncbi.nlm.nih.gov/29185343/ - Pyrroloquinoline Quinone, a Redox-Active o-Quinone, Stimulates Mitochondrial Biogenesis by Activating the SIRT1/PGC-1α Signaling Pathway (2017)
157.https://academic.oup.com/carcin/article-abstract/33/1/149/2463617 - Resveratrol protects mouse embryonic stem cells from ionizing radiation by accelerating recovery from DNA strand breakage (2011)
158. https://cajmhe.com/index.php/journal/article/view/48 - Spermidine maintains telomere length and delays aging (2021)
159. https://pmc.ncbi.nlm.nih.gov/articles/PMC7350017/ Genome -Protecting Compounds as Potential Geroprotectors (2020)
160. https://pmc.ncbi.nlm.nih.gov/articles/PMC3746174/- Sirtuin 1 and sirtuin 3: physiological modulators of metabolism (2013)
161. https://www.mgcpqq.eu/about/ - MGCPQQ
162. https://www.mdpi.com/2073-4409/12/23/2742 - Unraveling the Intricacies of Autophagy and Mitophagy: Implications in Cancer Biology (2023)
163. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737637/ - NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism (2018)
164.https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2024.1393181/full - SIRT1, resveratrol and aging (2024)
165. https://pubmed.ncbi.nlm.nih.gov/38421057/ - Therapeutic effects of resveratrol on epigenetic mechanisms in aging (2024)
166. https://pmc.ncbi.nlm.nih.gov/articles/PMC9068308/ - Interventiones nutritionales cum plantarum compositis in senescentia cellular (2022)
167.https://www.nature.com/articles/s41392-024-01888-z/- Communicatio cellula-cellula: novae prospectus et implicationes clinicae (2024)
168. https://pmc.ncbi.nlm.nih.gov/articles/PMC2915624/ - Munus nicotinamidae in DNA detrimento, mutagenesi et reparation (2010)
169. pmc.mcbi.nlm.nih.gov/articles/PMC10196175 -PQQ ad reducendam adipem accumulationem et progressionem obesitatis (2023)
170. https://pmc.ncbi.nlm.nih.gov/articles/PMC5707673/ - Mechanismi epigenetici a resveratrolo inducti (2017)
171. https://orthomolecular.org/resources/omns/v17n05.shtml - Niacin and Cancer
How vitamin B-3 protects and even helps repair your DNA (2021)
172. https://www.sciencedirect.com/science/article/pii/S2090123224000055 - Resveratrol and p53: How are they involved in CRC plasticity and apoptosis (2024)
173.https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.1031438/full - Resveratrol activates CD8+ T cells through IL-18 bystander activation in lung adenocarcinoma (2022)
174.https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1368949/full -Resveratrol and vascular health: evidence from clinical studies and mechanisms of actions related to its metabolites produced by gut microbiota (2024)
175. https://www.sciencedirect.com/science/article/abs/pii/B9780128144664000136
Chapter 13 - Pyrroloquinoline Quinone: Its Profile, Effects on the Liver and Implications for Health and Disease Prevention (2019)
175. https://pubs.rsc.org/en/content/articlelanding/2020/fo/d0fo00949/full

-Apigenin induced autophagy and stimulated autophagic lipid degradation (2020)
176. https://www.sciencedirect.com/science/article/abs/pii/S0024320519300992 - Fisetin ameliorates oxidative stress, inflammation and apoptosis in diabetic cardiomyopathy (2019)
177. https://pubmed.ncbi.nlm.nih.gov/27040154/ - Effects of carnosine supplementation on glucose metabolism: Pilot clinical trial (2016)
178.https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2022.795980/full - Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic ReviewUpdated (2022)
179. https://pmc.ncbi.nlm.nih.gov/articles/PMC7369269/ - Pyrroloquinoline quinone can prevent chronic heart failure by regulating mitochondrial function (2020)
180.https://www.biorxiv.org/content/10.1101/2024.12.04.626625v1.full.pdf -
Spermidine alleviates depression via control of the stress response (2024)
181. https://pubmed.ncbi.nlm.nih.gov/33228716/ - Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice (2020)
182. https://pubmed.ncbi.nlm.nih.gov/25702528/ - Pyrroloquinoline quinone against glutamate-induced neurotoxicity in cultured neural stem and progenitor cells (2025)
183. https://www.cambridge.org/core/journals/experimental-results/article/pyrroloquinoline-quinone-influences-intracellular-alphasynuclein-aggregates/99A3C944C752CDA53E9347F27D1C71BC - Pyrroloquinoline quinone influences intracellular alpha-synuclein aggregates (2023)
184. https://pubs.acs.org/doi/abs/10.1021/acschemneuro.8b00355 - Esterification of PQQ Enhances Blood-Brain Barrier Permeability and Inhibitory Activity against Amyloidogenic Protein Fibril Formation (2018)
185. https://www.tandfonline.com/doi/full/10.4161/pri.4.1.10889 - Pyrroloquinoline quinone inhibits the fibrillation of amyloid proteins (2010)
186. https://www.mdpi.com/2227-9059/11/11/2878 - An Overview of Recent Advances in the Neuroprotective Potentials of Fisetin against Diverse Insults in Neurological Diseases and the Underlying Signaling Pathways (2023)
187. https://kompetenz-statt-demenz.dsgip.de/en/prevention-treatment/micronutrients/spermidine -The polyamine spermidine and its neuroprotective effect in Alzheimer’s disease (2022)

188. https://www.sciencedirect.com/science/article/pii/S0925443914002920 -
Neuroprotective action of resveratrol (2015)
189. https://www.sciencedirect.com/science/article/pii/S2213453023000964 - Apigenin, a natural flavonoid, promotes autophagy and ferroptosis in human endometrial carcinoma Ishikawa cells in vitro and in vivo (2023)
190.https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.960601/full - Fisetin reduces the senescent tubular epithelial cell burden and also inhibits proliferative fibroblasts in murine lupus nephritis (2022)
191. https://www.sciencedirect.com/science/article/pii/S2666459325000095- Protective effects of apigenin in neurodegeneration: An update on the potential mechanisms (2025)
192. https://academic.oup.com/stmcls/article/41/7/698/7190776 - Fisetin Attenuates Cellular Senescence Accumulation During Culture Expansion of Human Adipose-Derived Stem Cells (2023)
193. https://pmc.ncbi.nlm.nih.gov/articles/PMC4211270/ - Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage (2015)
194. https://www.mdpi.com/2076-3921/13/5/602 - Cellular ROS and Antioxidants: Physiological and Pathological Role (2024)
195. https://www.sciencedirect.com/science/article/pii/S1319016422001980 - Resveratrol treatment modulates several antioxidant and anti-inflammatory genes expression and ameliorated oxidative stress mediated fibrosis in the kidneys of high-fat diet-fed rats (2022)